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Cracking the Sugar Code by Mass Spectrometry : An Invited Perspective in Honor of Dr. Catherine E. Costello, Recipient of the 2017 ASMS Distinguished Contribution Award

Mirgorodskaya, Ekaterina ; Karlsson, Niclas G. ; Sihlbom, Carina ; Larson, Göran and Nilsson, Carol L. LU (2018) In Journal of the American Society for Mass Spectrometry 29(6). p.1065-1074
Abstract

The structural study of glycans and glycoconjugates is essential to assign their roles in homeostasis, health, and disease. Once dominated by nuclear magnetic resonance spectroscopy, mass spectrometric methods have become the preferred toolbox for the determination of glycan structures at high sensitivity. The patterns of such structures in different cellular states now allow us to interpret the sugar codes in health and disease, based on structure-function relationships. Dr. Catherine E. Costello was the 2017 recipient of the American Society for Mass Spectrometry’s Distinguished Contribution Award. In this Perspective article, we describe her seminal work in a historical and geographical context and review the impact of her research... (More)

The structural study of glycans and glycoconjugates is essential to assign their roles in homeostasis, health, and disease. Once dominated by nuclear magnetic resonance spectroscopy, mass spectrometric methods have become the preferred toolbox for the determination of glycan structures at high sensitivity. The patterns of such structures in different cellular states now allow us to interpret the sugar codes in health and disease, based on structure-function relationships. Dr. Catherine E. Costello was the 2017 recipient of the American Society for Mass Spectrometry’s Distinguished Contribution Award. In this Perspective article, we describe her seminal work in a historical and geographical context and review the impact of her research accomplishments in the field. 8[Figure not available: see fulltext.].

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Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Glycan mass spectrometry, History of mass spectrometry, Review, Structural mass spectrometry
in
Journal of the American Society for Mass Spectrometry
volume
29
issue
6
pages
10 pages
publisher
Elsevier
external identifiers
  • scopus:85048678709
  • pmid:29644549
ISSN
1044-0305
DOI
10.1007/s13361-018-1912-3
language
English
LU publication?
yes
id
a81e5117-4cb2-4930-8952-c4b8d45102ee
date added to LUP
2018-06-29 14:27:22
date last changed
2020-03-24 06:16:51
@article{a81e5117-4cb2-4930-8952-c4b8d45102ee,
  abstract     = {<p>The structural study of glycans and glycoconjugates is essential to assign their roles in homeostasis, health, and disease. Once dominated by nuclear magnetic resonance spectroscopy, mass spectrometric methods have become the preferred toolbox for the determination of glycan structures at high sensitivity. The patterns of such structures in different cellular states now allow us to interpret the sugar codes in health and disease, based on structure-function relationships. Dr. Catherine E. Costello was the 2017 recipient of the American Society for Mass Spectrometry’s Distinguished Contribution Award. In this Perspective article, we describe her seminal work in a historical and geographical context and review the impact of her research accomplishments in the field. 8[Figure not available: see fulltext.].</p>},
  author       = {Mirgorodskaya, Ekaterina and Karlsson, Niclas G. and Sihlbom, Carina and Larson, Göran and Nilsson, Carol L.},
  issn         = {1044-0305},
  language     = {eng},
  month        = {06},
  number       = {6},
  pages        = {1065--1074},
  publisher    = {Elsevier},
  series       = {Journal of the American Society for Mass Spectrometry},
  title        = {Cracking the Sugar Code by Mass Spectrometry : An Invited Perspective in Honor of Dr. Catherine E. Costello, Recipient of the 2017 ASMS Distinguished Contribution Award},
  url          = {http://dx.doi.org/10.1007/s13361-018-1912-3},
  doi          = {10.1007/s13361-018-1912-3},
  volume       = {29},
  year         = {2018},
}