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Artificial carrier for oxygen supply in biological systems

Dey, Estera LU ; Norrlow, O and Liu, Yang LU (2004) In Applied Microbiology and Biotechnology 64(2). p.187-191
Abstract
Several poly (dimethylsiloxanes) (PDMS) copolymers of dimethylsiloxane (DMS) with ethylene or propylene oxide were tested as artificial carriers for the delivery of oxygen to biological systems. Copolymers with a DMS content of 33% or lower enhanced glucose oxidation by 200% in contrast to the 25% increase produced by the same concentration of perfluorodecalin. When 0.05% of the copolymer with 18% DMS was included in the growth media of Bacillus thuriginensis, the biomass (growth rate) increased 1.5-fold. With 0.1% of this copolymer, actinorhodin production by Streptomyces coelicolor A3 (2) occurred in half the normal time and with an increased yield. In conclusion, these PDMS copolymers are a good alternative to perfluorodecalin as oxygen... (More)
Several poly (dimethylsiloxanes) (PDMS) copolymers of dimethylsiloxane (DMS) with ethylene or propylene oxide were tested as artificial carriers for the delivery of oxygen to biological systems. Copolymers with a DMS content of 33% or lower enhanced glucose oxidation by 200% in contrast to the 25% increase produced by the same concentration of perfluorodecalin. When 0.05% of the copolymer with 18% DMS was included in the growth media of Bacillus thuriginensis, the biomass (growth rate) increased 1.5-fold. With 0.1% of this copolymer, actinorhodin production by Streptomyces coelicolor A3 (2) occurred in half the normal time and with an increased yield. In conclusion, these PDMS copolymers are a good alternative to perfluorodecalin as oxygen carriers in biotechnological processes. (Less)
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author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Applied Microbiology and Biotechnology
volume
64
issue
2
pages
187 - 191
publisher
Springer
external identifiers
  • wos:000220565100005
  • pmid:14593505
  • scopus:2142761526
  • pmid:14593505
ISSN
1432-0614
DOI
10.1007/s00253-003-1454-9
language
English
LU publication?
yes
id
abc0576f-a9e4-4968-84fc-273d0bf2e265 (old id 141051)
date added to LUP
2016-04-01 15:19:33
date last changed
2022-01-28 04:48:41
@article{abc0576f-a9e4-4968-84fc-273d0bf2e265,
  abstract     = {{Several poly (dimethylsiloxanes) (PDMS) copolymers of dimethylsiloxane (DMS) with ethylene or propylene oxide were tested as artificial carriers for the delivery of oxygen to biological systems. Copolymers with a DMS content of 33% or lower enhanced glucose oxidation by 200% in contrast to the 25% increase produced by the same concentration of perfluorodecalin. When 0.05% of the copolymer with 18% DMS was included in the growth media of Bacillus thuriginensis, the biomass (growth rate) increased 1.5-fold. With 0.1% of this copolymer, actinorhodin production by Streptomyces coelicolor A3 (2) occurred in half the normal time and with an increased yield. In conclusion, these PDMS copolymers are a good alternative to perfluorodecalin as oxygen carriers in biotechnological processes.}},
  author       = {{Dey, Estera and Norrlow, O and Liu, Yang}},
  issn         = {{1432-0614}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{187--191}},
  publisher    = {{Springer}},
  series       = {{Applied Microbiology and Biotechnology}},
  title        = {{Artificial carrier for oxygen supply in biological systems}},
  url          = {{http://dx.doi.org/10.1007/s00253-003-1454-9}},
  doi          = {{10.1007/s00253-003-1454-9}},
  volume       = {{64}},
  year         = {{2004}},
}