Inhaled dsRNA and rhinovirus evoke neutrophilic exacerbation and lung expression of thymic stromal lymphopoietin in allergic mice with established experimental asthma.
(2014) In Allergy 69(3). p.348-358- Abstract
- Rhinovirus infection or dsRNA stimulation increased thymic stromal lymphopoietin (TSLP), an upstream pro-allergic cytokine, in asthmatic bronchial epithelial cells. We hypothesized that dsRNA challenges superimposed on established experimental allergic asthma constitute a useful exacerbation model. We further hypothesized that TSLP is induced at dsRNA- and rhinoviral infection-induced exacerbations.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4178864
- author
- Mahmutovic Persson, Irma LU ; Akbarshahi, Hamid LU ; Bartlett, N W ; Glanville, N ; Johnston, S L ; Brandelius, Angelica LU and Uller, Lena LU
- organization
- publishing date
- 2014
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Allergy
- volume
- 69
- issue
- 3
- pages
- 348 - 358
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:24283976
- wos:000331358400008
- scopus:84894267969
- pmid:24283976
- ISSN
- 1398-9995
- DOI
- 10.1111/all.12329
- language
- English
- LU publication?
- yes
- id
- ae2164bf-c191-4267-a6bb-5898e6bcc015 (old id 4178864)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/24283976?dopt=Abstract
- date added to LUP
- 2016-04-01 10:52:51
- date last changed
- 2022-04-06 13:37:18
@article{ae2164bf-c191-4267-a6bb-5898e6bcc015, abstract = {{Rhinovirus infection or dsRNA stimulation increased thymic stromal lymphopoietin (TSLP), an upstream pro-allergic cytokine, in asthmatic bronchial epithelial cells. We hypothesized that dsRNA challenges superimposed on established experimental allergic asthma constitute a useful exacerbation model. We further hypothesized that TSLP is induced at dsRNA- and rhinoviral infection-induced exacerbations.}}, author = {{Mahmutovic Persson, Irma and Akbarshahi, Hamid and Bartlett, N W and Glanville, N and Johnston, S L and Brandelius, Angelica and Uller, Lena}}, issn = {{1398-9995}}, language = {{eng}}, number = {{3}}, pages = {{348--358}}, publisher = {{Wiley-Blackwell}}, series = {{Allergy}}, title = {{Inhaled dsRNA and rhinovirus evoke neutrophilic exacerbation and lung expression of thymic stromal lymphopoietin in allergic mice with established experimental asthma.}}, url = {{http://dx.doi.org/10.1111/all.12329}}, doi = {{10.1111/all.12329}}, volume = {{69}}, year = {{2014}}, }