The Effect of Muscle Loading on Skeletal Muscle Regenerative Potential An Update of Current Research Findings Relating to Aging and Neuromuscular Pathology
(2009) In American Journal of Physical Medicine and Rehabilitation 88(2). p.145-155- Abstract
- Skeletal muscle is a dynamic tissue with a remarkable ability to continuously respond to environmental stimuli. Among its adaptive responses is the widely investigated ability of skeletal muscle to regenerate after loading or injury or both. Although significant basic science efforts have been dedicated to better understand the underlying mechanism controlling skeletal muscle regeneration, there has been relatively little impact in the clinical approaches used to treat skeletal muscle injuries and wasting. The purpose of this review article is to provide an overview of the basic biology of satellite cell function in response to muscle loading and to relate these findings in the context of aging and neuromuscular pathology for the... (More)
- Skeletal muscle is a dynamic tissue with a remarkable ability to continuously respond to environmental stimuli. Among its adaptive responses is the widely investigated ability of skeletal muscle to regenerate after loading or injury or both. Although significant basic science efforts have been dedicated to better understand the underlying mechanism controlling skeletal muscle regeneration, there has been relatively little impact in the clinical approaches used to treat skeletal muscle injuries and wasting. The purpose of this review article is to provide an overview of the basic biology of satellite cell function in response to muscle loading and to relate these findings in the context of aging and neuromuscular pathology for the rehabilitation medicine specialist. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1312358
- author
- Ambrosio, Fabrisia ; Kadi, Fawzi ; Lexell, Jan LU ; Fitzgerald, G. Kelley ; Boninger, Michael L. and Huard, Johnny
- organization
- publishing date
- 2009
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Exercise, Regeneration, Skeletal Muscle, Stem Cells, Satellite Cells
- in
- American Journal of Physical Medicine and Rehabilitation
- volume
- 88
- issue
- 2
- pages
- 145 - 155
- publisher
- Lippincott Williams & Wilkins
- external identifiers
-
- wos:000262739900009
- scopus:59649128291
- pmid:19169178
- ISSN
- 1537-7385
- DOI
- 10.1097/PHM.0b013e3181951fc5
- language
- English
- LU publication?
- yes
- id
- a7afa4dc-3415-4539-9574-76100ad14038 (old id 1312358)
- date added to LUP
- 2016-04-01 14:39:16
- date last changed
- 2022-03-14 06:59:39
@article{a7afa4dc-3415-4539-9574-76100ad14038,
abstract = {{Skeletal muscle is a dynamic tissue with a remarkable ability to continuously respond to environmental stimuli. Among its adaptive responses is the widely investigated ability of skeletal muscle to regenerate after loading or injury or both. Although significant basic science efforts have been dedicated to better understand the underlying mechanism controlling skeletal muscle regeneration, there has been relatively little impact in the clinical approaches used to treat skeletal muscle injuries and wasting. The purpose of this review article is to provide an overview of the basic biology of satellite cell function in response to muscle loading and to relate these findings in the context of aging and neuromuscular pathology for the rehabilitation medicine specialist.}},
author = {{Ambrosio, Fabrisia and Kadi, Fawzi and Lexell, Jan and Fitzgerald, G. Kelley and Boninger, Michael L. and Huard, Johnny}},
issn = {{1537-7385}},
keywords = {{Exercise; Regeneration; Skeletal Muscle; Stem Cells; Satellite Cells}},
language = {{eng}},
number = {{2}},
pages = {{145--155}},
publisher = {{Lippincott Williams & Wilkins}},
series = {{American Journal of Physical Medicine and Rehabilitation}},
title = {{The Effect of Muscle Loading on Skeletal Muscle Regenerative Potential An Update of Current Research Findings Relating to Aging and Neuromuscular Pathology}},
url = {{http://dx.doi.org/10.1097/PHM.0b013e3181951fc5}},
doi = {{10.1097/PHM.0b013e3181951fc5}},
volume = {{88}},
year = {{2009}},
}