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The Correlation of Polymorphism of Estrogen Receptor Gene to Dry Eye Syndrome in Postmenopausal Women

He, Yanling ; Li,, Xiaoxin ; Bao,, Yongzhen ; Sun, Jianmin LU and Liu, Jinrong (2006) In Yanke xuebao (Visual Science) 22(4). p.233-236
Abstract
PURPOSE: To investigate the correlation of estrogen receptor (ER) gene polymorphism to dry eye syndrome in postmenopausal women. METHODS: Xba I and Pvu II polymorphism of ER gene were studied by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) in 65 patients with dry eye syndrome and 73 with controls in postmenopausal women. RESULTS: There was a significant difference of Pvu II polymorphism of ER gene between the patients of dry eye syndrome and controls in postmenopausal women (P < 0.05), but no significant difference was found in Xba I polymorphism of ER gene (P > 0.05). CONCLUSION: There is a significant correlation of Pvu II polymorphism of ER gene with dry eye syndrome in postmenopausal women. It is... (More)
PURPOSE: To investigate the correlation of estrogen receptor (ER) gene polymorphism to dry eye syndrome in postmenopausal women. METHODS: Xba I and Pvu II polymorphism of ER gene were studied by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) in 65 patients with dry eye syndrome and 73 with controls in postmenopausal women. RESULTS: There was a significant difference of Pvu II polymorphism of ER gene between the patients of dry eye syndrome and controls in postmenopausal women (P < 0.05), but no significant difference was found in Xba I polymorphism of ER gene (P > 0.05). CONCLUSION: There is a significant correlation of Pvu II polymorphism of ER gene with dry eye syndrome in postmenopausal women. It is indicated that the difference in ER genotypes might influence the development of dry eye syndrome. (Less)
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author
; ; ; and
publishing date
type
Contribution to journal
publication status
published
subject
in
Yanke xuebao (Visual Science)
volume
22
issue
4
pages
233 - 236
publisher
Zhongshan Yike Daxue Zhongshan Yanke Zhongxin
external identifiers
  • pmid:17378156
  • scopus:45749128737
ISSN
1000-4432
language
Chinese
LU publication?
no
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Experimental Clinical Chemistry (013016010)
id
a6fb327b-94b1-4972-ade7-881f4d02f889 (old id 1137436)
date added to LUP
2016-04-01 15:53:31
date last changed
2022-01-28 07:49:37
@article{a6fb327b-94b1-4972-ade7-881f4d02f889,
  abstract     = {{PURPOSE: To investigate the correlation of estrogen receptor (ER) gene polymorphism to dry eye syndrome in postmenopausal women. METHODS: Xba I and Pvu II polymorphism of ER gene were studied by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) in 65 patients with dry eye syndrome and 73 with controls in postmenopausal women. RESULTS: There was a significant difference of Pvu II polymorphism of ER gene between the patients of dry eye syndrome and controls in postmenopausal women (P &lt; 0.05), but no significant difference was found in Xba I polymorphism of ER gene (P &gt; 0.05). CONCLUSION: There is a significant correlation of Pvu II polymorphism of ER gene with dry eye syndrome in postmenopausal women. It is indicated that the difference in ER genotypes might influence the development of dry eye syndrome.}},
  author       = {{He, Yanling and Li,, Xiaoxin and Bao,, Yongzhen and Sun, Jianmin and Liu, Jinrong}},
  issn         = {{1000-4432}},
  language     = {{chi}},
  number       = {{4}},
  pages        = {{233--236}},
  publisher    = {{Zhongshan Yike Daxue Zhongshan Yanke Zhongxin}},
  series       = {{Yanke xuebao (Visual Science)}},
  title        = {{The Correlation of Polymorphism of Estrogen Receptor Gene to Dry Eye Syndrome in Postmenopausal Women}},
  volume       = {{22}},
  year         = {{2006}},
}