Association between sleep duration and executive function differs between diabetic and non-diabetic middle-aged and older adults
(2020) In Psychoneuroendocrinology 111.- Abstract
Executive function is defined as a set of cognitive skills that are necessary to plan, monitor, and execute a sequence of goal-directed complex actions. Executive function is influenced by a variety of factors, including habitual sleep duration and diabetes. In the present study, we investigated in 18,769 Swedish adults (mean age: 61 y) the association between executive function, diabetes, and self-reported sleep duration. We observed a significant interaction between diabetes and sleep duration for the Trail Making Test (TMT) ratio (P < 0.01). This ratio is a measure of executive function where higher values indicate worse performance. Among diabetic participants (n = 1,523), long (defined as ≥9 h per day) vs. normal sleep duration... (More)
Executive function is defined as a set of cognitive skills that are necessary to plan, monitor, and execute a sequence of goal-directed complex actions. Executive function is influenced by a variety of factors, including habitual sleep duration and diabetes. In the present study, we investigated in 18,769 Swedish adults (mean age: 61 y) the association between executive function, diabetes, and self-reported sleep duration. We observed a significant interaction between diabetes and sleep duration for the Trail Making Test (TMT) ratio (P < 0.01). This ratio is a measure of executive function where higher values indicate worse performance. Among diabetic participants (n = 1,523), long (defined as ≥9 h per day) vs. normal sleep duration (defined as 7–8 hours per day) was associated with a higher TMT ratio (P < 0.05). Similar significant results were observed in diabetic individuals without pharmacological treatment for diabetes (n = 1,062). Among non-diabetic participants (n = 17,246), no association between long sleep duration and the TMT ratio was observed (P > 0.05). Instead, short (defined as <7 h per day) vs. normal sleep duration was linked to a higher TMT ratio (P < 0.05). These findings suggest that the association between sleep duration and executive function differs between diabetic and non-diabetic middle-aged and older adults. Based on the cross-sectional design of the study, no firm conclusions can be drawn on the causality of the relations.
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- author
- Titova, Olga E. ; Lindberg, Eva ; Tan, Xiao ; Elmståhl, Sölve LU ; Lind, Lars ; Schiöth, Helgi B. and Benedict, Christian
- organization
- publishing date
- 2020
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Cohort study, Diabetes, Executive function, Sleep duration
- in
- Psychoneuroendocrinology
- volume
- 111
- article number
- 104472
- publisher
- Elsevier
- external identifiers
-
- scopus:85073016235
- pmid:31610410
- ISSN
- 0306-4530
- DOI
- 10.1016/j.psyneuen.2019.104472
- language
- English
- LU publication?
- yes
- id
- 9f6581f6-9e39-4945-9655-1e61a6d5c401
- date added to LUP
- 2021-01-15 10:33:54
- date last changed
- 2024-09-19 14:57:19
@article{9f6581f6-9e39-4945-9655-1e61a6d5c401, abstract = {{<p>Executive function is defined as a set of cognitive skills that are necessary to plan, monitor, and execute a sequence of goal-directed complex actions. Executive function is influenced by a variety of factors, including habitual sleep duration and diabetes. In the present study, we investigated in 18,769 Swedish adults (mean age: 61 y) the association between executive function, diabetes, and self-reported sleep duration. We observed a significant interaction between diabetes and sleep duration for the Trail Making Test (TMT) ratio (P < 0.01). This ratio is a measure of executive function where higher values indicate worse performance. Among diabetic participants (n = 1,523), long (defined as ≥9 h per day) vs. normal sleep duration (defined as 7–8 hours per day) was associated with a higher TMT ratio (P < 0.05). Similar significant results were observed in diabetic individuals without pharmacological treatment for diabetes (n = 1,062). Among non-diabetic participants (n = 17,246), no association between long sleep duration and the TMT ratio was observed (P > 0.05). Instead, short (defined as <7 h per day) vs. normal sleep duration was linked to a higher TMT ratio (P < 0.05). These findings suggest that the association between sleep duration and executive function differs between diabetic and non-diabetic middle-aged and older adults. Based on the cross-sectional design of the study, no firm conclusions can be drawn on the causality of the relations.</p>}}, author = {{Titova, Olga E. and Lindberg, Eva and Tan, Xiao and Elmståhl, Sölve and Lind, Lars and Schiöth, Helgi B. and Benedict, Christian}}, issn = {{0306-4530}}, keywords = {{Cohort study; Diabetes; Executive function; Sleep duration}}, language = {{eng}}, publisher = {{Elsevier}}, series = {{Psychoneuroendocrinology}}, title = {{Association between sleep duration and executive function differs between diabetic and non-diabetic middle-aged and older adults}}, url = {{http://dx.doi.org/10.1016/j.psyneuen.2019.104472}}, doi = {{10.1016/j.psyneuen.2019.104472}}, volume = {{111}}, year = {{2020}}, }