Cancer - An Insurgency of Clones
(2017) In Trends in Cancer 3(2). p.73-75- Abstract
Oncological therapy resembles a military force that eliminates the central power of a country (dominant clone of a cancer) to create a vacuum where insurgents (subclones) thrive and instigate rebellion (relapse). We suggest that military counterinsurgency doctrine can inspire a discussion of cancer that uniquely embraces both cancer cell evolution and tumour microenvironment.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/ae02238f-5d4b-4153-95ad-b84694c4dce0
- author
- Gisselsson, David LU and Egnell, Robert
- organization
- publishing date
- 2017
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Cancer, Counterinsurgency, Evolution, Microenvironment
- in
- Trends in Cancer
- volume
- 3
- issue
- 2
- pages
- 73 - 75
- publisher
- Cell Press
- external identifiers
-
- scopus:85009251532
- pmid:28718446
- ISSN
- 2405-8033
- DOI
- 10.1016/j.trecan.2016.11.010
- language
- English
- LU publication?
- yes
- id
- ae02238f-5d4b-4153-95ad-b84694c4dce0
- date added to LUP
- 2017-02-10 14:22:17
- date last changed
- 2024-10-13 23:32:56
@article{ae02238f-5d4b-4153-95ad-b84694c4dce0,
abstract = {{<p>Oncological therapy resembles a military force that eliminates the central power of a country (dominant clone of a cancer) to create a vacuum where insurgents (subclones) thrive and instigate rebellion (relapse). We suggest that military counterinsurgency doctrine can inspire a discussion of cancer that uniquely embraces both cancer cell evolution and tumour microenvironment.</p>}},
author = {{Gisselsson, David and Egnell, Robert}},
issn = {{2405-8033}},
keywords = {{Cancer; Counterinsurgency; Evolution; Microenvironment}},
language = {{eng}},
number = {{2}},
pages = {{73--75}},
publisher = {{Cell Press}},
series = {{Trends in Cancer}},
title = {{Cancer - An Insurgency of Clones}},
url = {{http://dx.doi.org/10.1016/j.trecan.2016.11.010}},
doi = {{10.1016/j.trecan.2016.11.010}},
volume = {{3}},
year = {{2017}},
}