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Measurement of pulmonary density by means of X-ray computerized tomography. Relation to pulmonary mechanics in normal subjects

Wollmer, P LU ; Albrechtsson, U LU ; Brauer, K LU ; Eriksson, L LU ; Jonson, B LU and Tylèn, Ulf (1986) In Chest 90(3). p.91-387
Abstract

We examined the relationship between pulmonary density, measured with computerized tomography, and pulmonary mechanics (static pulmonary volume; pulmonary resistance) in 39 normal subjects (20 nonsmokers and 19 smokers). Pulmonary density decreased with increasing static elastic recoil pressure, and smokers consistently showed higher pulmonary density than nonsmokers. Pulmonary density, measured at full inspiration, correlated inversely with total lung capacity. Pulmonary density showed a ventrodorsal gradient, which was greater at low elastic recoil pressure than at high recoil pressure. The study shows that pulmonary density is related to the mechanical properties of the lung in normal subjects. Increased pulmonary density appears to... (More)

We examined the relationship between pulmonary density, measured with computerized tomography, and pulmonary mechanics (static pulmonary volume; pulmonary resistance) in 39 normal subjects (20 nonsmokers and 19 smokers). Pulmonary density decreased with increasing static elastic recoil pressure, and smokers consistently showed higher pulmonary density than nonsmokers. Pulmonary density, measured at full inspiration, correlated inversely with total lung capacity. Pulmonary density showed a ventrodorsal gradient, which was greater at low elastic recoil pressure than at high recoil pressure. The study shows that pulmonary density is related to the mechanical properties of the lung in normal subjects. Increased pulmonary density appears to be a sensitive indicator of pulmonary damage induced by smoking. Further studies of the relationship between pulmonary density and pulmonary mechanics in disease seem warranted.

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organization
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type
Contribution to journal
publication status
published
subject
keywords
Aged, Biomechanical Phenomena, Humans, Lung, Lung Compliance, Lung Volume Measurements, Male, Middle Aged, Smoking, Tomography, X-Ray Computed, Journal Article
in
Chest
volume
90
issue
3
pages
5 pages
publisher
American College of Chest Physicians
external identifiers
  • scopus:0022448749
ISSN
0012-3692
DOI
10.1378/chest.90.3.387
language
English
LU publication?
yes
id
9eb6cde4-89d1-4c3d-bd92-2fded4d578c1
date added to LUP
2017-06-13 14:08:40
date last changed
2017-07-25 14:22:45
@article{9eb6cde4-89d1-4c3d-bd92-2fded4d578c1,
  abstract     = {<p>We examined the relationship between pulmonary density, measured with computerized tomography, and pulmonary mechanics (static pulmonary volume; pulmonary resistance) in 39 normal subjects (20 nonsmokers and 19 smokers). Pulmonary density decreased with increasing static elastic recoil pressure, and smokers consistently showed higher pulmonary density than nonsmokers. Pulmonary density, measured at full inspiration, correlated inversely with total lung capacity. Pulmonary density showed a ventrodorsal gradient, which was greater at low elastic recoil pressure than at high recoil pressure. The study shows that pulmonary density is related to the mechanical properties of the lung in normal subjects. Increased pulmonary density appears to be a sensitive indicator of pulmonary damage induced by smoking. Further studies of the relationship between pulmonary density and pulmonary mechanics in disease seem warranted.</p>},
  author       = {Wollmer, P and Albrechtsson, U and Brauer, K and Eriksson, L and Jonson, B and Tylèn, Ulf},
  issn         = {0012-3692},
  keyword      = {Aged,Biomechanical Phenomena,Humans,Lung,Lung Compliance,Lung Volume Measurements,Male,Middle Aged,Smoking,Tomography, X-Ray Computed,Journal Article},
  language     = {eng},
  number       = {3},
  pages        = {91--387},
  publisher    = {American College of Chest Physicians},
  series       = {Chest},
  title        = {Measurement of pulmonary density by means of X-ray computerized tomography. Relation to pulmonary mechanics in normal subjects},
  url          = {http://dx.doi.org/10.1378/chest.90.3.387},
  volume       = {90},
  year         = {1986},
}