Novel method for the synthesis of molecularly imprinted polymer bead libraries
(2004) In Macromolecular Rapid Communications 25(1). p.315-320- Abstract
- A novel method for the synthesis of spherical molecularly imprinted polymer (MIP) beads by suspension polymerization in mineral oil is described. The usefulness of the method was demonstrated by the synthesis of a propranolol imprinted MIP library. The composition of the library was generated by statistical experimental design. Multivariate data analysis correlated the screening data, obtained by a radioligand binding assay, to the composition of the MIPs.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/288984
- author
- Kempe, Henrik LU and Kempe, Maria LU
- organization
- publishing date
- 2004
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- bead, spherical, molecular imprinting, chemometrics, combinatorial library, suspension polymerization
- in
- Macromolecular Rapid Communications
- volume
- 25
- issue
- 1
- pages
- 315 - 320
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- wos:000188385300037
- scopus:0442325291
- ISSN
- 1022-1336
- DOI
- 10.1002/marc.200300189
- language
- English
- LU publication?
- yes
- id
- 9b969e2b-ae2f-47b2-96c6-1838da57adb0 (old id 288984)
- date added to LUP
- 2016-04-01 12:16:52
- date last changed
- 2022-03-21 02:01:09
@article{9b969e2b-ae2f-47b2-96c6-1838da57adb0, abstract = {{A novel method for the synthesis of spherical molecularly imprinted polymer (MIP) beads by suspension polymerization in mineral oil is described. The usefulness of the method was demonstrated by the synthesis of a propranolol imprinted MIP library. The composition of the library was generated by statistical experimental design. Multivariate data analysis correlated the screening data, obtained by a radioligand binding assay, to the composition of the MIPs.}}, author = {{Kempe, Henrik and Kempe, Maria}}, issn = {{1022-1336}}, keywords = {{bead; spherical; molecular imprinting; chemometrics; combinatorial library; suspension polymerization}}, language = {{eng}}, number = {{1}}, pages = {{315--320}}, publisher = {{John Wiley & Sons Inc.}}, series = {{Macromolecular Rapid Communications}}, title = {{Novel method for the synthesis of molecularly imprinted polymer bead libraries}}, url = {{http://dx.doi.org/10.1002/marc.200300189}}, doi = {{10.1002/marc.200300189}}, volume = {{25}}, year = {{2004}}, }