Expression and Prognostic Significance of Human Epidermal Growth Factor Receptors 1 and 3 in Gastric and Esophageal Adenocarcinoma.
(2016) In PLoS ONE 11(2).- Abstract
- Gastric and esophageal adenocarcinomas are major global cancer burdens. These cancer forms are characterized by a poor prognosis and a modest response to chemo- radio- and targeted treatment. Hence there is an obvious need for further enhanced diagnostic and treatment strategies. The aim of this study was to examine the expression and prognostic impact of human epidermal growth factor receptor 1 (HER1/EGFR) and 3 (HER3), as well as the occurrence of EGFR and KRAS mutations in gastric and esophageal adenocarcinoma.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8829316
- author
- Hedner, Charlotta LU ; Borg, David LU ; Nodin, Björn LU ; Karnevi, Emelie LU ; Jirström, Karin LU and Eberhard, Jakob LU
- organization
- publishing date
- 2016
- type
- Contribution to journal
- publication status
- published
- subject
- in
- PLoS ONE
- volume
- 11
- issue
- 2
- article number
- e0148101
- publisher
- Public Library of Science (PLoS)
- external identifiers
-
- pmid:26844548
- scopus:84959018090
- wos:000369552800029
- pmid:26844548
- ISSN
- 1932-6203
- DOI
- 10.1371/journal.pone.0148101
- language
- English
- LU publication?
- yes
- id
- a69dc566-dbb0-4981-844c-04f1d745919e (old id 8829316)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26844548?dopt=Abstract
- date added to LUP
- 2016-04-01 12:54:31
- date last changed
- 2024-01-09 04:49:51
@article{a69dc566-dbb0-4981-844c-04f1d745919e, abstract = {{Gastric and esophageal adenocarcinomas are major global cancer burdens. These cancer forms are characterized by a poor prognosis and a modest response to chemo- radio- and targeted treatment. Hence there is an obvious need for further enhanced diagnostic and treatment strategies. The aim of this study was to examine the expression and prognostic impact of human epidermal growth factor receptor 1 (HER1/EGFR) and 3 (HER3), as well as the occurrence of EGFR and KRAS mutations in gastric and esophageal adenocarcinoma.}}, author = {{Hedner, Charlotta and Borg, David and Nodin, Björn and Karnevi, Emelie and Jirström, Karin and Eberhard, Jakob}}, issn = {{1932-6203}}, language = {{eng}}, number = {{2}}, publisher = {{Public Library of Science (PLoS)}}, series = {{PLoS ONE}}, title = {{Expression and Prognostic Significance of Human Epidermal Growth Factor Receptors 1 and 3 in Gastric and Esophageal Adenocarcinoma.}}, url = {{http://dx.doi.org/10.1371/journal.pone.0148101}}, doi = {{10.1371/journal.pone.0148101}}, volume = {{11}}, year = {{2016}}, }