[Aldosterone reception by a kidney membrane fraction and cytosol from rats in postnatal ontogeny]
(1989) In Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova 75(2). p.6-251- Abstract
Specific binding of aldosterone by crude membrane fraction, the affinity and maximal concentration of cytosolic receptors of aldosterone were studied in the kidney cortex of the Wistar rats as well as the plasma level and adrenal biosynthesis of aldosterone. The specific binding of aldosterone was found to increase in membrane fraction and to decrease in cytosol during kidney maturation. The affinity of the cytosol receptors to aldosterone did not change in the same period. The level of biosynthesis in adrenals and plasma concentration of aldosterone was higher in adult rather than in young rats. The membrane binding of aldosterone seems to take part in the mechanism of cell sensitivity to aldosterone.
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- author
- Logvinenko, N S ; Svitasheva, N G LU ; Solenov, E I and Ivanova, L N
- publishing date
- 1989
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Adrenal Glands/metabolism, Aging/metabolism, Aldosterone/analysis, Animals, Cell Membrane/metabolism, Cytosol/metabolism, Kidney/metabolism, Male, Rats, Rats, Inbred Strains, Receptors, Glucocorticoid/analysis, Receptors, Mineralocorticoid, Tritium
- in
- Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova
- volume
- 75
- issue
- 2
- pages
- 6 - 251
- publisher
- Izdatel'stvo Nauka
- external identifiers
-
- pmid:2524409
- scopus:0024615014
- ISSN
- 0015-329X
- language
- English
- LU publication?
- no
- id
- 9b16bc37-31c2-4f51-a9c7-7e4bb614eea0
- date added to LUP
- 2020-03-02 08:58:53
- date last changed
- 2024-01-02 06:57:54
@article{9b16bc37-31c2-4f51-a9c7-7e4bb614eea0, abstract = {{<p>Specific binding of aldosterone by crude membrane fraction, the affinity and maximal concentration of cytosolic receptors of aldosterone were studied in the kidney cortex of the Wistar rats as well as the plasma level and adrenal biosynthesis of aldosterone. The specific binding of aldosterone was found to increase in membrane fraction and to decrease in cytosol during kidney maturation. The affinity of the cytosol receptors to aldosterone did not change in the same period. The level of biosynthesis in adrenals and plasma concentration of aldosterone was higher in adult rather than in young rats. The membrane binding of aldosterone seems to take part in the mechanism of cell sensitivity to aldosterone.</p>}}, author = {{Logvinenko, N S and Svitasheva, N G and Solenov, E I and Ivanova, L N}}, issn = {{0015-329X}}, keywords = {{Adrenal Glands/metabolism; Aging/metabolism; Aldosterone/analysis; Animals; Cell Membrane/metabolism; Cytosol/metabolism; Kidney/metabolism; Male; Rats; Rats, Inbred Strains; Receptors, Glucocorticoid/analysis; Receptors, Mineralocorticoid; Tritium}}, language = {{eng}}, number = {{2}}, pages = {{6--251}}, publisher = {{Izdatel'stvo Nauka}}, series = {{Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova}}, title = {{[Aldosterone reception by a kidney membrane fraction and cytosol from rats in postnatal ontogeny]}}, volume = {{75}}, year = {{1989}}, }