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Slow light for deep tissue imaging with ultrasound modulation

Zhang, Huiliang ; Sabooni, Mahmood LU ; Rippe, Lars LU ; Kim, Chulhong ; Kröll, Stefan LU ; Wang, Lihong V. and Hemmer, Philip R. (2012) In Applied Physics Letters 100(13).
Abstract
Slow light has been extensively studied for applications ranging from optical delay lines to single photon quantum storage. Here, we show that the time delay of slow-light significantly improves the performance of the narrowband spectral filters needed to optically detect ultrasound from deep inside highly scattering tissue. We demonstrate this capability with a 9 cm thick tissue phantom, having 10 cm(-1) reduced scattering coefficient, and achieve an unprecedented background-free signal. Based on the data, we project real time imaging at video rates in even thicker phantoms and possibly deep enough into real tissue for clinical applications like early cancer detection. VC 2012 American Institute of Physics.... (More)
Slow light has been extensively studied for applications ranging from optical delay lines to single photon quantum storage. Here, we show that the time delay of slow-light significantly improves the performance of the narrowband spectral filters needed to optically detect ultrasound from deep inside highly scattering tissue. We demonstrate this capability with a 9 cm thick tissue phantom, having 10 cm(-1) reduced scattering coefficient, and achieve an unprecedented background-free signal. Based on the data, we project real time imaging at video rates in even thicker phantoms and possibly deep enough into real tissue for clinical applications like early cancer detection. VC 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.3696307] (Less)
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Applied Physics Letters
volume
100
issue
13
publisher
American Institute of Physics (AIP)
external identifiers
  • wos:000302230800002
  • scopus:84859540250
  • pmid:22509069
ISSN
0003-6951
DOI
10.1063/1.3696307
language
English
LU publication?
yes
id
9f636694-113c-4f49-b06b-8560aaa2534d (old id 2591088)
date added to LUP
2016-04-01 10:52:44
date last changed
2023-11-10 07:42:03
@article{9f636694-113c-4f49-b06b-8560aaa2534d,
  abstract     = {{Slow light has been extensively studied for applications ranging from optical delay lines to single photon quantum storage. Here, we show that the time delay of slow-light significantly improves the performance of the narrowband spectral filters needed to optically detect ultrasound from deep inside highly scattering tissue. We demonstrate this capability with a 9 cm thick tissue phantom, having 10 cm(-1) reduced scattering coefficient, and achieve an unprecedented background-free signal. Based on the data, we project real time imaging at video rates in even thicker phantoms and possibly deep enough into real tissue for clinical applications like early cancer detection. VC 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.3696307]}},
  author       = {{Zhang, Huiliang and Sabooni, Mahmood and Rippe, Lars and Kim, Chulhong and Kröll, Stefan and Wang, Lihong V. and Hemmer, Philip R.}},
  issn         = {{0003-6951}},
  language     = {{eng}},
  number       = {{13}},
  publisher    = {{American Institute of Physics (AIP)}},
  series       = {{Applied Physics Letters}},
  title        = {{Slow light for deep tissue imaging with ultrasound modulation}},
  url          = {{https://lup.lub.lu.se/search/files/2205200/2969026.pdf}},
  doi          = {{10.1063/1.3696307}},
  volume       = {{100}},
  year         = {{2012}},
}