Does Varicocele Repair Improve Conventional Semen Parameters? A Meta-Analytic Study of Before-After Data
Cannarella, R. ; Hazir, B. LU
and Agarwal, A.
(2024)
In World Journal of Men's Health
42(1).
p.92-132
- Abstract
- Purpose: The purpose of this meta-analysis is to study the impact of varicocele repair in the largest cohort of infertile males with clinical varicocele by including all available studies, with no language restrictions, comparing intra-person conventional semen parameters before and after the repair of varicoceles. Materials and Methods: The meta-analysis was performed according to PRISMA-P and MOOSE guidelines. A systematic search was performed in Scopus, PubMed, Cochrane, and Embase databases. Eligible studies were selected according to the PICOS model (Population: infertile male patients with clinical varicocele; Intervention: varicocele repair; Comparison: intra-person before-after varicocele repair; Outcome: conventional semen... (More)
- Purpose: The purpose of this meta-analysis is to study the impact of varicocele repair in the largest cohort of infertile males with clinical varicocele by including all available studies, with no language restrictions, comparing intra-person conventional semen parameters before and after the repair of varicoceles. Materials and Methods: The meta-analysis was performed according to PRISMA-P and MOOSE guidelines. A systematic search was performed in Scopus, PubMed, Cochrane, and Embase databases. Eligible studies were selected according to the PICOS model (Population: infertile male patients with clinical varicocele; Intervention: varicocele repair; Comparison: intra-person before-after varicocele repair; Outcome: conventional semen parameters; Study type: randomized controlled trials [RCTs], observational and case-control studies). Results: Out of 1,632 screened abstracts, 351 articles (23 RCTs, 292 observational, and 36 case-control studies) were included in the quantitative analysis. The before-and-after analysis showed significant improvements in all semen parameters after varicocele repair (except sperm vitality); semen volume: standardized mean difference (SMD) 0.203, 95% CI: 0.129–0.278; p (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/a748a143-e987-4ac2-bbf6-73f4786f2543
- author
- Cannarella, R.
; Hazir, B.
LU
and Agarwal, A.
- author collaboration
- organization
- publishing date
- 2024
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Controlled before-after studies, Infertility, male, Meta-analysis, Varicocele
- in
- World Journal of Men's Health
- volume
- 42
- issue
- 1
- pages
- 92 - 132
- publisher
- Korean Society for Sexual Medicine and Andrology
- external identifiers
-
- scopus:85175731583
- ISSN
- 2287-4208
- DOI
- 10.5534/wjmh.230034
- language
- English
- LU publication?
- yes
- id
- a748a143-e987-4ac2-bbf6-73f4786f2543
- date added to LUP
- 2024-01-16 13:52:33
- date last changed
- 2024-01-16 13:53:58
@article{a748a143-e987-4ac2-bbf6-73f4786f2543,
abstract = {{Purpose: The purpose of this meta-analysis is to study the impact of varicocele repair in the largest cohort of infertile males with clinical varicocele by including all available studies, with no language restrictions, comparing intra-person conventional semen parameters before and after the repair of varicoceles. Materials and Methods: The meta-analysis was performed according to PRISMA-P and MOOSE guidelines. A systematic search was performed in Scopus, PubMed, Cochrane, and Embase databases. Eligible studies were selected according to the PICOS model (Population: infertile male patients with clinical varicocele; Intervention: varicocele repair; Comparison: intra-person before-after varicocele repair; Outcome: conventional semen parameters; Study type: randomized controlled trials [RCTs], observational and case-control studies). Results: Out of 1,632 screened abstracts, 351 articles (23 RCTs, 292 observational, and 36 case-control studies) were included in the quantitative analysis. The before-and-after analysis showed significant improvements in all semen parameters after varicocele repair (except sperm vitality); semen volume: standardized mean difference (SMD) 0.203, 95% CI: 0.129–0.278; p}},
author = {{Cannarella, R. and Hazir, B. and Agarwal, A.}},
issn = {{2287-4208}},
keywords = {{Controlled before-after studies; Infertility, male; Meta-analysis; Varicocele}},
language = {{eng}},
number = {{1}},
pages = {{92--132}},
publisher = {{Korean Society for Sexual Medicine and Andrology}},
series = {{World Journal of Men's Health}},
title = {{Does Varicocele Repair Improve Conventional Semen Parameters? A Meta-Analytic Study of Before-After Data}},
url = {{http://dx.doi.org/10.5534/wjmh.230034}},
doi = {{10.5534/wjmh.230034}},
volume = {{42}},
year = {{2024}},
}