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The perceived threat of the risk for graft rejection and health related quality of life among organ transplant recipient's.

Nilsson, Madeleine ; Forsberg, Anna LU ; Bäckman, Lars ; Lennerling, Annette and Persson, Lars-Olof (2011) In Journal of Clinical Nursing 20(1-2). p.274-282
Abstract
Aims. This study was primarily aimed for developing and testing a valid and reliable instrument that measures perceived threat of the risk for graft rejection after organ transplantation. A second aim was to report descriptive data regarding graft rejection and Health‐Related Quality of Life.
Background. The most serious risk connected with transplantations besides infection is graft rejection.
Design. Non experimental, descriptive involving instrument development and psychometric assessment.
Method. Questionnaires about perceived threat of the risk for graft rejection and Health‐Related Quality of Life were mailed to 229 OTRs between 19–65 years old. The items were formed from a previous interview study. Patients were... (More)
Aims. This study was primarily aimed for developing and testing a valid and reliable instrument that measures perceived threat of the risk for graft rejection after organ transplantation. A second aim was to report descriptive data regarding graft rejection and Health‐Related Quality of Life.
Background. The most serious risk connected with transplantations besides infection is graft rejection.
Design. Non experimental, descriptive involving instrument development and psychometric assessment.
Method. Questionnaires about perceived threat of the risk for graft rejection and Health‐Related Quality of Life were mailed to 229 OTRs between 19–65 years old. The items were formed from a previous interview study. Patients were transplanted with a kidney, a liver or a heart and/or a lung. All patients with follow‐up time of one year ± three months and three years ± three months were included.
Results. With an 81% response rate, the study comprised of 185 OTRs, who had received either a kidney (n = 117), a liver (n = 39) or heart or lung (n = 29). Three homogenous factors of perceived threat for graft rejection were revealed, labelled ‘intrusive anxiety’, ‘graft‐related threat’ and ‘lack of control’. Tests of internal consistency showed good item‐scale convergent and discriminatory validity. A majority of the OTRs scored low levels for ‘intrusive anxiety’. The kidney transplant recipients experienced more ‘graft‐related threat’ by acute graft rejection than those transplanted with a liver, heart or lung.
Conclusion. In conclusion, this study suggests that it is possible to measure the perceived threat of the risk for graft rejection in three homogenous factors.
Relevance to clinical practice. The instrument perceived threat of the risk for graft rejection, might be usable to measure the impact of fear of graft rejection, to predict needs of pedagogical intervention strategies to reduce fear and to improve Health‐Related Quality of Life related to graft rejection.
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author
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publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Clinical Nursing
volume
20
issue
1-2
pages
274 - 282
publisher
Wiley-Blackwell
external identifiers
  • scopus:78650234356
ISSN
1365-2702
DOI
10.1111/j.1365-2702.2010.03388.x
language
English
LU publication?
no
id
9dcb6b66-8ee2-4654-9382-c09bb716332b
date added to LUP
2019-06-01 20:49:22
date last changed
2020-12-08 04:36:14
@article{9dcb6b66-8ee2-4654-9382-c09bb716332b,
  abstract     = {Aims. This study was primarily aimed for developing and testing a valid and reliable instrument that measures perceived threat of the risk for graft rejection after organ transplantation. A second aim was to report descriptive data regarding graft rejection and Health‐Related Quality of Life.<br/>Background. The most serious risk connected with transplantations besides infection is graft rejection.<br/>Design. Non experimental, descriptive involving instrument development and psychometric assessment.<br/>Method. Questionnaires about perceived threat of the risk for graft rejection and Health‐Related Quality of Life were mailed to 229 OTRs between 19–65 years old. The items were formed from a previous interview study. Patients were transplanted with a kidney, a liver or a heart and/or a lung. All patients with follow‐up time of one year ± three months and three years ± three months were included.<br/>Results. With an 81% response rate, the study comprised of 185 OTRs, who had received either a kidney (n = 117), a liver (n = 39) or heart or lung (n = 29). Three homogenous factors of perceived threat for graft rejection were revealed, labelled ‘intrusive anxiety’, ‘graft‐related threat’ and ‘lack of control’. Tests of internal consistency showed good item‐scale convergent and discriminatory validity. A majority of the OTRs scored low levels for ‘intrusive anxiety’. The kidney transplant recipients experienced more ‘graft‐related threat’ by acute graft rejection than those transplanted with a liver, heart or lung.<br/>Conclusion. In conclusion, this study suggests that it is possible to measure the perceived threat of the risk for graft rejection in three homogenous factors.<br/>Relevance to clinical practice. The instrument perceived threat of the risk for graft rejection, might be usable to measure the impact of fear of graft rejection, to predict needs of pedagogical intervention strategies to reduce fear and to improve Health‐Related Quality of Life related to graft rejection.<br/>},
  author       = {Nilsson, Madeleine and Forsberg, Anna and Bäckman, Lars and Lennerling, Annette and Persson, Lars-Olof},
  issn         = {1365-2702},
  language     = {eng},
  number       = {1-2},
  pages        = {274--282},
  publisher    = {Wiley-Blackwell},
  series       = {Journal of Clinical Nursing},
  title        = {The perceived threat of the risk for graft rejection and health related quality of life among organ transplant recipient's.},
  url          = {http://dx.doi.org/10.1111/j.1365-2702.2010.03388.x},
  doi          = {10.1111/j.1365-2702.2010.03388.x},
  volume       = {20},
  year         = {2011},
}