The European Society for Blood and Marrow Transplantation (EBMT) roadmap and perspectives to improve nutritional care in patients undergoing hematopoietic stem cell transplantation on behalf of the Cellular Therapy and Immunobiology Working Party (CTIWP) and the Nurses Group (NG) of the EBMT
(2023) In Bone Marrow Transplantation 58(9). p.965-972- Abstract
Malnutrition is the most common comorbidity during the continuum of hematopoietic stem cell transplant (HSCT) and negatively impacts clinical outcomes, response to therapy, quality of life, and costs. The intensive conditioning regimen administered before transplant causes inflammatory damages to the gastrointestinal system, which themselves contribute to trigger graft versus host disease (GvHD) in the allogeneic setting. GvHD and other post-transplant complications such as infections adversely affect food intake and gut absorption of nutrients. Consequently, patients exhibit signs of malnutrition such as weight loss and muscle wasting, thus triggering a “vicious circle” that favours additional complications. Among HSCT centres, there... (More)
Malnutrition is the most common comorbidity during the continuum of hematopoietic stem cell transplant (HSCT) and negatively impacts clinical outcomes, response to therapy, quality of life, and costs. The intensive conditioning regimen administered before transplant causes inflammatory damages to the gastrointestinal system, which themselves contribute to trigger graft versus host disease (GvHD) in the allogeneic setting. GvHD and other post-transplant complications such as infections adversely affect food intake and gut absorption of nutrients. Consequently, patients exhibit signs of malnutrition such as weight loss and muscle wasting, thus triggering a “vicious circle” that favours additional complications. Among HSCT centres, there is marked variability in nutritional care, from screening for malnutrition to nutritional intervention. The present paper, elaborated by the Cellular Therapy and Immunobiology Working Party and the Nurses Group of the European Society for Blood and Marrow Transplantation, aims at defining a roadmap that identifies the main nutritional critical issues in the field of HSCT. This document will be propaedeutic to the development of clinical algorithms to counteract risk factors of malnutrition, based on scientific evidence and shared among HSCT centres, and thus maximize transplant outcomes.
(Less)
- author
- author collaboration
- organization
- publishing date
- 2023-09
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Bone Marrow Transplantation
- volume
- 58
- issue
- 9
- pages
- 8 pages
- publisher
- Nature Publishing Group
- external identifiers
-
- pmid:37407728
- scopus:85164481464
- ISSN
- 0268-3369
- DOI
- 10.1038/s41409-023-02018-z
- language
- English
- LU publication?
- yes
- id
- a8df3291-78f0-48ed-bbfb-f494824df310
- date added to LUP
- 2023-10-06 15:47:57
- date last changed
- 2024-04-19 02:03:23
@article{a8df3291-78f0-48ed-bbfb-f494824df310, abstract = {{<p>Malnutrition is the most common comorbidity during the continuum of hematopoietic stem cell transplant (HSCT) and negatively impacts clinical outcomes, response to therapy, quality of life, and costs. The intensive conditioning regimen administered before transplant causes inflammatory damages to the gastrointestinal system, which themselves contribute to trigger graft versus host disease (GvHD) in the allogeneic setting. GvHD and other post-transplant complications such as infections adversely affect food intake and gut absorption of nutrients. Consequently, patients exhibit signs of malnutrition such as weight loss and muscle wasting, thus triggering a “vicious circle” that favours additional complications. Among HSCT centres, there is marked variability in nutritional care, from screening for malnutrition to nutritional intervention. The present paper, elaborated by the Cellular Therapy and Immunobiology Working Party and the Nurses Group of the European Society for Blood and Marrow Transplantation, aims at defining a roadmap that identifies the main nutritional critical issues in the field of HSCT. This document will be propaedeutic to the development of clinical algorithms to counteract risk factors of malnutrition, based on scientific evidence and shared among HSCT centres, and thus maximize transplant outcomes.</p>}}, author = {{Casirati, Amanda and Salcedo, Isabel and Cereda, Emanuele and Chabannon, Christian and Ruggeri, Annalisa and Kuball, Jurgen and Clout, Ruth and Mooyaart, Jarl E. and Kenyon, Michelle and Caccialanza, Riccardo and Pedrazzoli, Paolo and Kisch, Annika M.}}, issn = {{0268-3369}}, language = {{eng}}, number = {{9}}, pages = {{965--972}}, publisher = {{Nature Publishing Group}}, series = {{Bone Marrow Transplantation}}, title = {{The European Society for Blood and Marrow Transplantation (EBMT) roadmap and perspectives to improve nutritional care in patients undergoing hematopoietic stem cell transplantation on behalf of the Cellular Therapy and Immunobiology Working Party (CTIWP) and the Nurses Group (NG) of the EBMT}}, url = {{http://dx.doi.org/10.1038/s41409-023-02018-z}}, doi = {{10.1038/s41409-023-02018-z}}, volume = {{58}}, year = {{2023}}, }