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Allergic contact dermatitis from octylisothiazolinone

Mose, Anja P. LU ; Frost, Simon ; Öhlund, Ulf and Andersen, Klaus E. (2013) In Contact Dermatitis 69(1). p.49-52
Abstract

BACKGROUND: Octylisothiazolinone is a biocide that has been reported as a moderate, but rare contact allergen.

OBJECTIVES: To investigate the occurrence of octylisothiazolinone contact allergy and allergic contact dermatitis diagnosed and registered in the Allergen Bank at Odense University Hospital during the past 20 years. Octylisothiazolinone has been used for targeted testing only.

METHOD: All octylisothiazolinone-patch test results registered in the Allergen Bank between January 1992 and February 2012 were analyzed.

RESULTS: A total of 20 out of 648 patients patch tested with octylisothiazolinone had positive reactions. The majority of the patients (90%) with relevant sensitizations to octylisothiazolinone had... (More)

BACKGROUND: Octylisothiazolinone is a biocide that has been reported as a moderate, but rare contact allergen.

OBJECTIVES: To investigate the occurrence of octylisothiazolinone contact allergy and allergic contact dermatitis diagnosed and registered in the Allergen Bank at Odense University Hospital during the past 20 years. Octylisothiazolinone has been used for targeted testing only.

METHOD: All octylisothiazolinone-patch test results registered in the Allergen Bank between January 1992 and February 2012 were analyzed.

RESULTS: A total of 20 out of 648 patients patch tested with octylisothiazolinone had positive reactions. The majority of the patients (90%) with relevant sensitizations to octylisothiazolinone had been exposed in occupational settings and most patients were painters.

CONCLUSIONS: Octylisothiazolinone is a relevant sensitizer.

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author
; ; and
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Adult, Causality, Denmark/epidemiology, Dermatitis, Allergic Contact/diagnosis, Dermatitis, Occupational/diagnosis, Female, Humans, Male, Middle Aged, Occupational Exposure/adverse effects, Paint/adverse effects, Patch Tests/statistics & numerical data, Risk Factors, Thiazoles/administration & dosage, Workplace, Young Adult
in
Contact Dermatitis
volume
69
issue
1
pages
4 pages
publisher
Wiley-Blackwell
external identifiers
  • scopus:84879390871
  • pmid:23782358
  • pmid:23782358
ISSN
0105-1873
DOI
10.1111/cod.12068
language
English
LU publication?
no
id
aba9d423-119b-4c4f-9b99-1ae64ac31d43
date added to LUP
2023-09-22 12:21:54
date last changed
2024-04-19 02:33:32
@article{aba9d423-119b-4c4f-9b99-1ae64ac31d43,
  abstract     = {{<p>BACKGROUND: Octylisothiazolinone is a biocide that has been reported as a moderate, but rare contact allergen.</p><p>OBJECTIVES: To investigate the occurrence of octylisothiazolinone contact allergy and allergic contact dermatitis diagnosed and registered in the Allergen Bank at Odense University Hospital during the past 20 years. Octylisothiazolinone has been used for targeted testing only.</p><p>METHOD: All octylisothiazolinone-patch test results registered in the Allergen Bank between January 1992 and February 2012 were analyzed.</p><p>RESULTS: A total of 20 out of 648 patients patch tested with octylisothiazolinone had positive reactions. The majority of the patients (90%) with relevant sensitizations to octylisothiazolinone had been exposed in occupational settings and most patients were painters.</p><p>CONCLUSIONS: Octylisothiazolinone is a relevant sensitizer.</p>}},
  author       = {{Mose, Anja P. and Frost, Simon and Öhlund, Ulf and Andersen, Klaus E.}},
  issn         = {{0105-1873}},
  keywords     = {{Adult; Causality; Denmark/epidemiology; Dermatitis, Allergic Contact/diagnosis; Dermatitis, Occupational/diagnosis; Female; Humans; Male; Middle Aged; Occupational Exposure/adverse effects; Paint/adverse effects; Patch Tests/statistics & numerical data; Risk Factors; Thiazoles/administration & dosage; Workplace; Young Adult}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{49--52}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Contact Dermatitis}},
  title        = {{Allergic contact dermatitis from octylisothiazolinone}},
  url          = {{http://dx.doi.org/10.1111/cod.12068}},
  doi          = {{10.1111/cod.12068}},
  volume       = {{69}},
  year         = {{2013}},
}