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Air Pollution and Cognitive Impairment across the Life Course in Humans : A Systematic Review with Specific Focus on Income Level of Study Area

Chandra, Mina ; Rai, Chandra Bhushan ; Kumari, Neelam ; Sandhu, Vipindeep Kaur ; Chandra, Kalpana ; Krishna, Murali ; Kota, Sri Harsha ; Anand, Kuljeet Singh and Oudin, Anna LU orcid (2022) In International Journal of Environmental Research and Public Health 19(3).
Abstract

Cognitive function is a crucial determinant of human capital. The Lancet Commission (2020) has recognized air pollution as a risk factor for dementia. However, the scientific evidence on the impact of air pollution on cognitive outcomes across the life course and across different income settings, with varying levels of air pollution, needs further exploration. A systematic review was conducted, using Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) Guidelines to assess the association between air pollution and cognitive outcomes across the life course with a plan to analyze findings as per the income status of the study population. The PubMed search included keywords related to cognition and to pollution (in... (More)

Cognitive function is a crucial determinant of human capital. The Lancet Commission (2020) has recognized air pollution as a risk factor for dementia. However, the scientific evidence on the impact of air pollution on cognitive outcomes across the life course and across different income settings, with varying levels of air pollution, needs further exploration. A systematic review was conducted, using Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) Guidelines to assess the association between air pollution and cognitive outcomes across the life course with a plan to analyze findings as per the income status of the study population. The PubMed search included keywords related to cognition and to pollution (in their titles) to identify studies on human participants published in English until 10 July 2020. The search yielded 84 relevant studies that described associations between exposure to air pollutants and an increased risk of lower cognitive function among children and adolescents, cognitive impairment and decline among adults, and dementia among older adults with supportive evidence of neuroimaging and inflammatory biomarkers. No study from low-and middle-income countries (LMICs)was identified despite high levels of air pollutants and high rates of dementia. To conclude, air pollution may impair cognitive function across the life-course, but a paucity of studies from reLMICs is a major lacuna in research.

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author
; ; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Air pollution, Cognition, Cognitive impairment, Dementia, Global pollution, Health effects/risks, PAH, Particulate matter (PM )
in
International Journal of Environmental Research and Public Health
volume
19
issue
3
article number
1405
publisher
MDPI AG
external identifiers
  • scopus:85123373888
  • pmid:35162428
ISSN
1661-7827
DOI
10.3390/ijerph19031405
project
How is our health affected by particles from wood burning?
language
English
LU publication?
yes
id
9c9c541a-6c4a-4399-8b70-af710dd92b10
date added to LUP
2022-03-18 14:59:12
date last changed
2025-04-18 17:33:55
@article{9c9c541a-6c4a-4399-8b70-af710dd92b10,
  abstract     = {{<p>Cognitive function is a crucial determinant of human capital. The Lancet Commission (2020) has recognized air pollution as a risk factor for dementia. However, the scientific evidence on the impact of air pollution on cognitive outcomes across the life course and across different income settings, with varying levels of air pollution, needs further exploration. A systematic review was conducted, using Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) Guidelines to assess the association between air pollution and cognitive outcomes across the life course with a plan to analyze findings as per the income status of the study population. The PubMed search included keywords related to cognition and to pollution (in their titles) to identify studies on human participants published in English until 10 July 2020. The search yielded 84 relevant studies that described associations between exposure to air pollutants and an increased risk of lower cognitive function among children and adolescents, cognitive impairment and decline among adults, and dementia among older adults with supportive evidence of neuroimaging and inflammatory biomarkers. No study from low-and middle-income countries (LMICs)was identified despite high levels of air pollutants and high rates of dementia. To conclude, air pollution may impair cognitive function across the life-course, but a paucity of studies from reLMICs is a major lacuna in research.</p>}},
  author       = {{Chandra, Mina and Rai, Chandra Bhushan and Kumari, Neelam and Sandhu, Vipindeep Kaur and Chandra, Kalpana and Krishna, Murali and Kota, Sri Harsha and Anand, Kuljeet Singh and Oudin, Anna}},
  issn         = {{1661-7827}},
  keywords     = {{Air pollution; Cognition; Cognitive impairment; Dementia; Global pollution; Health effects/risks; PAH; Particulate matter (PM )}},
  language     = {{eng}},
  number       = {{3}},
  publisher    = {{MDPI AG}},
  series       = {{International Journal of Environmental Research and Public Health}},
  title        = {{Air Pollution and Cognitive Impairment across the Life Course in Humans : A Systematic Review with Specific Focus on Income Level of Study Area}},
  url          = {{http://dx.doi.org/10.3390/ijerph19031405}},
  doi          = {{10.3390/ijerph19031405}},
  volume       = {{19}},
  year         = {{2022}},
}