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Kaliumkanalblocker in der Neurologie : 5-MOP ZUR BEHANDLUNG MS-BEDINGTER FUNKTIONSDEFIZITE

Koppenhofer, E. ; Ditzen, G. ; Gerst, F. and Reimers, A. LU (1995) In TW Neurologie Psychiatrie 9(10). p.585-591
Abstract

After common belief the impairment of nerve conduction seen with multiple sclerosis has to do with uncovering of internodal potassium channels. Therefore, suitable potassium channel blockers like 5-methoxypsoralen can alleviate functional deficits due to multiple sclerosis. This has been demonstrated by single tests under well-defined laboratory conditions and by further clinical single trials. With the dosage used, no unwanted side-effects were detected so far. The well-known toxicology of 5-methoxypsoralen emphasizes this finding.

Please use this url to cite or link to this publication:
author
; ; and
alternative title
5-Methoxypsoralen for the treatment of MS-induced functional deficits
publishing date
type
Contribution to journal
publication status
published
in
TW Neurologie Psychiatrie
volume
9
issue
10
pages
585 - 591
publisher
Braun
external identifiers
  • scopus:0028867340
ISSN
0935-3224
language
German
LU publication?
no
id
9ac739db-657e-4eae-80aa-1b76c080a9c6
date added to LUP
2024-08-31 14:59:46
date last changed
2024-09-02 08:10:47
@article{9ac739db-657e-4eae-80aa-1b76c080a9c6,
  abstract     = {{<p>After common belief the impairment of nerve conduction seen with multiple sclerosis has to do with uncovering of internodal potassium channels. Therefore, suitable potassium channel blockers like 5-methoxypsoralen can alleviate functional deficits due to multiple sclerosis. This has been demonstrated by single tests under well-defined laboratory conditions and by further clinical single trials. With the dosage used, no unwanted side-effects were detected so far. The well-known toxicology of 5-methoxypsoralen emphasizes this finding.</p>}},
  author       = {{Koppenhofer, E. and Ditzen, G. and Gerst, F. and Reimers, A.}},
  issn         = {{0935-3224}},
  language     = {{ger}},
  number       = {{10}},
  pages        = {{585--591}},
  publisher    = {{Braun}},
  series       = {{TW Neurologie Psychiatrie}},
  title        = {{Kaliumkanalblocker in der Neurologie : 5-MOP ZUR BEHANDLUNG MS-BEDINGTER FUNKTIONSDEFIZITE}},
  volume       = {{9}},
  year         = {{1995}},
}