Unmasking Gastroparesis in Diabetes During Ramadan : Challenges and Management Strategies
Abdulrasak, Mohammed LU
; Shaat, Nael
LU
; Someili, Ali M
and Mohrag, Mostafa
(2025)
In Journal of Clinical Medicine
14(6).
p.1-12
- Abstract
Gastroparesis, characterized by delayed gastric emptying without mechanical obstruction, is a recognized complication of long-standing diabetes. Its pathophysiology involves, amongst other mechanisms, autonomic dysfunction due to vagal nerve damage, impaired smooth muscle contractility, and hormonal dysregulation of intestinal motility. During Ramadan, fasting causes significant dietary changes due to prolonged fasting and the consumption of large meals for Iftar (breaking of fast), which may unmask or worsen gastroparesis symptoms in individuals with diabetes. Symptoms such as early satiety, bloating, nausea, and glycemic fluctuations can further complicate diabetes management during fasting. This paper highlights the relationship... (More)
Gastroparesis, characterized by delayed gastric emptying without mechanical obstruction, is a recognized complication of long-standing diabetes. Its pathophysiology involves, amongst other mechanisms, autonomic dysfunction due to vagal nerve damage, impaired smooth muscle contractility, and hormonal dysregulation of intestinal motility. During Ramadan, fasting causes significant dietary changes due to prolonged fasting and the consumption of large meals for Iftar (breaking of fast), which may unmask or worsen gastroparesis symptoms in individuals with diabetes. Symptoms such as early satiety, bloating, nausea, and glycemic fluctuations can further complicate diabetes management during fasting. This paper highlights the relationship between Ramadan fasting and gastroparesis in individuals with diabetes, exploring underlying mechanisms, clinical manifestations, diagnostic approaches, and management strategies. A multidisciplinary approach involving dietary modifications, medication adjustments, lifestyle changes, and individualized medical counseling is essential for safe fasting, alongside the option to avoid fasting in individuals who are deemed too high at risk for fasting. Further research is needed to assess the prevalence of subclinical gastroparesis in fasting individuals with diabetes and to optimize risk stratification and management in these patients.
(Less)
- author
- Abdulrasak, Mohammed
LU
; Shaat, Nael
LU
; Someili, Ali M
and Mohrag, Mostafa
- organization
- publishing date
- 2025-03-15
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Clinical Medicine
- volume
- 14
- issue
- 6
- pages
- 1 - 12
- publisher
- MDPI AG
- external identifiers
-
- scopus:105001338128
- pmid:40142805
- ISSN
- 2077-0383
- DOI
- 10.3390/jcm14061997
- language
- English
- LU publication?
- yes
- id
- a74158d3-2c8e-41c0-a7f3-3a6fb0925aa9
- date added to LUP
- 2025-03-27 18:03:21
- date last changed
- 2025-06-30 10:25:19
@article{a74158d3-2c8e-41c0-a7f3-3a6fb0925aa9,
abstract = {{<p>Gastroparesis, characterized by delayed gastric emptying without mechanical obstruction, is a recognized complication of long-standing diabetes. Its pathophysiology involves, amongst other mechanisms, autonomic dysfunction due to vagal nerve damage, impaired smooth muscle contractility, and hormonal dysregulation of intestinal motility. During Ramadan, fasting causes significant dietary changes due to prolonged fasting and the consumption of large meals for Iftar (breaking of fast), which may unmask or worsen gastroparesis symptoms in individuals with diabetes. Symptoms such as early satiety, bloating, nausea, and glycemic fluctuations can further complicate diabetes management during fasting. This paper highlights the relationship between Ramadan fasting and gastroparesis in individuals with diabetes, exploring underlying mechanisms, clinical manifestations, diagnostic approaches, and management strategies. A multidisciplinary approach involving dietary modifications, medication adjustments, lifestyle changes, and individualized medical counseling is essential for safe fasting, alongside the option to avoid fasting in individuals who are deemed too high at risk for fasting. Further research is needed to assess the prevalence of subclinical gastroparesis in fasting individuals with diabetes and to optimize risk stratification and management in these patients.</p>}},
author = {{Abdulrasak, Mohammed and Shaat, Nael and Someili, Ali M and Mohrag, Mostafa}},
issn = {{2077-0383}},
language = {{eng}},
month = {{03}},
number = {{6}},
pages = {{1--12}},
publisher = {{MDPI AG}},
series = {{Journal of Clinical Medicine}},
title = {{Unmasking Gastroparesis in Diabetes During Ramadan : Challenges and Management Strategies}},
url = {{http://dx.doi.org/10.3390/jcm14061997}},
doi = {{10.3390/jcm14061997}},
volume = {{14}},
year = {{2025}},
}