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Cancer - An Insurgency of Clones

Gisselsson, David LU and Egnell, Robert (2017) In Trends in Cancer Reserach 3(2). p.73-75
Abstract

Oncological therapy resembles a military force that eliminates the central power of a country (dominant clone of a cancer) to create a vacuum where insurgents (subclones) thrive and instigate rebellion (relapse). We suggest that military counterinsurgency doctrine can inspire a discussion of cancer that uniquely embraces both cancer cell evolution and tumour microenvironment.

Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Cancer, Counterinsurgency, Evolution, Microenvironment
in
Trends in Cancer Reserach
volume
3
issue
2
pages
73 - 75
publisher
Cell Press
external identifiers
  • scopus:85009251532
ISSN
2405-8033
DOI
10.1016/j.trecan.2016.11.010
language
English
LU publication?
yes
id
ae02238f-5d4b-4153-95ad-b84694c4dce0
date added to LUP
2017-02-10 14:22:17
date last changed
2018-01-07 11:49:16
@article{ae02238f-5d4b-4153-95ad-b84694c4dce0,
  abstract     = {<p>Oncological therapy resembles a military force that eliminates the central power of a country (dominant clone of a cancer) to create a vacuum where insurgents (subclones) thrive and instigate rebellion (relapse). We suggest that military counterinsurgency doctrine can inspire a discussion of cancer that uniquely embraces both cancer cell evolution and tumour microenvironment.</p>},
  author       = {Gisselsson, David and Egnell, Robert},
  issn         = {2405-8033},
  keyword      = {Cancer,Counterinsurgency,Evolution,Microenvironment},
  language     = {eng},
  number       = {2},
  pages        = {73--75},
  publisher    = {Cell Press},
  series       = {Trends in Cancer Reserach},
  title        = {Cancer - An Insurgency of Clones},
  url          = {http://dx.doi.org/10.1016/j.trecan.2016.11.010},
  volume       = {3},
  year         = {2017},
}