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Short review : Air pollution, noise and lack of greenness as risk factors for Alzheimer's disease- epidemiologic and experimental evidence

Oudin, Anna LU (2020) In Neurochemistry International 134.
Abstract

The number of patients with Alzheimer's disease (AD) is likely to triple in a few decades as the world's population ages. Given the high personal and societal burden of this disease, it is imperative to identify its risk factors. The etiology of AD is still not fully understood, but environmental factors have emerged as plausible important risk factors on the population-level. In this short review, the author summarizes literature on air pollution, noise and (lack of) greenness as risk factors for AD. In conclusion, a link between air pollution and AD is supported by experimental studies as well as epidemiological studies, although a multi-exposure approach is lacking in most epidemiological studies. Although evidence is much more... (More)

The number of patients with Alzheimer's disease (AD) is likely to triple in a few decades as the world's population ages. Given the high personal and societal burden of this disease, it is imperative to identify its risk factors. The etiology of AD is still not fully understood, but environmental factors have emerged as plausible important risk factors on the population-level. In this short review, the author summarizes literature on air pollution, noise and (lack of) greenness as risk factors for AD. In conclusion, a link between air pollution and AD is supported by experimental studies as well as epidemiological studies, although a multi-exposure approach is lacking in most epidemiological studies. Although evidence is much more limited regarding noise and (lack of) greenness as risk factors for AD, future epidemiological studies should have a multi-exposure approach in order to separate potential effects of air pollution, noise and lack of greenness. Given the heavy toll of AD on individuals and society, as well as the ubiquitous nature of environmental factors, a link between environmental stressors and AD deserves special attention.

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Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Air pollution, Alzheimer's, Cognitive disorders, Dementia, Greenness, Noise, Traffic
in
Neurochemistry International
volume
134
article number
104646
publisher
Elsevier
external identifiers
  • pmid:31866324
  • scopus:85077732194
ISSN
0197-0186
DOI
10.1016/j.neuint.2019.104646
language
English
LU publication?
yes
id
a513f880-2663-48dc-abdb-b6b890ad13b4
date added to LUP
2020-01-23 11:08:55
date last changed
2024-04-03 00:19:35
@article{a513f880-2663-48dc-abdb-b6b890ad13b4,
  abstract     = {{<p>The number of patients with Alzheimer's disease (AD) is likely to triple in a few decades as the world's population ages. Given the high personal and societal burden of this disease, it is imperative to identify its risk factors. The etiology of AD is still not fully understood, but environmental factors have emerged as plausible important risk factors on the population-level. In this short review, the author summarizes literature on air pollution, noise and (lack of) greenness as risk factors for AD. In conclusion, a link between air pollution and AD is supported by experimental studies as well as epidemiological studies, although a multi-exposure approach is lacking in most epidemiological studies. Although evidence is much more limited regarding noise and (lack of) greenness as risk factors for AD, future epidemiological studies should have a multi-exposure approach in order to separate potential effects of air pollution, noise and lack of greenness. Given the heavy toll of AD on individuals and society, as well as the ubiquitous nature of environmental factors, a link between environmental stressors and AD deserves special attention.</p>}},
  author       = {{Oudin, Anna}},
  issn         = {{0197-0186}},
  keywords     = {{Air pollution; Alzheimer's; Cognitive disorders; Dementia; Greenness; Noise; Traffic}},
  language     = {{eng}},
  publisher    = {{Elsevier}},
  series       = {{Neurochemistry International}},
  title        = {{Short review : Air pollution, noise and lack of greenness as risk factors for Alzheimer's disease- epidemiologic and experimental evidence}},
  url          = {{http://dx.doi.org/10.1016/j.neuint.2019.104646}},
  doi          = {{10.1016/j.neuint.2019.104646}},
  volume       = {{134}},
  year         = {{2020}},
}