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Differential molecular and behavioural response to L-DOPA in mice injected with 6-hydroxydopamine in the striatum or in the medial forebrain bundle

Francardo, Veronica LU ; Recchia, Alessandra LU ; Mohammed, Mohsin LU ; Nissbrandt, Hans and Cenci Nilsson, Angela LU orcid (2010)
Abstract
Unilateral lesions of nigrostriatal dopamine ( DA) pathways with 6-hydroxydopamine (6-OHDA) can be used to obtain a model of Parkinson's disease in the mouse. In the present study we examine two types of unilateral 6-OHDA lesions in the mouse for their ability to induce stable motor deficits and supersensitive molecular and behavioural response to L-DOPA.
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author
; ; ; and
organization
publishing date
type
Contribution to conference
publication status
published
subject
keywords
L-DOPA, 6-OHDA, mice
language
English
LU publication?
yes
id
a892222d-82eb-41d3-bd89-4dd1ceb5540f
date added to LUP
2016-06-02 10:38:19
date last changed
2018-11-21 21:24:06
@misc{a892222d-82eb-41d3-bd89-4dd1ceb5540f,
  abstract     = {{Unilateral lesions of nigrostriatal dopamine  ( DA) pathways with 6-hydroxydopamine (6-OHDA)  can be used to obtain a model of Parkinson's disease in the mouse. In the present study we examine two types of unilateral 6-OHDA lesions in the mouse for their ability to induce stable motor deficits and supersensitive molecular and behavioural response to L-DOPA.}},
  author       = {{Francardo, Veronica and Recchia, Alessandra and Mohammed, Mohsin and Nissbrandt, Hans and Cenci Nilsson, Angela}},
  keywords     = {{L-DOPA; 6-OHDA; mice}},
  language     = {{eng}},
  title        = {{Differential molecular and behavioural response to L-DOPA in mice injected with 6-hydroxydopamine in the striatum or in the medial forebrain bundle}},
  url          = {{https://lup.lub.lu.se/search/files/8117389/Poster.pdf}},
  year         = {{2010}},
}