Metal chelator decreases alzheimer β-amyloid plaques
(2001) In Neuron 30(3). p.641-642- Abstract
Transgenic mice developing β-amyloid (Aβ) plaques are advancing experimental treatment strategies for Alzheimer's disease. The metal chelator, clioquinol, is reported by Cherny et al. (2001) to reduce Aβ plaques, presumably by chelation of Aβ-associated zinc and copper. This and other recent Aβ-modulating treatment approaches are discussed.
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https://lup.lub.lu.se/record/a8f03351-0b8d-42ac-9942-c471f63de1d8
- author
- Gouras, Gunnar K. LU and Beal, M. Flint
- publishing date
- 2001-05
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Neuron
- volume
- 30
- issue
- 3
- pages
- 641 - 642
- publisher
- Cell Press
- external identifiers
-
- pmid:11430794
- scopus:0034968120
- ISSN
- 0896-6273
- DOI
- 10.1016/S0896-6273(01)00330-0
- language
- English
- LU publication?
- no
- id
- a8f03351-0b8d-42ac-9942-c471f63de1d8
- date added to LUP
- 2020-02-20 14:45:18
- date last changed
- 2024-01-02 06:12:09
@article{a8f03351-0b8d-42ac-9942-c471f63de1d8, abstract = {{<p>Transgenic mice developing β-amyloid (Aβ) plaques are advancing experimental treatment strategies for Alzheimer's disease. The metal chelator, clioquinol, is reported by Cherny et al. (2001) to reduce Aβ plaques, presumably by chelation of Aβ-associated zinc and copper. This and other recent Aβ-modulating treatment approaches are discussed.</p>}}, author = {{Gouras, Gunnar K. and Beal, M. Flint}}, issn = {{0896-6273}}, language = {{eng}}, number = {{3}}, pages = {{641--642}}, publisher = {{Cell Press}}, series = {{Neuron}}, title = {{Metal chelator decreases alzheimer β-amyloid plaques}}, url = {{http://dx.doi.org/10.1016/S0896-6273(01)00330-0}}, doi = {{10.1016/S0896-6273(01)00330-0}}, volume = {{30}}, year = {{2001}}, }