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Metal chelator decreases alzheimer β-amyloid plaques

Gouras, Gunnar K. LU orcid and Beal, M. Flint (2001) In Neuron 30(3). p.641-642
Abstract

Transgenic mice developing β-amyloid (Aβ) plaques are advancing experimental treatment strategies for Alzheimer's disease. The metal chelator, clioquinol, is reported by Cherny et al. (2001) to reduce Aβ plaques, presumably by chelation of Aβ-associated zinc and copper. This and other recent Aβ-modulating treatment approaches are discussed.

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author
and
publishing date
type
Contribution to journal
publication status
published
subject
in
Neuron
volume
30
issue
3
pages
641 - 642
publisher
Cell Press
external identifiers
  • pmid:11430794
  • scopus:0034968120
ISSN
0896-6273
DOI
10.1016/S0896-6273(01)00330-0
language
English
LU publication?
no
id
a8f03351-0b8d-42ac-9942-c471f63de1d8
date added to LUP
2020-02-20 14:45:18
date last changed
2024-01-02 06:12:09
@article{a8f03351-0b8d-42ac-9942-c471f63de1d8,
  abstract     = {{<p>Transgenic mice developing β-amyloid (Aβ) plaques are advancing experimental treatment strategies for Alzheimer's disease. The metal chelator, clioquinol, is reported by Cherny et al. (2001) to reduce Aβ plaques, presumably by chelation of Aβ-associated zinc and copper. This and other recent Aβ-modulating treatment approaches are discussed.</p>}},
  author       = {{Gouras, Gunnar K. and Beal, M. Flint}},
  issn         = {{0896-6273}},
  language     = {{eng}},
  number       = {{3}},
  pages        = {{641--642}},
  publisher    = {{Cell Press}},
  series       = {{Neuron}},
  title        = {{Metal chelator decreases alzheimer β-amyloid plaques}},
  url          = {{http://dx.doi.org/10.1016/S0896-6273(01)00330-0}},
  doi          = {{10.1016/S0896-6273(01)00330-0}},
  volume       = {{30}},
  year         = {{2001}},
}