Penicillin-resistant pneumococci in Sweden 1997-2003: Increased multiresistance despite stable prevalence and decreased antibiotic use
(2006) In Microbial Drug Resistance 12(1). p.16-22- Abstract
- Antimicrobial resistance patterns and capsular groups of penicillin-resistant Streptococcus pneumoniae (PRP; MIC penicillin G >= 0.5 mg/ml) in Sweden between 1997 and 2003 were described, and trends in resistance and antibiotic sales during the same period were compared. The most common serogroups were in descending order 9, 19, 14, 23, and 6. Despite a low and stable annual PRP rate (proportion of PRP out of all pneumococci) of around 2% during the study period, the proportion of PRP resistant to other antibiotics increased. Of all tested PRP isolates, 82% were also resistant to trimethoprim/sulfamethoxazole, 32% had additional resistance to tetracycline, and 26% to erythromycin. Antibiotic sales figures for all studied antibiotic... (More)
- Antimicrobial resistance patterns and capsular groups of penicillin-resistant Streptococcus pneumoniae (PRP; MIC penicillin G >= 0.5 mg/ml) in Sweden between 1997 and 2003 were described, and trends in resistance and antibiotic sales during the same period were compared. The most common serogroups were in descending order 9, 19, 14, 23, and 6. Despite a low and stable annual PRP rate (proportion of PRP out of all pneumococci) of around 2% during the study period, the proportion of PRP resistant to other antibiotics increased. Of all tested PRP isolates, 82% were also resistant to trimethoprim/sulfamethoxazole, 32% had additional resistance to tetracycline, and 26% to erythromycin. Antibiotic sales figures for all studied antibiotic subgroups decreased during the same period. Little correlation was found between antibiotic sales and PRP resistance rates, indicating that there are still other poorly defined factors contributing to the reported resistance levels in the population. However, although PRP strains in Sweden are becoming more commonly resistant to antibiotics other than beta-lactams, the low and further reduced antibiotic sales still might have delayed the development and rapid spread of PRP in the population. (Less)
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https://lup.lub.lu.se/record/413971
- author
- Hogberg, L ; Ekdahl, K ; Sjostrom, K ; Olsson-Liljequist, B ; Walder, Mats LU ; Melander, E ; Ringberg, H and Normark, BH
- organization
- publishing date
- 2006
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Microbial Drug Resistance
- volume
- 12
- issue
- 1
- pages
- 16 - 22
- publisher
- Mary Ann Liebert, Inc.
- external identifiers
-
- wos:000236686300004
- scopus:33646028165
- ISSN
- 1076-6294
- DOI
- 10.1089/mdr.2006.12.16
- language
- English
- LU publication?
- yes
- id
- 9e5fcd85-3efa-4e1d-ac18-6bc796f86032 (old id 413971)
- date added to LUP
- 2016-04-01 16:12:37
- date last changed
- 2022-01-28 18:06:45
@article{9e5fcd85-3efa-4e1d-ac18-6bc796f86032,
abstract = {{Antimicrobial resistance patterns and capsular groups of penicillin-resistant Streptococcus pneumoniae (PRP; MIC penicillin G >= 0.5 mg/ml) in Sweden between 1997 and 2003 were described, and trends in resistance and antibiotic sales during the same period were compared. The most common serogroups were in descending order 9, 19, 14, 23, and 6. Despite a low and stable annual PRP rate (proportion of PRP out of all pneumococci) of around 2% during the study period, the proportion of PRP resistant to other antibiotics increased. Of all tested PRP isolates, 82% were also resistant to trimethoprim/sulfamethoxazole, 32% had additional resistance to tetracycline, and 26% to erythromycin. Antibiotic sales figures for all studied antibiotic subgroups decreased during the same period. Little correlation was found between antibiotic sales and PRP resistance rates, indicating that there are still other poorly defined factors contributing to the reported resistance levels in the population. However, although PRP strains in Sweden are becoming more commonly resistant to antibiotics other than beta-lactams, the low and further reduced antibiotic sales still might have delayed the development and rapid spread of PRP in the population.}},
author = {{Hogberg, L and Ekdahl, K and Sjostrom, K and Olsson-Liljequist, B and Walder, Mats and Melander, E and Ringberg, H and Normark, BH}},
issn = {{1076-6294}},
language = {{eng}},
number = {{1}},
pages = {{16--22}},
publisher = {{Mary Ann Liebert, Inc.}},
series = {{Microbial Drug Resistance}},
title = {{Penicillin-resistant pneumococci in Sweden 1997-2003: Increased multiresistance despite stable prevalence and decreased antibiotic use}},
url = {{http://dx.doi.org/10.1089/mdr.2006.12.16}},
doi = {{10.1089/mdr.2006.12.16}},
volume = {{12}},
year = {{2006}},
}