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Cancer - An Insurgency of Clones

Gisselsson, David LU and Egnell, Robert (2017) In Trends in Cancer 3(2). p.73-75
Abstract

Oncological therapy resembles a military force that eliminates the central power of a country (dominant clone of a cancer) to create a vacuum where insurgents (subclones) thrive and instigate rebellion (relapse). We suggest that military counterinsurgency doctrine can inspire a discussion of cancer that uniquely embraces both cancer cell evolution and tumour microenvironment.

Please use this url to cite or link to this publication:
author
and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Cancer, Counterinsurgency, Evolution, Microenvironment
in
Trends in Cancer
volume
3
issue
2
pages
73 - 75
publisher
Cell Press
external identifiers
  • scopus:85009251532
  • pmid:28718446
ISSN
2405-8033
DOI
10.1016/j.trecan.2016.11.010
language
English
LU publication?
yes
id
ae02238f-5d4b-4153-95ad-b84694c4dce0
date added to LUP
2017-02-10 14:22:17
date last changed
2024-03-17 07:32:45
@article{ae02238f-5d4b-4153-95ad-b84694c4dce0,
  abstract     = {{<p>Oncological therapy resembles a military force that eliminates the central power of a country (dominant clone of a cancer) to create a vacuum where insurgents (subclones) thrive and instigate rebellion (relapse). We suggest that military counterinsurgency doctrine can inspire a discussion of cancer that uniquely embraces both cancer cell evolution and tumour microenvironment.</p>}},
  author       = {{Gisselsson, David and Egnell, Robert}},
  issn         = {{2405-8033}},
  keywords     = {{Cancer; Counterinsurgency; Evolution; Microenvironment}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{73--75}},
  publisher    = {{Cell Press}},
  series       = {{Trends in Cancer}},
  title        = {{Cancer - An Insurgency of Clones}},
  url          = {{http://dx.doi.org/10.1016/j.trecan.2016.11.010}},
  doi          = {{10.1016/j.trecan.2016.11.010}},
  volume       = {{3}},
  year         = {{2017}},
}