International Society of Blood Transfusion Working Party on Red Cell Immunogenetics and Blood Group Terminology Report of Basel and three virtual business meetings : Update on blood group systems
(2022) In Vox Sanguinis 117(11). p.1332-1344- Abstract
BACKGROUND AND OBJECTIVES: Under the ISBT, the Working Party (WP) for Red Cell Immunogenetics and Blood Group Terminology is charged with ratifying blood group systems, antigens and alleles. This report presents the outcomes from four WP business meetings, one located in Basel in 2019 and three held as virtual meetings during the COVID-19 pandemic in 2020 and 2021.
MATERIALS AND METHODS: As in previous meetings, matters pertaining to blood group antigen nomenclature were discussed. New blood group systems and antigens were approved and named according to the serologic, genetic, biochemical and cell biological evidence presented.
RESULTS: Seven new blood group systems, KANNO (defined numerically as ISBT 037), SID (038), CTL2... (More)
BACKGROUND AND OBJECTIVES: Under the ISBT, the Working Party (WP) for Red Cell Immunogenetics and Blood Group Terminology is charged with ratifying blood group systems, antigens and alleles. This report presents the outcomes from four WP business meetings, one located in Basel in 2019 and three held as virtual meetings during the COVID-19 pandemic in 2020 and 2021.
MATERIALS AND METHODS: As in previous meetings, matters pertaining to blood group antigen nomenclature were discussed. New blood group systems and antigens were approved and named according to the serologic, genetic, biochemical and cell biological evidence presented.
RESULTS: Seven new blood group systems, KANNO (defined numerically as ISBT 037), SID (038), CTL2 (039), PEL (040), MAM (041), EMM (042) and ABCC1 (043) were ratified. Two (039 and 043) were de novo discoveries, and the remainder comprised reported antigens where the causal genes were previously unknown. A further 15 blood group antigens were added to the existing blood group systems: MNS (002), RH (004), LU (005), DI (010), SC (013), GE (020), KN (022), JMH (026) and RHAG (030).
CONCLUSION: The ISBT now recognizes 378 antigens, of which 345 are clustered within 43 blood group systems while 33 still have an unknown genetic basis. The ongoing discovery of new blood group systems and antigens underscores the diverse and complex biology of the red cell membrane. The WP continues to update the blood group antigen tables and the allele nomenclature tables. These can be found on the ISBT website (http://www.isbtweb.org/working-parties/red-cell-immunogenetics-and-blood-group-terminology/).
(Less)
- author
- Gassner, Christoph
; Castilho, Lilian
; Chen, Qing
; Clausen, Frederik Banch
; Denomme, Gregory A
; Flegel, Willy A
; Gleadall, Nick
; Hellberg, Åsa
LU
; Ji, Yanli
; Keller, Margaret A
; Lane, William J
; Ligthart, Peter
; Lomas-Francis, Christine
; Nogues, Nuria
; Olsson, Martin L
LU
; Peyrard, Thierry
; Storry, Jill R
LU
; Tani, Yoshihiko
; Thornton, Nicole
; van der Schoot, Ellen
; Veldhuisen, Barbera
; Wagner, Franz
; Weinstock, Christof
; Wendel, Silvano
; Westhoff, Connie
; Yahalom, Vered
and Hyland, Catherine A
(Less) - organization
- publishing date
- 2022-09-19
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Vox Sanguinis
- volume
- 117
- issue
- 11
- pages
- 1332 - 1344
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:36121188
- scopus:85138239687
- ISSN
- 1423-0410
- DOI
- 10.1111/vox.13361
- language
- English
- LU publication?
- yes
- additional info
- © 2022 International Society of Blood Transfusion.
- id
- acc11724-d54a-434f-9928-65064b3b4645
- date added to LUP
- 2022-10-30 15:13:31
- date last changed
- 2024-04-17 04:06:29
@article{acc11724-d54a-434f-9928-65064b3b4645,
abstract = {{<p>BACKGROUND AND OBJECTIVES: Under the ISBT, the Working Party (WP) for Red Cell Immunogenetics and Blood Group Terminology is charged with ratifying blood group systems, antigens and alleles. This report presents the outcomes from four WP business meetings, one located in Basel in 2019 and three held as virtual meetings during the COVID-19 pandemic in 2020 and 2021.</p><p>MATERIALS AND METHODS: As in previous meetings, matters pertaining to blood group antigen nomenclature were discussed. New blood group systems and antigens were approved and named according to the serologic, genetic, biochemical and cell biological evidence presented.</p><p>RESULTS: Seven new blood group systems, KANNO (defined numerically as ISBT 037), SID (038), CTL2 (039), PEL (040), MAM (041), EMM (042) and ABCC1 (043) were ratified. Two (039 and 043) were de novo discoveries, and the remainder comprised reported antigens where the causal genes were previously unknown. A further 15 blood group antigens were added to the existing blood group systems: MNS (002), RH (004), LU (005), DI (010), SC (013), GE (020), KN (022), JMH (026) and RHAG (030).</p><p>CONCLUSION: The ISBT now recognizes 378 antigens, of which 345 are clustered within 43 blood group systems while 33 still have an unknown genetic basis. The ongoing discovery of new blood group systems and antigens underscores the diverse and complex biology of the red cell membrane. The WP continues to update the blood group antigen tables and the allele nomenclature tables. These can be found on the ISBT website (http://www.isbtweb.org/working-parties/red-cell-immunogenetics-and-blood-group-terminology/).</p>}},
author = {{Gassner, Christoph and Castilho, Lilian and Chen, Qing and Clausen, Frederik Banch and Denomme, Gregory A and Flegel, Willy A and Gleadall, Nick and Hellberg, Åsa and Ji, Yanli and Keller, Margaret A and Lane, William J and Ligthart, Peter and Lomas-Francis, Christine and Nogues, Nuria and Olsson, Martin L and Peyrard, Thierry and Storry, Jill R and Tani, Yoshihiko and Thornton, Nicole and van der Schoot, Ellen and Veldhuisen, Barbera and Wagner, Franz and Weinstock, Christof and Wendel, Silvano and Westhoff, Connie and Yahalom, Vered and Hyland, Catherine A}},
issn = {{1423-0410}},
language = {{eng}},
month = {{09}},
number = {{11}},
pages = {{1332--1344}},
publisher = {{Wiley-Blackwell}},
series = {{Vox Sanguinis}},
title = {{International Society of Blood Transfusion Working Party on Red Cell Immunogenetics and Blood Group Terminology Report of Basel and three virtual business meetings : Update on blood group systems}},
url = {{http://dx.doi.org/10.1111/vox.13361}},
doi = {{10.1111/vox.13361}},
volume = {{117}},
year = {{2022}},
}