Spontaneous hepatic hemorrhage as presentation of metastasized papillary thyroid carcinoma : a case report
Thomasson, Jacob ; Andersson, Bodil LU
; Thompson, Lo Hallin
LU
and Williamsson, Caroline
LU
(2024)
In Journal of Medical Case Reports
18(1).
- Abstract
Background: Spontaneous hepatic hemorrhage is a rare condition, most commonly diagnosed in patients with hepatocellular carcinoma or hepatic adenomas, and is seldom caused by metastatic disease. In this case report, we present a patient with spontaneous hepatic hemorrhage due to hepatic metastasis of papillary thyroid carcinoma, an exceptionally rare occurrence. Case presentation: The patient was a 77-year-old white male with a history of atrial fibrillation treated with apixaban. He presented at a local hospital with abdominal pain and nausea. A CT scan revealed a hepatic lesion in segment 3 with an adjacent hematoma. He was referred to our tertiary center and treated conservatively. Further evaluation revealed an intrathoracic goiter... (More)
Background: Spontaneous hepatic hemorrhage is a rare condition, most commonly diagnosed in patients with hepatocellular carcinoma or hepatic adenomas, and is seldom caused by metastatic disease. In this case report, we present a patient with spontaneous hepatic hemorrhage due to hepatic metastasis of papillary thyroid carcinoma, an exceptionally rare occurrence. Case presentation: The patient was a 77-year-old white male with a history of atrial fibrillation treated with apixaban. He presented at a local hospital with abdominal pain and nausea. A CT scan revealed a hepatic lesion in segment 3 with an adjacent hematoma. He was referred to our tertiary center and treated conservatively. Further evaluation revealed an intrathoracic goiter containing a tumorous process diagnosed as a papillary thyroid carcinoma (PTC), and the patient subsequently underwent thyroidectomy. A biopsy of the hepatic lesion confirmed it as a PTC metastasis. Due to worsening abdominal pain and anorexia, the patient underwent subacute hepatic segmental resection. Postoperatively, he developed iodine-refractory disease with disseminated metastasis and passed away 22 months after the initial admission. Conclusions: To our knowledge, this is the first recorded case of metastasized papillary thyroid carcinoma presenting with spontaneous hepatic hemorrhage—adding to the list of rare causes for this condition.
(Less)
- author
- Thomasson, Jacob
; Andersson, Bodil
LU
; Thompson, Lo Hallin
LU
and Williamsson, Caroline
LU
- organization
- publishing date
- 2024-12
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Case report, Hepatic metastasis, Papillary thyroid carcinoma, Spontaneous hepatic hemorrhage
- in
- Journal of Medical Case Reports
- volume
- 18
- issue
- 1
- article number
- 462
- publisher
- BioMed Central (BMC)
- external identifiers
-
- pmid:39313807
- scopus:85204904693
- ISSN
- 1752-1947
- DOI
- 10.1186/s13256-024-04797-5
- language
- English
- LU publication?
- yes
- id
- 9b39ae23-3a16-4cf4-a1f8-12a14a5311df
- date added to LUP
- 2025-01-09 15:09:23
- date last changed
- 2025-07-11 06:26:23
@article{9b39ae23-3a16-4cf4-a1f8-12a14a5311df,
abstract = {{<p>Background: Spontaneous hepatic hemorrhage is a rare condition, most commonly diagnosed in patients with hepatocellular carcinoma or hepatic adenomas, and is seldom caused by metastatic disease. In this case report, we present a patient with spontaneous hepatic hemorrhage due to hepatic metastasis of papillary thyroid carcinoma, an exceptionally rare occurrence. Case presentation: The patient was a 77-year-old white male with a history of atrial fibrillation treated with apixaban. He presented at a local hospital with abdominal pain and nausea. A CT scan revealed a hepatic lesion in segment 3 with an adjacent hematoma. He was referred to our tertiary center and treated conservatively. Further evaluation revealed an intrathoracic goiter containing a tumorous process diagnosed as a papillary thyroid carcinoma (PTC), and the patient subsequently underwent thyroidectomy. A biopsy of the hepatic lesion confirmed it as a PTC metastasis. Due to worsening abdominal pain and anorexia, the patient underwent subacute hepatic segmental resection. Postoperatively, he developed iodine-refractory disease with disseminated metastasis and passed away 22 months after the initial admission. Conclusions: To our knowledge, this is the first recorded case of metastasized papillary thyroid carcinoma presenting with spontaneous hepatic hemorrhage—adding to the list of rare causes for this condition.</p>}},
author = {{Thomasson, Jacob and Andersson, Bodil and Thompson, Lo Hallin and Williamsson, Caroline}},
issn = {{1752-1947}},
keywords = {{Case report; Hepatic metastasis; Papillary thyroid carcinoma; Spontaneous hepatic hemorrhage}},
language = {{eng}},
number = {{1}},
publisher = {{BioMed Central (BMC)}},
series = {{Journal of Medical Case Reports}},
title = {{Spontaneous hepatic hemorrhage as presentation of metastasized papillary thyroid carcinoma : a case report}},
url = {{http://dx.doi.org/10.1186/s13256-024-04797-5}},
doi = {{10.1186/s13256-024-04797-5}},
volume = {{18}},
year = {{2024}},
}