Patience is the key : Contraceptive induced chorea in a girl with Down Syndrome
(2016) In European Journal of Paediatric Neurology 20(4). p.671-673- Abstract
Background Isolated (sub)acute chorea in young patients is a relatively rare movement disorder with a broad differential diagnosis, including drug-induced, post-infectious, auto-immunological and vascular aetiologies. Case presentation We describe an adolescent girl with Down's syndrome presenting with chorea due to oral contraceptive usage. After discontinuation of the oral contraceptive it took several months before the symptoms disappeared. Although generally well recognised, it is important to realise this delayed effect. Rejecting the diagnosis too soon may lead to unnecessary treatment for other possible underlying aetiologies, especially in patients with Down Syndrome, known to be vulnerable for autoimmune disorders. Conclusion... (More)
Background Isolated (sub)acute chorea in young patients is a relatively rare movement disorder with a broad differential diagnosis, including drug-induced, post-infectious, auto-immunological and vascular aetiologies. Case presentation We describe an adolescent girl with Down's syndrome presenting with chorea due to oral contraceptive usage. After discontinuation of the oral contraceptive it took several months before the symptoms disappeared. Although generally well recognised, it is important to realise this delayed effect. Rejecting the diagnosis too soon may lead to unnecessary treatment for other possible underlying aetiologies, especially in patients with Down Syndrome, known to be vulnerable for autoimmune disorders. Conclusion We plead for discontinuation for at least three months before exclusion of oral contraceptives as cause of chorea.
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- author
- Eggink, Hendriekje ; Kuiper, Anouk ; Delnooz, Cathérine C.S. ; Sival, Deborah A. ; De Koning, Tom J. LU and Tijssen, Marina A.J.
- publishing date
- 2016-07-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Chorea, Down Syndrome, Oral contraceptives
- in
- European Journal of Paediatric Neurology
- volume
- 20
- issue
- 4
- pages
- 3 pages
- publisher
- Elsevier
- external identifiers
-
- scopus:84961903038
- pmid:27053142
- ISSN
- 1090-3798
- DOI
- 10.1016/j.ejpn.2016.03.004
- language
- English
- LU publication?
- no
- id
- 9fb09194-f651-4a65-bc9c-554577f0d9ce
- date added to LUP
- 2020-02-26 09:57:40
- date last changed
- 2024-01-02 06:27:13
@article{9fb09194-f651-4a65-bc9c-554577f0d9ce,
abstract = {{<p>Background Isolated (sub)acute chorea in young patients is a relatively rare movement disorder with a broad differential diagnosis, including drug-induced, post-infectious, auto-immunological and vascular aetiologies. Case presentation We describe an adolescent girl with Down's syndrome presenting with chorea due to oral contraceptive usage. After discontinuation of the oral contraceptive it took several months before the symptoms disappeared. Although generally well recognised, it is important to realise this delayed effect. Rejecting the diagnosis too soon may lead to unnecessary treatment for other possible underlying aetiologies, especially in patients with Down Syndrome, known to be vulnerable for autoimmune disorders. Conclusion We plead for discontinuation for at least three months before exclusion of oral contraceptives as cause of chorea.</p>}},
author = {{Eggink, Hendriekje and Kuiper, Anouk and Delnooz, Cathérine C.S. and Sival, Deborah A. and De Koning, Tom J. and Tijssen, Marina A.J.}},
issn = {{1090-3798}},
keywords = {{Chorea; Down Syndrome; Oral contraceptives}},
language = {{eng}},
month = {{07}},
number = {{4}},
pages = {{671--673}},
publisher = {{Elsevier}},
series = {{European Journal of Paediatric Neurology}},
title = {{Patience is the key : Contraceptive induced chorea in a girl with Down Syndrome}},
url = {{http://dx.doi.org/10.1016/j.ejpn.2016.03.004}},
doi = {{10.1016/j.ejpn.2016.03.004}},
volume = {{20}},
year = {{2016}},
}