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Epistatic mutations under divergent selection govern phenotypic variation in the crow hybrid zone

Knief, Ulrich; Bossu, Christen M.; Saino, Nicola; Hansson, Bengt LU ; Poelstra, Jelmer; Vijay, Nagarjun; Weissensteiner, Matthias and Wolf, Jochen B.W. (2019) In Nature Ecology and Evolution 3(4). p.570-576
Abstract

The evolution of genetic barriers opposing interspecific gene flow is key to the origin of new species. Drawing from information on over 400 admixed genomes sourced from replicate transects across the European hybrid zone between all-black carrion crows and grey-coated hooded crows, we decipher the interplay between phenotypic divergence and selection at the molecular level. Over 68% of plumage variation was explained by epistasis between the gene NDP and a ~2.8-megabase region on chromosome 18 with suppressed recombination. Both pigmentation loci showed evidence for divergent selection resisting introgression. This study reveals how few, large-effect loci can govern prezygotic isolation and shield phenotypic divergence from gene... (More)

The evolution of genetic barriers opposing interspecific gene flow is key to the origin of new species. Drawing from information on over 400 admixed genomes sourced from replicate transects across the European hybrid zone between all-black carrion crows and grey-coated hooded crows, we decipher the interplay between phenotypic divergence and selection at the molecular level. Over 68% of plumage variation was explained by epistasis between the gene NDP and a ~2.8-megabase region on chromosome 18 with suppressed recombination. Both pigmentation loci showed evidence for divergent selection resisting introgression. This study reveals how few, large-effect loci can govern prezygotic isolation and shield phenotypic divergence from gene flow.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Nature Ecology and Evolution
volume
3
issue
4
pages
7 pages
publisher
Nature Publishing Group
external identifiers
  • scopus:85063576944
DOI
10.1038/s41559-019-0847-9
language
English
LU publication?
yes
id
a209f52c-05b9-42df-a35e-ac88697072e6
date added to LUP
2019-04-09 14:07:03
date last changed
2019-06-26 02:20:59
@article{a209f52c-05b9-42df-a35e-ac88697072e6,
  abstract     = {<p>The evolution of genetic barriers opposing interspecific gene flow is key to the origin of new species. Drawing from information on over 400 admixed genomes sourced from replicate transects across the European hybrid zone between all-black carrion crows and grey-coated hooded crows, we decipher the interplay between phenotypic divergence and selection at the molecular level. Over 68% of plumage variation was explained by epistasis between the gene NDP and a ~2.8-megabase region on chromosome 18 with suppressed recombination. Both pigmentation loci showed evidence for divergent selection resisting introgression. This study reveals how few, large-effect loci can govern prezygotic isolation and shield phenotypic divergence from gene flow.</p>},
  author       = {Knief, Ulrich and Bossu, Christen M. and Saino, Nicola and Hansson, Bengt and Poelstra, Jelmer and Vijay, Nagarjun and Weissensteiner, Matthias and Wolf, Jochen B.W.},
  language     = {eng},
  number       = {4},
  pages        = {570--576},
  publisher    = {Nature Publishing Group},
  series       = {Nature Ecology and Evolution},
  title        = {Epistatic mutations under divergent selection govern phenotypic variation in the crow hybrid zone},
  url          = {http://dx.doi.org/10.1038/s41559-019-0847-9},
  volume       = {3},
  year         = {2019},
}