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Body mass index and weight gain in pregnancy and cardiovascular health in middle age : A cohort study

Waagaard, Lovisa ; Herraiz-Adillo, Ángel ; Ahlqvist, Viktor H. ; Higueras-Fresnillo, Sara ; Berglind, Daniel ; Wennberg, Patrik ; Daka, Bledar ; Lenander, Cecilia LU ; Sundström, Johan and Östgren, Carl Johan , et al. (2023) In BJOG: An International Journal of Obstetrics and Gynaecology
Abstract

Objective: To examine associations between body mass index (BMI) in early pregnancy and gestational weight gain (GWG) with cardiovascular health in middle age using the ‘Life's Essential 8’ (LE8) concept of the American Heart Association (AHA). Design: Population-based cohort study. Setting: Swedish CardioPulmonary bioImage Study (SCAPIS). Population: A total of 8871 women from SCAPIS were included. Methods: Information on cardiovascular health in middle age was collected from SCAPIS and linked to pregnancy weight data obtained from the Swedish Medical Birth Register, with an average follow-up time of 24.5 years. An LE8 score between 0 and 100 was determined, where a score under 60 points was defined as poor cardiovascular health.... (More)

Objective: To examine associations between body mass index (BMI) in early pregnancy and gestational weight gain (GWG) with cardiovascular health in middle age using the ‘Life's Essential 8’ (LE8) concept of the American Heart Association (AHA). Design: Population-based cohort study. Setting: Swedish CardioPulmonary bioImage Study (SCAPIS). Population: A total of 8871 women from SCAPIS were included. Methods: Information on cardiovascular health in middle age was collected from SCAPIS and linked to pregnancy weight data obtained from the Swedish Medical Birth Register, with an average follow-up time of 24.5 years. An LE8 score between 0 and 100 was determined, where a score under 60 points was defined as poor cardiovascular health. Binary logistic regression and restricted cubic splines were used. Main outcome measures: Cardiovascular health according to LE8 in middle age. Results: The odds of having poor cardiovascular health in middle age were significantly higher in women who had overweight (adjusted odds ratio, aOR 3.30, 95% CI 2.82–3.88) or obesity (aOR 7.63, 95% CI 5.86–9.94), compared with women classified as being of normal weight in pregnancy. Higher odds were also found for excessive GWG (aOR 1.31, 95% CI 1.09–1.57), compared with women who gained weight within the recommendations. Conclusions: A high BMI in early pregnancy and excessive GWG were associated with greater odds of poor cardiovascular health in middle age. Although further studies are needed, our results highlight pregnancy as an important period to support long-term cardiovascular health.

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organization
publishing date
type
Contribution to journal
publication status
epub
subject
keywords
body mass index, gestational weight gain, Life's Essential 8, pregnancy, pregnancy as a window for future health
in
BJOG: An International Journal of Obstetrics and Gynaecology
publisher
Wiley-Blackwell
external identifiers
  • pmid:38149523
  • scopus:85180848848
ISSN
1470-0328
DOI
10.1111/1471-0528.17740
language
English
LU publication?
yes
id
a0d762ff-73a4-4277-98de-79a955e492d5
date added to LUP
2024-01-31 14:31:33
date last changed
2024-04-17 02:46:29
@article{a0d762ff-73a4-4277-98de-79a955e492d5,
  abstract     = {{<p>Objective: To examine associations between body mass index (BMI) in early pregnancy and gestational weight gain (GWG) with cardiovascular health in middle age using the ‘Life's Essential 8’ (LE8) concept of the American Heart Association (AHA). Design: Population-based cohort study. Setting: Swedish CardioPulmonary bioImage Study (SCAPIS). Population: A total of 8871 women from SCAPIS were included. Methods: Information on cardiovascular health in middle age was collected from SCAPIS and linked to pregnancy weight data obtained from the Swedish Medical Birth Register, with an average follow-up time of 24.5 years. An LE8 score between 0 and 100 was determined, where a score under 60 points was defined as poor cardiovascular health. Binary logistic regression and restricted cubic splines were used. Main outcome measures: Cardiovascular health according to LE8 in middle age. Results: The odds of having poor cardiovascular health in middle age were significantly higher in women who had overweight (adjusted odds ratio, aOR 3.30, 95% CI 2.82–3.88) or obesity (aOR 7.63, 95% CI 5.86–9.94), compared with women classified as being of normal weight in pregnancy. Higher odds were also found for excessive GWG (aOR 1.31, 95% CI 1.09–1.57), compared with women who gained weight within the recommendations. Conclusions: A high BMI in early pregnancy and excessive GWG were associated with greater odds of poor cardiovascular health in middle age. Although further studies are needed, our results highlight pregnancy as an important period to support long-term cardiovascular health.</p>}},
  author       = {{Waagaard, Lovisa and Herraiz-Adillo, Ángel and Ahlqvist, Viktor H. and Higueras-Fresnillo, Sara and Berglind, Daniel and Wennberg, Patrik and Daka, Bledar and Lenander, Cecilia and Sundström, Johan and Östgren, Carl Johan and Rådholm, Karin and Henriksson, Pontus}},
  issn         = {{1470-0328}},
  keywords     = {{body mass index; gestational weight gain; Life's Essential 8; pregnancy; pregnancy as a window for future health}},
  language     = {{eng}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{BJOG: An International Journal of Obstetrics and Gynaecology}},
  title        = {{Body mass index and weight gain in pregnancy and cardiovascular health in middle age : A cohort study}},
  url          = {{http://dx.doi.org/10.1111/1471-0528.17740}},
  doi          = {{10.1111/1471-0528.17740}},
  year         = {{2023}},
}