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The European Society for Blood and Marrow Transplantation (EBMT) roadmap and perspectives to improve nutritional care in patients undergoing hematopoietic stem cell transplantation on behalf of the Cellular Therapy and Immunobiology Working Party (CTIWP) and the Nurses Group (NG) of the EBMT

Casirati, Amanda ; Salcedo, Isabel ; Cereda, Emanuele ; Chabannon, Christian ; Ruggeri, Annalisa ; Kuball, Jurgen ; Clout, Ruth ; Mooyaart, Jarl E. ; Kenyon, Michelle and Caccialanza, Riccardo , et al. (2023) In Bone Marrow Transplantation 58(9). p.965-972
Abstract

Malnutrition is the most common comorbidity during the continuum of hematopoietic stem cell transplant (HSCT) and negatively impacts clinical outcomes, response to therapy, quality of life, and costs. The intensive conditioning regimen administered before transplant causes inflammatory damages to the gastrointestinal system, which themselves contribute to trigger graft versus host disease (GvHD) in the allogeneic setting. GvHD and other post-transplant complications such as infections adversely affect food intake and gut absorption of nutrients. Consequently, patients exhibit signs of malnutrition such as weight loss and muscle wasting, thus triggering a “vicious circle” that favours additional complications. Among HSCT centres, there... (More)

Malnutrition is the most common comorbidity during the continuum of hematopoietic stem cell transplant (HSCT) and negatively impacts clinical outcomes, response to therapy, quality of life, and costs. The intensive conditioning regimen administered before transplant causes inflammatory damages to the gastrointestinal system, which themselves contribute to trigger graft versus host disease (GvHD) in the allogeneic setting. GvHD and other post-transplant complications such as infections adversely affect food intake and gut absorption of nutrients. Consequently, patients exhibit signs of malnutrition such as weight loss and muscle wasting, thus triggering a “vicious circle” that favours additional complications. Among HSCT centres, there is marked variability in nutritional care, from screening for malnutrition to nutritional intervention. The present paper, elaborated by the Cellular Therapy and Immunobiology Working Party and the Nurses Group of the European Society for Blood and Marrow Transplantation, aims at defining a roadmap that identifies the main nutritional critical issues in the field of HSCT. This document will be propaedeutic to the development of clinical algorithms to counteract risk factors of malnutrition, based on scientific evidence and shared among HSCT centres, and thus maximize transplant outcomes.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Bone Marrow Transplantation
volume
58
issue
9
pages
8 pages
publisher
Nature Publishing Group
external identifiers
  • pmid:37407728
  • scopus:85164481464
ISSN
0268-3369
DOI
10.1038/s41409-023-02018-z
language
English
LU publication?
yes
id
a8df3291-78f0-48ed-bbfb-f494824df310
date added to LUP
2023-10-06 15:47:57
date last changed
2024-04-19 02:03:23
@article{a8df3291-78f0-48ed-bbfb-f494824df310,
  abstract     = {{<p>Malnutrition is the most common comorbidity during the continuum of hematopoietic stem cell transplant (HSCT) and negatively impacts clinical outcomes, response to therapy, quality of life, and costs. The intensive conditioning regimen administered before transplant causes inflammatory damages to the gastrointestinal system, which themselves contribute to trigger graft versus host disease (GvHD) in the allogeneic setting. GvHD and other post-transplant complications such as infections adversely affect food intake and gut absorption of nutrients. Consequently, patients exhibit signs of malnutrition such as weight loss and muscle wasting, thus triggering a “vicious circle” that favours additional complications. Among HSCT centres, there is marked variability in nutritional care, from screening for malnutrition to nutritional intervention. The present paper, elaborated by the Cellular Therapy and Immunobiology Working Party and the Nurses Group of the European Society for Blood and Marrow Transplantation, aims at defining a roadmap that identifies the main nutritional critical issues in the field of HSCT. This document will be propaedeutic to the development of clinical algorithms to counteract risk factors of malnutrition, based on scientific evidence and shared among HSCT centres, and thus maximize transplant outcomes.</p>}},
  author       = {{Casirati, Amanda and Salcedo, Isabel and Cereda, Emanuele and Chabannon, Christian and Ruggeri, Annalisa and Kuball, Jurgen and Clout, Ruth and Mooyaart, Jarl E. and Kenyon, Michelle and Caccialanza, Riccardo and Pedrazzoli, Paolo and Kisch, Annika M.}},
  issn         = {{0268-3369}},
  language     = {{eng}},
  number       = {{9}},
  pages        = {{965--972}},
  publisher    = {{Nature Publishing Group}},
  series       = {{Bone Marrow Transplantation}},
  title        = {{The European Society for Blood and Marrow Transplantation (EBMT) roadmap and perspectives to improve nutritional care in patients undergoing hematopoietic stem cell transplantation on behalf of the Cellular Therapy and Immunobiology Working Party (CTIWP) and the Nurses Group (NG) of the EBMT}},
  url          = {{http://dx.doi.org/10.1038/s41409-023-02018-z}},
  doi          = {{10.1038/s41409-023-02018-z}},
  volume       = {{58}},
  year         = {{2023}},
}