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International Forum on Policies and Practice for Transfusion of ABO and RhD Non-Identical Platelets : Summary

Cardigan, Rebecca ; New, Helen V ; Estcourt, Lise ; Zhiburt, Eugene ; Dubey, Rounak ; Bengtsson, Jesper ; Jöud, Magnus LU orcid ; Castillo, Carlos ; Cid, Joan and Lozano, Miquel , et al. (2022) In Vox Sanguinis 117(1). p.136-144
Abstract
Transfusion of ABO major incompatible platelets (where the recipient has antibodies against the ABO group of the transfused platelets) has been shown to be associated with lower platelet count increments following transfusion [1], although this does not appear to translate to a difference in bleeding outcomes [2]. Transfusion of minor ABO incompatible platelets (where the suspending plasma of the platelet concentrate is not compatible with the ABO group of the recipient's red cells) has been associated with increased risk of haemolytic transfusion reactions. This risk is likely to be lower for platelets stored in platelet additive solution due to the reduced volume of plasma.

Please use this url to cite or link to this publication:
@article{ad6cae7b-f7af-4b1a-8156-72d12aba8e6b,
  abstract     = {{Transfusion of ABO major incompatible platelets (where the recipient has antibodies against the ABO group of the transfused platelets) has been shown to be associated with lower platelet count increments following transfusion [1], although this does not appear to translate to a difference in bleeding outcomes [2]. Transfusion of minor ABO incompatible platelets (where the suspending plasma of the platelet concentrate is not compatible with the ABO group of the recipient's red cells) has been associated with increased risk of haemolytic transfusion reactions. This risk is likely to be lower for platelets stored in platelet additive solution due to the reduced volume of plasma.<br/><br/>}},
  author       = {{Cardigan, Rebecca and New, Helen V and Estcourt, Lise and Zhiburt, Eugene and Dubey, Rounak and Bengtsson, Jesper and Jöud, Magnus and Castillo, Carlos and Cid, Joan and Lozano, Miquel and Gounder, Dhana and Flanagan, Peter and Morley, Sarah and Clarke, Gwen and Devine, Dana and Hindawi, Salwa and AlOtaibi, Aqeel and Bub, Carolina Bonnet and Kutner, Jose Mauro and Ikeda, Toshiyuki and Goto, Naoko and Okazaki, Hitoshi and Fontaine, Magali J and Pasion, Jeremiah and Song, Linda and Latham, Tom and Kerkhoffs, Jean-Louis and de Haas, Masja and Zwaginga, Jaap Jan and Gathof, Birgit S and Ommer, Katharina and Pirenne, France and Raba, Michel and Francois, Anne and Daly, James and Powley, Tanya and Dunbar, Nancy}},
  issn         = {{1423-0410}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{136--144}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Vox Sanguinis}},
  title        = {{International Forum on Policies and Practice for Transfusion of ABO and RhD Non-Identical Platelets : Summary}},
  url          = {{http://dx.doi.org/10.1111/vox.13129}},
  doi          = {{10.1111/vox.13129}},
  volume       = {{117}},
  year         = {{2022}},
}