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Male-female differences in upregulation of vasoconstrictor responses in human cerebral arteries.

Ahnstedt, Hilda LU ; Cao, Lei LU ; Krause, Diana N ; Warfvinge, Karin LU ; Säveland, Hans LU ; Nilsson, Ola LU and Edvinsson, Lars LU (2013) In PLoS ONE 8(4).
Abstract
Male-female differences may significantly impact stroke prevention and treatment in men and women, however underlying mechanisms for sexual dimorphism in stroke are not understood. We previously found in males that cerebral ischemia upregulates contractile receptors in cerebral arteries, which is associated with lower blood flow. The present study investigates if cerebral arteries from men and women differ in cerebrovascular receptor upregulation.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
PLoS ONE
volume
8
issue
4
article number
e62698
publisher
Public Library of Science
external identifiers
  • wos:000321662800056
  • pmid:23658641
  • scopus:84876914743
  • pmid:23658641
ISSN
1932-6203
DOI
10.1371/journal.pone.0062698
language
English
LU publication?
yes
id
ab0ae69a-b743-4acb-9bf5-ea521dc6cf65 (old id 3804707)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/23658641?dopt=Abstract
date added to LUP
2016-04-01 14:33:44
date last changed
2020-01-12 16:23:51
@article{ab0ae69a-b743-4acb-9bf5-ea521dc6cf65,
  abstract     = {Male-female differences may significantly impact stroke prevention and treatment in men and women, however underlying mechanisms for sexual dimorphism in stroke are not understood. We previously found in males that cerebral ischemia upregulates contractile receptors in cerebral arteries, which is associated with lower blood flow. The present study investigates if cerebral arteries from men and women differ in cerebrovascular receptor upregulation.},
  author       = {Ahnstedt, Hilda and Cao, Lei and Krause, Diana N and Warfvinge, Karin and Säveland, Hans and Nilsson, Ola and Edvinsson, Lars},
  issn         = {1932-6203},
  language     = {eng},
  number       = {4},
  publisher    = {Public Library of Science},
  series       = {PLoS ONE},
  title        = {Male-female differences in upregulation of vasoconstrictor responses in human cerebral arteries.},
  url          = {https://lup.lub.lu.se/search/ws/files/4037952/4075196.pdf},
  doi          = {10.1371/journal.pone.0062698},
  volume       = {8},
  year         = {2013},
}