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Chapter 40 - Lymphocyte Trafficking to Mucosal Tissues

Mikhak, Zamaneh; Agace, William W. LU and Luster, Andrew D. (2015) 1-2. p.805-830
Abstract

Lymphocytes are the key cells of the adaptive immune system that provide antigen-specific responses tailored to the context of antigen exposure. Through cytokine release and antibody production, lymphocytes orchestrate and amplify the recruitment and function of other immune cells and contribute to host defense against invading pathogens and the pathogenesis of many inflammatory diseases. Lymphocyte function is critically dependent on their ability to traffic into the correct anatomic locations at the appropriate times. This process is highly regulated and requires that lymphocytes interact with various homing molecules and respond to tightly regulated navigational cues.

Please use this url to cite or link to this publication:
author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Cell migration, Cell trafficking, Chemoattractants, Chemokines, Chemotaxis, Gut, Homing, Imprinting, Integrins, Lung, Mucosal immunology, T cells
host publication
Mucosal Immunology
volume
1-2
pages
805 - 830
publisher
Elsevier Inc.
external identifiers
  • scopus:84939477447
ISBN
9780124159754
9780124158474
DOI
10.1016/B978-0-12-415847-4.00040-9
language
English
LU publication?
yes
id
9c63b627-3681-4e67-97d4-376428abdd11
date added to LUP
2019-05-30 13:48:53
date last changed
2019-06-03 12:54:56
@inbook{9c63b627-3681-4e67-97d4-376428abdd11,
  abstract     = {<p>Lymphocytes are the key cells of the adaptive immune system that provide antigen-specific responses tailored to the context of antigen exposure. Through cytokine release and antibody production, lymphocytes orchestrate and amplify the recruitment and function of other immune cells and contribute to host defense against invading pathogens and the pathogenesis of many inflammatory diseases. Lymphocyte function is critically dependent on their ability to traffic into the correct anatomic locations at the appropriate times. This process is highly regulated and requires that lymphocytes interact with various homing molecules and respond to tightly regulated navigational cues.</p>},
  author       = {Mikhak, Zamaneh and Agace, William W. and Luster, Andrew D.},
  isbn         = {9780124159754},
  keyword      = {Cell migration,Cell trafficking,Chemoattractants,Chemokines,Chemotaxis,Gut,Homing,Imprinting,Integrins,Lung,Mucosal immunology,T cells},
  language     = {eng},
  month        = {04},
  pages        = {805--830},
  publisher    = {Elsevier Inc.},
  title        = {Chapter 40 - Lymphocyte Trafficking to Mucosal Tissues},
  url          = {http://dx.doi.org/10.1016/B978-0-12-415847-4.00040-9},
  volume       = {1-2},
  year         = {2015},
}