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DIAGNOSIS OF ENDOCRINE DISEASE : Sex steroid action in adolescence: too much, too little; too early, too late

Hansen, A. B. ; Wøjdemann, D. ; Renault, C. H. ; Pedersen, A. T. ; Main, K. M. ; Raket, L. L. LU ; Jensen, R. B. and Juul, A. (2021) In European Journal of Endocrinology 184(1). p.17-28
Abstract

Abstract: This review aims to cover the subject of sex steroid action in adolescence. It will include situations with too little sex steroid action, as seen in for example, Turners syndrome and androgen insensitivity issues, too much sex steroid action as seen in adolescent PCOS, CAH and gynecomastia, too late sex steroid action as seen in constitutional delay of growth and puberty and too early sex steroid action as seen in precocious puberty. This review will cover the etiology, the signs and symptoms which the clinician should be attentive to, important differential diagnoses to know and be able to distinguish, long-term health and social consequences of these hormonal disorders and the course of action with regards to medical... (More)

Abstract: This review aims to cover the subject of sex steroid action in adolescence. It will include situations with too little sex steroid action, as seen in for example, Turners syndrome and androgen insensitivity issues, too much sex steroid action as seen in adolescent PCOS, CAH and gynecomastia, too late sex steroid action as seen in constitutional delay of growth and puberty and too early sex steroid action as seen in precocious puberty. This review will cover the etiology, the signs and symptoms which the clinician should be attentive to, important differential diagnoses to know and be able to distinguish, long-term health and social consequences of these hormonal disorders and the course of action with regards to medical treatment in the pediatric endocrinological department and for the general practitioner. This review also covers situations with exogenous sex steroid application for therapeutic purposes in the adolescent and young adult. This includes gender-affirming therapy in the transgender child and hormone treatment of tall statured children. It gives some background information of the cause of treatment, the patient's motivation for medicating (or self-medicating), long-term consequences of exogenous sex steroid treatment and clinical outcome of this treatment.

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author
; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
European Journal of Endocrinology
volume
184
issue
1
pages
17 - 28
publisher
Society of the European Journal of Endocrinology
external identifiers
  • pmid:33112274
  • scopus:85096080018
ISSN
1479-683X
DOI
10.1530/EJE-20-0545
language
English
LU publication?
yes
id
a39c73f1-a7c0-4b16-bbfe-d67de5dd683b
date added to LUP
2020-12-08 13:39:14
date last changed
2024-03-20 20:21:55
@article{a39c73f1-a7c0-4b16-bbfe-d67de5dd683b,
  abstract     = {{<p>Abstract: This review aims to cover the subject of sex steroid action in adolescence. It will include situations with too little sex steroid action, as seen in for example, Turners syndrome and androgen insensitivity issues, too much sex steroid action as seen in adolescent PCOS, CAH and gynecomastia, too late sex steroid action as seen in constitutional delay of growth and puberty and too early sex steroid action as seen in precocious puberty. This review will cover the etiology, the signs and symptoms which the clinician should be attentive to, important differential diagnoses to know and be able to distinguish, long-term health and social consequences of these hormonal disorders and the course of action with regards to medical treatment in the pediatric endocrinological department and for the general practitioner. This review also covers situations with exogenous sex steroid application for therapeutic purposes in the adolescent and young adult. This includes gender-affirming therapy in the transgender child and hormone treatment of tall statured children. It gives some background information of the cause of treatment, the patient's motivation for medicating (or self-medicating), long-term consequences of exogenous sex steroid treatment and clinical outcome of this treatment.</p>}},
  author       = {{Hansen, A. B. and Wøjdemann, D. and Renault, C. H. and Pedersen, A. T. and Main, K. M. and Raket, L. L. and Jensen, R. B. and Juul, A.}},
  issn         = {{1479-683X}},
  language     = {{eng}},
  month        = {{01}},
  number       = {{1}},
  pages        = {{17--28}},
  publisher    = {{Society of the European Journal of Endocrinology}},
  series       = {{European Journal of Endocrinology}},
  title        = {{DIAGNOSIS OF ENDOCRINE DISEASE : Sex steroid action in adolescence: too much, too little; too early, too late}},
  url          = {{http://dx.doi.org/10.1530/EJE-20-0545}},
  doi          = {{10.1530/EJE-20-0545}},
  volume       = {{184}},
  year         = {{2021}},
}