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A Retrospective Study of Aimed Patch Testing with Aqueous Nickel Sulfate Hexahydrate at 30% and 15% in Patients with Dermatitis

Bruze, Magnus LU ; Hindsén, Monica LU and Mowitz, Martin LU (2018) In Dermatitis 29(4). p.193-195
Abstract

Background Sometimes, patients with a history of metal intolerance react negatively or doubtfully to nickel at patch testing. Objective The aim of the study was to investigate whether aqueous nickel sulfate hexahydrate at 15% and 30% traces more contact allergy than the nickel preparation in the baseline series at 5%. Methods In the period 1995-2015, more than 800 of 16,059 patients with a negative or doubtful patch test reaction to the petrolatum preparation of nickel at 5% on the day 3 reading were additionally tested with aqueous nickel at 15% and/or 30%. Conclusions In this retrospective study with aimed patch testing with aqueous nickel solutions, significantly more (P < 0.001) contact allergy was obtained as compared with the... (More)

Background Sometimes, patients with a history of metal intolerance react negatively or doubtfully to nickel at patch testing. Objective The aim of the study was to investigate whether aqueous nickel sulfate hexahydrate at 15% and 30% traces more contact allergy than the nickel preparation in the baseline series at 5%. Methods In the period 1995-2015, more than 800 of 16,059 patients with a negative or doubtful patch test reaction to the petrolatum preparation of nickel at 5% on the day 3 reading were additionally tested with aqueous nickel at 15% and/or 30%. Conclusions In this retrospective study with aimed patch testing with aqueous nickel solutions, significantly more (P < 0.001) contact allergy was obtained as compared with the 5% preparation in petrolatum. The 30% solution was significantly better (P < 0.001) than the 15% solution. To demonstrate that patch testing with nickel at 15% or 30% is better than the present testing with 5% requires simultaneous testing with the 3 nickel preparations.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Dermatitis
volume
29
issue
4
pages
3 pages
publisher
BC Decker
external identifiers
  • scopus:85050645922
  • pmid:30024450
ISSN
1710-3568
DOI
10.1097/DER.0000000000000388
language
English
LU publication?
yes
id
9d2f3ffd-a6a0-4e5b-a92e-8e2d4ecd337e
date added to LUP
2018-09-03 15:26:40
date last changed
2020-01-13 00:54:35
@article{9d2f3ffd-a6a0-4e5b-a92e-8e2d4ecd337e,
  abstract     = {<p>Background Sometimes, patients with a history of metal intolerance react negatively or doubtfully to nickel at patch testing. Objective The aim of the study was to investigate whether aqueous nickel sulfate hexahydrate at 15% and 30% traces more contact allergy than the nickel preparation in the baseline series at 5%. Methods In the period 1995-2015, more than 800 of 16,059 patients with a negative or doubtful patch test reaction to the petrolatum preparation of nickel at 5% on the day 3 reading were additionally tested with aqueous nickel at 15% and/or 30%. Conclusions In this retrospective study with aimed patch testing with aqueous nickel solutions, significantly more (P &lt; 0.001) contact allergy was obtained as compared with the 5% preparation in petrolatum. The 30% solution was significantly better (P &lt; 0.001) than the 15% solution. To demonstrate that patch testing with nickel at 15% or 30% is better than the present testing with 5% requires simultaneous testing with the 3 nickel preparations.</p>},
  author       = {Bruze, Magnus and Hindsén, Monica and Mowitz, Martin},
  issn         = {1710-3568},
  language     = {eng},
  month        = {07},
  number       = {4},
  pages        = {193--195},
  publisher    = {BC Decker},
  series       = {Dermatitis},
  title        = {A Retrospective Study of Aimed Patch Testing with Aqueous Nickel Sulfate Hexahydrate at 30% and 15% in Patients with Dermatitis},
  url          = {http://dx.doi.org/10.1097/DER.0000000000000388},
  doi          = {10.1097/DER.0000000000000388},
  volume       = {29},
  year         = {2018},
}