Vitamin K and its Role in Diabetic Vascular Complications and Low-Grade Inflammation
Dahlberg, Sofia and Schött, Ulf LU
(2018)
In Journal of Diabetes and Treatment
2018(1).
- Abstract
- This review summarizes the involvement of vitamin K and the extrahepatic Gla proteins matrix Gla protein (MGP), Os-teocalcin (OC) and growth arrest-specific gene 6 protein (Gas6) in the development and progression of diabetes: in particular, complications related to angiopathy and inflammation. High vitamin K intake has been associated with a decreased risk of type 2 diabetes. Furthermore, in type 2 diabetic patients, the extent of artery calcification correlates to levels of the uncarboxylated Gla protein MGP, and supplementation with vitamin K has been shown to reduce oxidative stress markers as well as metabolic risk markers for diabetes.
- Abstract (Swedish)
- This review summarizes the involvement of vitamin K and the extrahepatic Gla proteins matrix Gla protein (MGP), Os-teocalcin (OC) and growth arrest-specific gene 6 protein (Gas6) in the development and progression of diabetes: in particular, complications related to angiopathy and inflammation. High vitamin K intake has been associated with a decreased risk of type 2 diabetes. Furthermore, in type 2 diabetic patients, the extent of artery calcification correlates to levels of the uncarboxylated Gla protein MGP, and supplementation with vitamin K has been shown to reduce oxidative stress markers as well as metabolic risk markers for diabetes.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/a8076424-3979-4835-99aa-57940d27c2f8
- author
- Dahlberg, Sofia
and Schött, Ulf
LU
- organization
- publishing date
- 2018-01-24
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Diabetes and Treatment
- volume
- 2018
- issue
- 1
- article number
- JDBT-138
- pages
- 6 pages
- publisher
- Gavin Publishers
- ISSN
- 2574-7568
- DOI
- 10.29011/2574-7568.000038
- project
- Koagulation vid kirurgi och kritisk sjukdom
- language
- English
- LU publication?
- yes
- id
- a8076424-3979-4835-99aa-57940d27c2f8
- alternative location
- https://gavinpublishers.com/admin/assets/articles_pdf/1516797089article_pdf158589474.pdf
- date added to LUP
- 2018-02-02 16:10:24
- date last changed
- 2025-08-01 03:00:15
@article{a8076424-3979-4835-99aa-57940d27c2f8,
abstract = {{This review summarizes the involvement of vitamin K and the extrahepatic Gla proteins matrix Gla protein (MGP), Os-teocalcin (OC) and growth arrest-specific gene 6 protein (Gas6) in the development and progression of diabetes: in particular, complications related to angiopathy and inflammation. High vitamin K intake has been associated with a decreased risk of type 2 diabetes. Furthermore, in type 2 diabetic patients, the extent of artery calcification correlates to levels of the uncarboxylated Gla protein MGP, and supplementation with vitamin K has been shown to reduce oxidative stress markers as well as metabolic risk markers for diabetes.}},
author = {{Dahlberg, Sofia and Schött, Ulf}},
issn = {{2574-7568}},
language = {{eng}},
month = {{01}},
number = {{1}},
publisher = {{Gavin Publishers}},
series = {{Journal of Diabetes and Treatment}},
title = {{Vitamin K and its Role in Diabetic Vascular Complications and Low-Grade Inflammation}},
url = {{http://dx.doi.org/10.29011/2574-7568.000038}},
doi = {{10.29011/2574-7568.000038}},
volume = {{2018}},
year = {{2018}},
}