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Differentiation of diabetes by pathophysiology, natural history, and prognosis

Skyler, Jay S; Bakris, George L.; Bonifacio, Ezio; Darsow, Tamara; Eckel, Robert H.; Groop, Leif LU ; Groop, Per-Henrik; Handelsman, Yehuda; Insel, Richard A and Mathieu, Chantal, et al. (2017) In Diabetes 66(2). p.241-255
Abstract

The American Diabetes Association, JDRF, the European Association for the Study of Diabetes, and the American Association of Clinical Endocrinologists convened a research symposium, "The Differentiation of Diabetes by Pathophysiology, Natural History and Prognosis" on 10-12 October 2015. International experts in genetics, immunology, metabolism, endocrinology, and systems biology discussed genetic and environmental determinants of type 1 and type 2 diabetes risk and progression, as well as complications. The participants debated how to determine appropriate therapeutic approaches based on disease pathophysiology and stage and defined remaining research gaps hindering a personalized medical approach for diabetes to drive the field to... (More)

The American Diabetes Association, JDRF, the European Association for the Study of Diabetes, and the American Association of Clinical Endocrinologists convened a research symposium, "The Differentiation of Diabetes by Pathophysiology, Natural History and Prognosis" on 10-12 October 2015. International experts in genetics, immunology, metabolism, endocrinology, and systems biology discussed genetic and environmental determinants of type 1 and type 2 diabetes risk and progression, as well as complications. The participants debated how to determine appropriate therapeutic approaches based on disease pathophysiology and stage and defined remaining research gaps hindering a personalized medical approach for diabetes to drive the field to address these gaps. The authors recommend a structure for data stratification to define the phenotypes and genotypes of subtypes of diabetes that will facilitate individualized treatment.

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organization
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type
Contribution to journal
publication status
published
subject
in
Diabetes
volume
66
issue
2
pages
15 pages
publisher
American Diabetes Association Inc.
external identifiers
  • scopus:85011634413
  • wos:000392691000002
ISSN
0012-1797
DOI
10.2337/db16-0806
language
English
LU publication?
yes
id
a809d859-7baa-41e2-867c-6fc87044e1e3
date added to LUP
2017-02-20 11:01:10
date last changed
2018-11-18 04:51:56
@article{a809d859-7baa-41e2-867c-6fc87044e1e3,
  abstract     = {<p>The American Diabetes Association, JDRF, the European Association for the Study of Diabetes, and the American Association of Clinical Endocrinologists convened a research symposium, "The Differentiation of Diabetes by Pathophysiology, Natural History and Prognosis" on 10-12 October 2015. International experts in genetics, immunology, metabolism, endocrinology, and systems biology discussed genetic and environmental determinants of type 1 and type 2 diabetes risk and progression, as well as complications. The participants debated how to determine appropriate therapeutic approaches based on disease pathophysiology and stage and defined remaining research gaps hindering a personalized medical approach for diabetes to drive the field to address these gaps. The authors recommend a structure for data stratification to define the phenotypes and genotypes of subtypes of diabetes that will facilitate individualized treatment.</p>},
  author       = {Skyler, Jay S and Bakris, George L. and Bonifacio, Ezio and Darsow, Tamara and Eckel, Robert H. and Groop, Leif and Groop, Per-Henrik and Handelsman, Yehuda and Insel, Richard A and Mathieu, Chantal and McElvaine, Allison T. and Palmer, Jerry P. and Pugliese, Alberto and Schatz, Desmond A and Sosenko, Jay M and Wilding, John P H and Ratner, Robert E},
  issn         = {0012-1797},
  language     = {eng},
  month        = {02},
  number       = {2},
  pages        = {241--255},
  publisher    = {American Diabetes Association Inc.},
  series       = {Diabetes},
  title        = {Differentiation of diabetes by pathophysiology, natural history, and prognosis},
  url          = {http://dx.doi.org/10.2337/db16-0806},
  volume       = {66},
  year         = {2017},
}