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A statistical score for assessing the quality of multiple sequence alignments.

Ahola, Virpi ; Aittokallio, Tero ; Vihinen, Mauno LU and Uusipaikka, Esa (2006) In BMC Bioinformatics 7.
Abstract
Multiple sequence alignment is the foundation of many important applications in bioinformatics that aim at detecting functionally important regions, predicting protein structures, building phylogenetic trees etc. Although the automatic construction of a multiple sequence alignment for a set of remotely related sequences cause a very challenging and error-prone task, many downstream analyses still rely heavily on the accuracy of the alignments.
Please use this url to cite or link to this publication:
author
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Computational Biology: methods
in
BMC Bioinformatics
volume
7
article number
484
publisher
BioMed Central
external identifiers
  • pmid:17081313
  • scopus:33845203823
ISSN
1471-2105
DOI
10.1186/1471-2105-7-484
language
English
LU publication?
no
id
abfc0cb4-89dc-418e-ba07-8622f92c12c9 (old id 3635332)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/17081313?dopt=Abstract
date added to LUP
2016-04-04 09:20:00
date last changed
2020-01-12 20:49:41
@article{abfc0cb4-89dc-418e-ba07-8622f92c12c9,
  abstract     = {Multiple sequence alignment is the foundation of many important applications in bioinformatics that aim at detecting functionally important regions, predicting protein structures, building phylogenetic trees etc. Although the automatic construction of a multiple sequence alignment for a set of remotely related sequences cause a very challenging and error-prone task, many downstream analyses still rely heavily on the accuracy of the alignments.},
  author       = {Ahola, Virpi and Aittokallio, Tero and Vihinen, Mauno and Uusipaikka, Esa},
  issn         = {1471-2105},
  language     = {eng},
  publisher    = {BioMed Central},
  series       = {BMC Bioinformatics},
  title        = {A statistical score for assessing the quality of multiple sequence alignments.},
  url          = {http://dx.doi.org/10.1186/1471-2105-7-484},
  doi          = {10.1186/1471-2105-7-484},
  volume       = {7},
  year         = {2006},
}