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Tender points as predictors of distress and the pharmacologic management of fibromyalgia syndrome

McCarberg, Bill; Barkin, Robert L; Wright, Julie A; Cronan, Terry A; Groessl, Erik and Schmidt, Steven M LU (2003) In American Journal of Therapeutics 10(3). p.92-176
Abstract

The object of this study was to determine the association between tender point pain ratings, tender point counts and distress in people with fibromyalgia and to review the pharmacotherapy of fibromyalgia. Demographic, psychosocial, and health status information was collected from 316 health maintenance organization members with fibromyalgia. A manual tender point exam was conducted. Tender point counts predicted 3.0%, and tender point severity ratings predicted 8.3%, of the variance in distress. Little difference was found between the variance predicted for physical versus psychologic distress. A principal components analysis of all measures produced four distinct factors: global-physical functioning, tender points, psychologic, and... (More)

The object of this study was to determine the association between tender point pain ratings, tender point counts and distress in people with fibromyalgia and to review the pharmacotherapy of fibromyalgia. Demographic, psychosocial, and health status information was collected from 316 health maintenance organization members with fibromyalgia. A manual tender point exam was conducted. Tender point counts predicted 3.0%, and tender point severity ratings predicted 8.3%, of the variance in distress. Little difference was found between the variance predicted for physical versus psychologic distress. A principal components analysis of all measures produced four distinct factors: global-physical functioning, tender points, psychologic, and physical. Tender point pain ratings and counts predicted a small but significant amount of variance in distress. In addition, FMS involves at least four rather distinct factors, one of which is related to tender points. Pharmacotherapeutic management is provided on a patient-specific basis including pharmacokinetics, pharmacodynamic, pathophysiologic, and psychosocial needs designed and modulated for each individual patient.

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author
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Contribution to journal
publication status
published
keywords
Adult, Aged, Analgesics, Antidepressive Agents, Cyclooxygenase Inhibitors, Female, Fibromyalgia, Humans, Middle Aged, Pain, Pain Measurement, Pain Threshold, Palpation, Receptors, Serotonin, Reproducibility of Results, Serotonin Antagonists, Severity of Illness Index, Surveys and Questionnaires, United States, Journal Article
in
American Journal of Therapeutics
volume
10
issue
3
pages
17 pages
publisher
Lippincott Williams & Wilkins
external identifiers
  • scopus:0141765778
ISSN
1075-2765
language
English
LU publication?
no
id
a62e81e9-cf36-4c9d-9846-ff7c36ef63cb
date added to LUP
2017-03-08 12:09:45
date last changed
2017-03-13 11:31:20
@article{a62e81e9-cf36-4c9d-9846-ff7c36ef63cb,
  abstract     = {<p>The object of this study was to determine the association between tender point pain ratings, tender point counts and distress in people with fibromyalgia and to review the pharmacotherapy of fibromyalgia. Demographic, psychosocial, and health status information was collected from 316 health maintenance organization members with fibromyalgia. A manual tender point exam was conducted. Tender point counts predicted 3.0%, and tender point severity ratings predicted 8.3%, of the variance in distress. Little difference was found between the variance predicted for physical versus psychologic distress. A principal components analysis of all measures produced four distinct factors: global-physical functioning, tender points, psychologic, and physical. Tender point pain ratings and counts predicted a small but significant amount of variance in distress. In addition, FMS involves at least four rather distinct factors, one of which is related to tender points. Pharmacotherapeutic management is provided on a patient-specific basis including pharmacokinetics, pharmacodynamic, pathophysiologic, and psychosocial needs designed and modulated for each individual patient.</p>},
  author       = {McCarberg, Bill and Barkin, Robert L and Wright, Julie A and Cronan, Terry A and Groessl, Erik and Schmidt, Steven M},
  issn         = {1075-2765},
  keyword      = {Adult,Aged,Analgesics,Antidepressive Agents,Cyclooxygenase Inhibitors,Female,Fibromyalgia,Humans,Middle Aged,Pain,Pain Measurement,Pain Threshold,Palpation,Receptors, Serotonin,Reproducibility of Results,Serotonin Antagonists,Severity of Illness Index,Surveys and Questionnaires,United States,Journal Article},
  language     = {eng},
  month        = {05},
  number       = {3},
  pages        = {92--176},
  publisher    = {Lippincott Williams & Wilkins},
  series       = {American Journal of Therapeutics},
  title        = {Tender points as predictors of distress and the pharmacologic management of fibromyalgia syndrome},
  volume       = {10},
  year         = {2003},
}