Treatment Utilisation and Satisfaction With Management in Individuals With Osteoarthritis and Metabolic Multimorbidity : A Cross-Sectional Multi-Country Study
Recenti, Filippo LU ; Dell'isola, Andrea LU ; Giardulli, Benedetto ; Testa, Marco ; Pchelnikova, Polina ; Ndosi, Mwidimi and Battista, Simone LU
(2025)
In Musculoskeletal Care
23(1).
- Abstract
Purpose: To compare treatment utilisation for osteoarthritis (OA) and satisfaction with OA management between individuals with and without comorbid metabolic conditions (e.g., diabetes, obesity, dyslipidaemia, hypertension). Methods: Secondary analysis of a cross-sectional international survey study (Italy, Russia, Sweden) on people ≥ 40 years old with knee/hip OA. Metabolic comorbidity was self-reported. We used direct standardisation with prevalence ratios and mixed-effect models to estimate the associations between comorbidity with treatment utilisation and satisfaction (score 0–100). Results: We analysed 401 individuals (48% Sweden, 28% Italy, 24% Russia; 53% with ≥ 1 metabolic condition). Those with and without comorbid metabolic... (More)
Purpose: To compare treatment utilisation for osteoarthritis (OA) and satisfaction with OA management between individuals with and without comorbid metabolic conditions (e.g., diabetes, obesity, dyslipidaemia, hypertension). Methods: Secondary analysis of a cross-sectional international survey study (Italy, Russia, Sweden) on people ≥ 40 years old with knee/hip OA. Metabolic comorbidity was self-reported. We used direct standardisation with prevalence ratios and mixed-effect models to estimate the associations between comorbidity with treatment utilisation and satisfaction (score 0–100). Results: We analysed 401 individuals (48% Sweden, 28% Italy, 24% Russia; 53% with ≥ 1 metabolic condition). Those with and without comorbid metabolic conditions showed similar prevalence for first-line interventions (exercise, education, and weight management). Metabolically unhealthy individuals showed higher use of opioids (prevalence ratio [95% CI] 1.9 [1.3–2.4]), antidepressants (1.8 [1.1–2.5]), corticosteroid injections (1.4 [1.0−1.8]), and homoeopathic products (2.1 [1.2–3.0]). Satisfaction with care (adjusted difference: −3.9 [95% CI: −8.5 to 2.4]) and information received about treatments (−4.0 [−9.7 to 1.7]) were similar. Conclusions: While first-line OA interventions were similarly used, those with metabolic conditions relied more on second-line and non-recommended treatments, showing comparable satisfaction. More effort is needed to increase the adoption of lifestyle-focused treatments in OA and to minimise the use of less recommended options among individuals with metabolic comorbidities.
(Less)
- author
- Recenti, Filippo
LU
; Dell'isola, Andrea
LU
; Giardulli, Benedetto
; Testa, Marco
; Pchelnikova, Polina
; Ndosi, Mwidimi
and Battista, Simone
LU
- organization
- publishing date
- 2025
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- comorbidity, consumer experience, diabetes, healthcare consumption, hypertension, obesity, osteoarthritis
- in
- Musculoskeletal Care
- volume
- 23
- issue
- 1
- article number
- e70058
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:85215953369
- pmid:39853636
- ISSN
- 1478-2189
- DOI
- 10.1002/msc.70058
- language
- English
- LU publication?
- yes
- id
- a440cea4-692c-4e14-aed5-5358b7880f77
- date added to LUP
- 2025-03-24 10:25:10
- date last changed
- 2025-07-14 17:04:29
@article{a440cea4-692c-4e14-aed5-5358b7880f77,
abstract = {{<p>Purpose: To compare treatment utilisation for osteoarthritis (OA) and satisfaction with OA management between individuals with and without comorbid metabolic conditions (e.g., diabetes, obesity, dyslipidaemia, hypertension). Methods: Secondary analysis of a cross-sectional international survey study (Italy, Russia, Sweden) on people ≥ 40 years old with knee/hip OA. Metabolic comorbidity was self-reported. We used direct standardisation with prevalence ratios and mixed-effect models to estimate the associations between comorbidity with treatment utilisation and satisfaction (score 0–100). Results: We analysed 401 individuals (48% Sweden, 28% Italy, 24% Russia; 53% with ≥ 1 metabolic condition). Those with and without comorbid metabolic conditions showed similar prevalence for first-line interventions (exercise, education, and weight management). Metabolically unhealthy individuals showed higher use of opioids (prevalence ratio [95% CI] 1.9 [1.3–2.4]), antidepressants (1.8 [1.1–2.5]), corticosteroid injections (1.4 [1.0−1.8]), and homoeopathic products (2.1 [1.2–3.0]). Satisfaction with care (adjusted difference: −3.9 [95% CI: −8.5 to 2.4]) and information received about treatments (−4.0 [−9.7 to 1.7]) were similar. Conclusions: While first-line OA interventions were similarly used, those with metabolic conditions relied more on second-line and non-recommended treatments, showing comparable satisfaction. More effort is needed to increase the adoption of lifestyle-focused treatments in OA and to minimise the use of less recommended options among individuals with metabolic comorbidities.</p>}},
author = {{Recenti, Filippo and Dell'isola, Andrea and Giardulli, Benedetto and Testa, Marco and Pchelnikova, Polina and Ndosi, Mwidimi and Battista, Simone}},
issn = {{1478-2189}},
keywords = {{comorbidity; consumer experience; diabetes; healthcare consumption; hypertension; obesity; osteoarthritis}},
language = {{eng}},
number = {{1}},
publisher = {{Wiley-Blackwell}},
series = {{Musculoskeletal Care}},
title = {{Treatment Utilisation and Satisfaction With Management in Individuals With Osteoarthritis and Metabolic Multimorbidity : A Cross-Sectional Multi-Country Study}},
url = {{http://dx.doi.org/10.1002/msc.70058}},
doi = {{10.1002/msc.70058}},
volume = {{23}},
year = {{2025}},
}