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Racial and Sociodemographic Differences of Semen Parameters Among US Men Undergoing a Semen Analysis

Glazer, Clara Helene; Li, Shufeng; Zhang, Chiyuan Amy; Giwercman, Aleksander LU ; Bonde, Jens Peter and Eisenberg, Michael L. (2019) In Urology 123. p.126-132
Abstract

Objective: To characterize sociodemographic differences in semen parameters among US men undergoing a semen analysis. Materials and Methods: Men who provided a semen sample were identified from insurance claims between 2007 and 2016. Differences in semen parameters were characterized according to age, race, education, and region. Mean semen parameters and proportions of men with suboptimal parameters were compared and risks of oligospermia and azoospermia were assessed by logistic regression. Results: Of the 7263 men included, most men were white (55.1%), Hispanic (20.2%), or Asian (10.2%). Asians had the highest mean semen concentrations (69.2 × 106/mL), whereas blacks had the lowest (51.3 × 106/mL). Men from the... (More)

Objective: To characterize sociodemographic differences in semen parameters among US men undergoing a semen analysis. Materials and Methods: Men who provided a semen sample were identified from insurance claims between 2007 and 2016. Differences in semen parameters were characterized according to age, race, education, and region. Mean semen parameters and proportions of men with suboptimal parameters were compared and risks of oligospermia and azoospermia were assessed by logistic regression. Results: Of the 7263 men included, most men were white (55.1%), Hispanic (20.2%), or Asian (10.2%). Asians had the highest mean semen concentrations (69.2 × 106/mL), whereas blacks had the lowest (51.3 × 106/mL). Men from the Midwest were more likely to have oligospermia (odds ratio [OR] 1.62; 95% confidence interval [CI] 1.34-1.94), whereas men from the West were less likely (OR 0.82; 95% CI 0.82-0.94) when compared with men from South. An association between education and sperm concentration was observed. For example, men with a high school diploma or less were more likely to have oligospermia (OR 1.09; 95% CI 0.95-1.26), whereas men with at least a bachelor degree were less likely (OR 0.87; 95% CI 0.76-1.0) when compared with men with less than a bachelor degree. Conclusion: As we observed differences in semen quality based on sociodemographic factors, these findings may have clinical implications as relying on a single reference value when guiding infertile couples may be problematic given these variations. Further work is warranted to understand the etiology of such differences and determine if different normative reference values may apply for different populations.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Urology
volume
123
pages
126 - 132
publisher
Elsevier
external identifiers
  • scopus:85056241440
ISSN
0090-4295
DOI
10.1016/j.urology.2018.09.029
language
English
LU publication?
yes
id
ac55de75-f096-44ee-8fa4-9859a6eaed72
date added to LUP
2018-11-23 11:10:41
date last changed
2019-02-20 11:37:26
@article{ac55de75-f096-44ee-8fa4-9859a6eaed72,
  abstract     = {<p>Objective: To characterize sociodemographic differences in semen parameters among US men undergoing a semen analysis. Materials and Methods: Men who provided a semen sample were identified from insurance claims between 2007 and 2016. Differences in semen parameters were characterized according to age, race, education, and region. Mean semen parameters and proportions of men with suboptimal parameters were compared and risks of oligospermia and azoospermia were assessed by logistic regression. Results: Of the 7263 men included, most men were white (55.1%), Hispanic (20.2%), or Asian (10.2%). Asians had the highest mean semen concentrations (69.2 × 10<sup>6</sup>/mL), whereas blacks had the lowest (51.3 × 10<sup>6</sup>/mL). Men from the Midwest were more likely to have oligospermia (odds ratio [OR] 1.62; 95% confidence interval [CI] 1.34-1.94), whereas men from the West were less likely (OR 0.82; 95% CI 0.82-0.94) when compared with men from South. An association between education and sperm concentration was observed. For example, men with a high school diploma or less were more likely to have oligospermia (OR 1.09; 95% CI 0.95-1.26), whereas men with at least a bachelor degree were less likely (OR 0.87; 95% CI 0.76-1.0) when compared with men with less than a bachelor degree. Conclusion: As we observed differences in semen quality based on sociodemographic factors, these findings may have clinical implications as relying on a single reference value when guiding infertile couples may be problematic given these variations. Further work is warranted to understand the etiology of such differences and determine if different normative reference values may apply for different populations.</p>},
  author       = {Glazer, Clara Helene and Li, Shufeng and Zhang, Chiyuan Amy and Giwercman, Aleksander and Bonde, Jens Peter and Eisenberg, Michael L.},
  issn         = {0090-4295},
  language     = {eng},
  pages        = {126--132},
  publisher    = {Elsevier},
  series       = {Urology},
  title        = {Racial and Sociodemographic Differences of Semen Parameters Among US Men Undergoing a Semen Analysis},
  url          = {http://dx.doi.org/10.1016/j.urology.2018.09.029},
  volume       = {123},
  year         = {2019},
}