Assignment of gene for coagulation factor V to chromosome 1 in man and to chromosome 13 in rat
(1988) In Somatic Cell and Molecular Genetics 14(5). p.14-509- Abstract
- Two different factor V cDNA fragments were used as hydridization probes in the chromosomal assignment of the human and rat factor V genes. A 1.6-kb EcoRI fragment was used as a hybridization probe to analyze a panel of human-rodent somatic cell hybrids. Cosegregation of factor V specific DNA restriction fragments with human chromosome 1 was observed. In addition, a panel of rat-mouse somatic cell hybrids was analyzed with another human factor V cDNA probe to localize the gene for rat coagulation factor V. In the rat, the gene for coagulation factor V was found to be located in chromosome 13. This is the first gene in the rat to be localized to chromosome 13.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3965159
- author
- Dahlbäck, Björn LU ; Hansson, C. ; Islam, M. Q. ; Szpirer, J. ; Szpirer, C. ; Lundwall, Åke LU and Levan, G.
- organization
- publishing date
- 1988
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- DNA Probes, Molecular, Cloning, Pair 1, Human, *Chromosomes, *Chromosome Mapping, Animals, Southern, Blotting, Factor V/*genetics, Humans, Hybrid Cells, Nucleic Acid Hybridization, Rats, Research Support, Non-U.S. Gov't
- in
- Somatic Cell and Molecular Genetics
- volume
- 14
- issue
- 5
- pages
- 14 - 509
- publisher
- Springer
- external identifiers
-
- scopus:0023764379
- ISSN
- 0740-7750
- language
- English
- LU publication?
- yes
- additional info
- 5
- id
- a85d319f-ea9b-4f6f-94c3-fd85955e2c2a (old id 3965159)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3175767
- date added to LUP
- 2016-04-04 13:44:14
- date last changed
- 2022-08-29 11:43:48
@article{a85d319f-ea9b-4f6f-94c3-fd85955e2c2a, abstract = {{Two different factor V cDNA fragments were used as hydridization probes in the chromosomal assignment of the human and rat factor V genes. A 1.6-kb EcoRI fragment was used as a hybridization probe to analyze a panel of human-rodent somatic cell hybrids. Cosegregation of factor V specific DNA restriction fragments with human chromosome 1 was observed. In addition, a panel of rat-mouse somatic cell hybrids was analyzed with another human factor V cDNA probe to localize the gene for rat coagulation factor V. In the rat, the gene for coagulation factor V was found to be located in chromosome 13. This is the first gene in the rat to be localized to chromosome 13.}}, author = {{Dahlbäck, Björn and Hansson, C. and Islam, M. Q. and Szpirer, J. and Szpirer, C. and Lundwall, Åke and Levan, G.}}, issn = {{0740-7750}}, keywords = {{DNA Probes; Molecular; Cloning; Pair 1; Human; *Chromosomes; *Chromosome Mapping; Animals; Southern; Blotting; Factor V/*genetics; Humans; Hybrid Cells; Nucleic Acid Hybridization; Rats; Research Support; Non-U.S. Gov't}}, language = {{eng}}, number = {{5}}, pages = {{14--509}}, publisher = {{Springer}}, series = {{Somatic Cell and Molecular Genetics}}, title = {{Assignment of gene for coagulation factor V to chromosome 1 in man and to chromosome 13 in rat}}, url = {{http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3175767}}, volume = {{14}}, year = {{1988}}, }