Assessment of microvessel density in core needle biopsy specimen in breast cancer
Rydén, Lisa LU
; Boiesen, Poul
and Jonsson, Per-Ebbe
(2004)
In Anticancer research
24(1).
p.371-375
- Abstract
- AIM: Estimation of microvessel density (MVD) in primary breast cancer in core needle biopsies (CNB) may predict response to systemic therapy. The aim of the present study was to explore the accuracy of assessment of MVD in CNB related to MVD in excised tumours. MATERIAL AND METHODS: MVD was estimated in core biopsies and subsequently excised tumours in 54 consecutive patients with breast cancer without pre-operative treatment. RESULTS: The correlation between MVD in CNB and excised tumours was non-significant. However, in tumours larger than 20 mm (r=0.56, p=0.005) and in lobular carcinomas (r=0.55, p=0.014) a significant correlation was observed. CONCLUSION: The overall accuracy between estimation of MVD on CNB and excised breast tumours... (More)
- AIM: Estimation of microvessel density (MVD) in primary breast cancer in core needle biopsies (CNB) may predict response to systemic therapy. The aim of the present study was to explore the accuracy of assessment of MVD in CNB related to MVD in excised tumours. MATERIAL AND METHODS: MVD was estimated in core biopsies and subsequently excised tumours in 54 consecutive patients with breast cancer without pre-operative treatment. RESULTS: The correlation between MVD in CNB and excised tumours was non-significant. However, in tumours larger than 20 mm (r=0.56, p=0.005) and in lobular carcinomas (r=0.55, p=0.014) a significant correlation was observed. CONCLUSION: The overall accuracy between estimation of MVD on CNB and excised breast tumours was non-significant. The usefulness of MVD in CNB as a marker of response to systemic therapy should be further validated before it can be used in clinical practice. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1130432
- author
- Rydén, Lisa
LU
; Boiesen, Poul
and Jonsson, Per-Ebbe
- organization
- publishing date
- 2004
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Anticancer research
- volume
- 24
- issue
- 1
- pages
- 371 - 375
- publisher
- International Institute of Cancer Research
- external identifiers
-
- pmid:15015623
- scopus:1442350508
- ISSN
- 1791-7530
- language
- English
- LU publication?
- yes
- id
- a7f8a16c-d21a-4f36-98d1-2629a054f2a8 (old id 1130432)
- date added to LUP
- 2016-04-01 11:53:14
- date last changed
- 2022-01-26 19:42:45
@article{a7f8a16c-d21a-4f36-98d1-2629a054f2a8,
abstract = {{AIM: Estimation of microvessel density (MVD) in primary breast cancer in core needle biopsies (CNB) may predict response to systemic therapy. The aim of the present study was to explore the accuracy of assessment of MVD in CNB related to MVD in excised tumours. MATERIAL AND METHODS: MVD was estimated in core biopsies and subsequently excised tumours in 54 consecutive patients with breast cancer without pre-operative treatment. RESULTS: The correlation between MVD in CNB and excised tumours was non-significant. However, in tumours larger than 20 mm (r=0.56, p=0.005) and in lobular carcinomas (r=0.55, p=0.014) a significant correlation was observed. CONCLUSION: The overall accuracy between estimation of MVD on CNB and excised breast tumours was non-significant. The usefulness of MVD in CNB as a marker of response to systemic therapy should be further validated before it can be used in clinical practice.}},
author = {{Rydén, Lisa and Boiesen, Poul and Jonsson, Per-Ebbe}},
issn = {{1791-7530}},
language = {{eng}},
number = {{1}},
pages = {{371--375}},
publisher = {{International Institute of Cancer Research}},
series = {{Anticancer research}},
title = {{Assessment of microvessel density in core needle biopsy specimen in breast cancer}},
volume = {{24}},
year = {{2004}},
}