Quantitative evaluation of a single-distance phase-retrieval method applied on in-line phase-contrast images of a mouse lung
Mohammadi, Sara ; Larsson, Emanuel LU
; Alves, Frauke
; Dal Monego, Simeone
; Biffi, Stefania
; Garrovo, Chiara
; Lorenzon, Andrea
; Tromba, Giuliana
and Dullin, Christian
(2014)
In Journal of Synchrotron Radiation
21(4).
p.784-789
- Abstract
Propagation-based X-ray phase-contrast computed tomography (PBI) has already proven its potential in a great variety of soft-tissue-related applications including lung imaging. However, the strong edge enhancement, caused by the phase effects, often hampers image segmentation and therefore the quantitative analysis of data sets. Here, the benefits of applying single-distance phase retrieval prior to the three-dimensional reconstruction (PhR) are discussed and quantified compared with three-dimensional reconstructions of conventional PBI data sets in terms of contrast-to-noise ratio (CNR) and preservation of image features. The PhR data sets show more than a tenfold higher CNR and only minor blurring of the edges when compared with PBI... (More)
Propagation-based X-ray phase-contrast computed tomography (PBI) has already proven its potential in a great variety of soft-tissue-related applications including lung imaging. However, the strong edge enhancement, caused by the phase effects, often hampers image segmentation and therefore the quantitative analysis of data sets. Here, the benefits of applying single-distance phase retrieval prior to the three-dimensional reconstruction (PhR) are discussed and quantified compared with three-dimensional reconstructions of conventional PBI data sets in terms of contrast-to-noise ratio (CNR) and preservation of image features. The PhR data sets show more than a tenfold higher CNR and only minor blurring of the edges when compared with PBI in a predominately absorption-based set-up. Accordingly, phase retrieval increases the sensitivity and provides more functionality in computed tomography imaging.
(Less)
- author
- Mohammadi, Sara
; Larsson, Emanuel
LU
; Alves, Frauke
; Dal Monego, Simeone
; Biffi, Stefania
; Garrovo, Chiara
; Lorenzon, Andrea
; Tromba, Giuliana
and Dullin, Christian
- publishing date
- 2014-07
- type
- Contribution to journal
- publication status
- published
- keywords
- computed tomography, lung imaging, phase retrieval, phase-contrast imaging
- in
- Journal of Synchrotron Radiation
- volume
- 21
- issue
- 4
- pages
- 784 - 789
- publisher
- International Union of Crystallography
- external identifiers
-
- scopus:84903604376
- pmid:24971975
- ISSN
- 0909-0495
- DOI
- 10.1107/S1600577514009333
- language
- English
- LU publication?
- no
- id
- a8522440-94e0-4995-8377-a45fd400ce82
- date added to LUP
- 2025-08-26 11:29:54
- date last changed
- 2025-08-27 03:24:52
@article{a8522440-94e0-4995-8377-a45fd400ce82,
abstract = {{<p>Propagation-based X-ray phase-contrast computed tomography (PBI) has already proven its potential in a great variety of soft-tissue-related applications including lung imaging. However, the strong edge enhancement, caused by the phase effects, often hampers image segmentation and therefore the quantitative analysis of data sets. Here, the benefits of applying single-distance phase retrieval prior to the three-dimensional reconstruction (PhR) are discussed and quantified compared with three-dimensional reconstructions of conventional PBI data sets in terms of contrast-to-noise ratio (CNR) and preservation of image features. The PhR data sets show more than a tenfold higher CNR and only minor blurring of the edges when compared with PBI in a predominately absorption-based set-up. Accordingly, phase retrieval increases the sensitivity and provides more functionality in computed tomography imaging.</p>}},
author = {{Mohammadi, Sara and Larsson, Emanuel and Alves, Frauke and Dal Monego, Simeone and Biffi, Stefania and Garrovo, Chiara and Lorenzon, Andrea and Tromba, Giuliana and Dullin, Christian}},
issn = {{0909-0495}},
keywords = {{computed tomography; lung imaging; phase retrieval; phase-contrast imaging}},
language = {{eng}},
number = {{4}},
pages = {{784--789}},
publisher = {{International Union of Crystallography}},
series = {{Journal of Synchrotron Radiation}},
title = {{Quantitative evaluation of a single-distance phase-retrieval method applied on in-line phase-contrast images of a mouse lung}},
url = {{http://dx.doi.org/10.1107/S1600577514009333}},
doi = {{10.1107/S1600577514009333}},
volume = {{21}},
year = {{2014}},
}