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Association between sleep duration and executive function differs between diabetic and non-diabetic middle-aged and older adults

Titova, Olga E. ; Lindberg, Eva ; Tan, Xiao ; Elmståhl, Sölve LU ; Lind, Lars ; Schiöth, Helgi B. and Benedict, Christian (2020) In Psychoneuroendocrinology 111.
Abstract

Executive function is defined as a set of cognitive skills that are necessary to plan, monitor, and execute a sequence of goal-directed complex actions. Executive function is influenced by a variety of factors, including habitual sleep duration and diabetes. In the present study, we investigated in 18,769 Swedish adults (mean age: 61 y) the association between executive function, diabetes, and self-reported sleep duration. We observed a significant interaction between diabetes and sleep duration for the Trail Making Test (TMT) ratio (P < 0.01). This ratio is a measure of executive function where higher values indicate worse performance. Among diabetic participants (n = 1,523), long (defined as ≥9 h per day) vs. normal sleep duration... (More)

Executive function is defined as a set of cognitive skills that are necessary to plan, monitor, and execute a sequence of goal-directed complex actions. Executive function is influenced by a variety of factors, including habitual sleep duration and diabetes. In the present study, we investigated in 18,769 Swedish adults (mean age: 61 y) the association between executive function, diabetes, and self-reported sleep duration. We observed a significant interaction between diabetes and sleep duration for the Trail Making Test (TMT) ratio (P < 0.01). This ratio is a measure of executive function where higher values indicate worse performance. Among diabetic participants (n = 1,523), long (defined as ≥9 h per day) vs. normal sleep duration (defined as 7–8 hours per day) was associated with a higher TMT ratio (P < 0.05). Similar significant results were observed in diabetic individuals without pharmacological treatment for diabetes (n = 1,062). Among non-diabetic participants (n = 17,246), no association between long sleep duration and the TMT ratio was observed (P > 0.05). Instead, short (defined as <7 h per day) vs. normal sleep duration was linked to a higher TMT ratio (P < 0.05). These findings suggest that the association between sleep duration and executive function differs between diabetic and non-diabetic middle-aged and older adults. Based on the cross-sectional design of the study, no firm conclusions can be drawn on the causality of the relations.

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author
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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Cohort study, Diabetes, Executive function, Sleep duration
in
Psychoneuroendocrinology
volume
111
article number
104472
publisher
Elsevier
external identifiers
  • scopus:85073016235
  • pmid:31610410
ISSN
0306-4530
DOI
10.1016/j.psyneuen.2019.104472
language
English
LU publication?
yes
id
9f6581f6-9e39-4945-9655-1e61a6d5c401
date added to LUP
2021-01-15 10:33:54
date last changed
2024-05-16 03:03:08
@article{9f6581f6-9e39-4945-9655-1e61a6d5c401,
  abstract     = {{<p>Executive function is defined as a set of cognitive skills that are necessary to plan, monitor, and execute a sequence of goal-directed complex actions. Executive function is influenced by a variety of factors, including habitual sleep duration and diabetes. In the present study, we investigated in 18,769 Swedish adults (mean age: 61 y) the association between executive function, diabetes, and self-reported sleep duration. We observed a significant interaction between diabetes and sleep duration for the Trail Making Test (TMT) ratio (P &lt; 0.01). This ratio is a measure of executive function where higher values indicate worse performance. Among diabetic participants (n = 1,523), long (defined as ≥9 h per day) vs. normal sleep duration (defined as 7–8 hours per day) was associated with a higher TMT ratio (P &lt; 0.05). Similar significant results were observed in diabetic individuals without pharmacological treatment for diabetes (n = 1,062). Among non-diabetic participants (n = 17,246), no association between long sleep duration and the TMT ratio was observed (P &gt; 0.05). Instead, short (defined as &lt;7 h per day) vs. normal sleep duration was linked to a higher TMT ratio (P &lt; 0.05). These findings suggest that the association between sleep duration and executive function differs between diabetic and non-diabetic middle-aged and older adults. Based on the cross-sectional design of the study, no firm conclusions can be drawn on the causality of the relations.</p>}},
  author       = {{Titova, Olga E. and Lindberg, Eva and Tan, Xiao and Elmståhl, Sölve and Lind, Lars and Schiöth, Helgi B. and Benedict, Christian}},
  issn         = {{0306-4530}},
  keywords     = {{Cohort study; Diabetes; Executive function; Sleep duration}},
  language     = {{eng}},
  publisher    = {{Elsevier}},
  series       = {{Psychoneuroendocrinology}},
  title        = {{Association between sleep duration and executive function differs between diabetic and non-diabetic middle-aged and older adults}},
  url          = {{http://dx.doi.org/10.1016/j.psyneuen.2019.104472}},
  doi          = {{10.1016/j.psyneuen.2019.104472}},
  volume       = {{111}},
  year         = {{2020}},
}