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Components and Biological Activities of Venom from Lionfishes (Scorpaenidae: Pterois)

Rodriguez, Candelario ; Carrasco, Jafeth LU ; Bruner-Montero, Gaspar ; Pires Júnior, Osmindo Rodrigues ; Gutiérrez, Marcelino and Díaz-Ferguson, Edgardo (2025) In Marine Drugs 23(2). p.1-15
Abstract

Fishes of the genus
Pterois possess spines that provoke intense pain, which can last for weeks. Since the first toxicological description of their spine venom, a significant amount of research has been published regarding their biochemical characterization. This minireview presents research published from 1959 to 2024 on bioactive substances found in
Pterois species.
Pterois venom mainly contains peptides and proteins that display a range of biological activities, including anticancer, antimicrobial, antioxidant, antiviral, enzymatic, cardiovascular, procoagulant, neurological, neuromuscular, and nutraceutical effects. Although
Pterois venom contains bioactive substances, the toxic side effects, such as hemolysis... (More)

Fishes of the genus
Pterois possess spines that provoke intense pain, which can last for weeks. Since the first toxicological description of their spine venom, a significant amount of research has been published regarding their biochemical characterization. This minireview presents research published from 1959 to 2024 on bioactive substances found in
Pterois species.
Pterois venom mainly contains peptides and proteins that display a range of biological activities, including anticancer, antimicrobial, antioxidant, antiviral, enzymatic, cardiovascular, procoagulant, neurological, neuromuscular, and nutraceutical effects. Although
Pterois venom contains bioactive substances, the toxic side effects, such as hemolysis and nociception, of these venoms should be considered. Hence, further intense research is needed to establish the potential uses of
Pterois venom for human health.

(Less)
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author
; ; ; ; and
publishing date
type
Contribution to journal
publication status
published
keywords
Animals, Fish Venoms/chemistry, Humans, Perciformes, Peptides/pharmacology, Anti-Infective Agents/pharmacology, Antioxidants/pharmacology
in
Marine Drugs
volume
23
issue
2
article number
55
pages
1 - 15
publisher
MDPI AG
external identifiers
  • pmid:39997179
  • scopus:85219175728
ISSN
1660-3397
DOI
10.3390/md23020055
language
English
LU publication?
no
id
a4eb3b6e-23af-4b2d-9dd2-e5e1880d43b8
date added to LUP
2026-01-29 10:17:32
date last changed
2026-01-30 04:01:48
@article{a4eb3b6e-23af-4b2d-9dd2-e5e1880d43b8,
  abstract     = {{<p>Fishes of the genus <br>
 Pterois possess spines that provoke intense pain, which can last for weeks. Since the first toxicological description of their spine venom, a significant amount of research has been published regarding their biochemical characterization. This minireview presents research published from 1959 to 2024 on bioactive substances found in <br>
 Pterois species. <br>
 Pterois venom mainly contains peptides and proteins that display a range of biological activities, including anticancer, antimicrobial, antioxidant, antiviral, enzymatic, cardiovascular, procoagulant, neurological, neuromuscular, and nutraceutical effects. Although <br>
 Pterois venom contains bioactive substances, the toxic side effects, such as hemolysis and nociception, of these venoms should be considered. Hence, further intense research is needed to establish the potential uses of<br>
 Pterois venom for human health.<br>
 </p>}},
  author       = {{Rodriguez, Candelario and Carrasco, Jafeth and Bruner-Montero, Gaspar and Pires Júnior, Osmindo Rodrigues and Gutiérrez, Marcelino and Díaz-Ferguson, Edgardo}},
  issn         = {{1660-3397}},
  keywords     = {{Animals; Fish Venoms/chemistry; Humans; Perciformes; Peptides/pharmacology; Anti-Infective Agents/pharmacology; Antioxidants/pharmacology}},
  language     = {{eng}},
  month        = {{01}},
  number       = {{2}},
  pages        = {{1--15}},
  publisher    = {{MDPI AG}},
  series       = {{Marine Drugs}},
  title        = {{Components and Biological Activities of Venom from Lionfishes (Scorpaenidae: Pterois)}},
  url          = {{http://dx.doi.org/10.3390/md23020055}},
  doi          = {{10.3390/md23020055}},
  volume       = {{23}},
  year         = {{2025}},
}