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Primär hyperparatyreoidism vanligt hos postmenopausala kvinnor. Identifiering av genetiska riskfaktorer kan ge individanpassad behandling

Correa, Pamela LU ; Szabo, Eva ; Lundgren, Ewa and Carling, Tobias (2001) In Lakartidningen 98(18). p.200-2198
Abstract

Primary hyperparathyroidism (pHPT) is commonly seen in postmenopausal women. Along with the clinical characterisation of the disease, studies of molecular genetics have contributed to increased understanding of the etiology of pHPT. Genetic association studies have revealed that certain vitamin D receptor polymorphisms relate to the development of sporadic pHPT. A new type of familial pHPT was recently discovered. Studies of parathyroid adenomas have demonstrated that the tumor suppressor gene MEN1 and the oncogene cyclinD1 are of importance for the tumorigenesis.

Please use this url to cite or link to this publication:
author
; ; and
alternative title
Primary hyperparathyroidism is common among postmenopausal women. Identification of genetic risk factors can contribute to individualized treatment
publishing date
type
Contribution to specialist publication or newspaper
publication status
published
keywords
Aged, Calcium/metabolism, Female, Genes, bcl-1, Genetic Predisposition to Disease, Humans, Hyperparathyroidism/diagnosis, Middle Aged, Parathyroid Hormone/genetics, Postmenopause, Risk Factors
in
Lakartidningen
volume
98
issue
18
pages
200 - 2198
publisher
Swedish Medical Association
external identifiers
  • pmid:11402599
  • scopus:0035795832
ISSN
0023-7205
language
Swedish
LU publication?
no
id
ae4b20db-4cc5-4714-9819-06e7616577d0
alternative location
https://lakartidningen.se/wp-content/uploads/OldPdfFiles/2001/22869.pdf
date added to LUP
2021-12-29 12:27:18
date last changed
2024-01-05 23:28:08
@misc{ae4b20db-4cc5-4714-9819-06e7616577d0,
  abstract     = {{<p>Primary hyperparathyroidism (pHPT) is commonly seen in postmenopausal women. Along with the clinical characterisation of the disease, studies of molecular genetics have contributed to increased understanding of the etiology of pHPT. Genetic association studies have revealed that certain vitamin D receptor polymorphisms relate to the development of sporadic pHPT. A new type of familial pHPT was recently discovered. Studies of parathyroid adenomas have demonstrated that the tumor suppressor gene MEN1 and the oncogene cyclinD1 are of importance for the tumorigenesis.</p>}},
  author       = {{Correa, Pamela and Szabo, Eva and Lundgren, Ewa and Carling, Tobias}},
  issn         = {{0023-7205}},
  keywords     = {{Aged; Calcium/metabolism; Female; Genes, bcl-1; Genetic Predisposition to Disease; Humans; Hyperparathyroidism/diagnosis; Middle Aged; Parathyroid Hormone/genetics; Postmenopause; Risk Factors}},
  language     = {{swe}},
  number       = {{18}},
  pages        = {{200--2198}},
  publisher    = {{Swedish Medical Association}},
  series       = {{Lakartidningen}},
  title        = {{Primär hyperparatyreoidism vanligt hos postmenopausala kvinnor. Identifiering av genetiska riskfaktorer kan ge individanpassad behandling}},
  url          = {{https://lakartidningen.se/wp-content/uploads/OldPdfFiles/2001/22869.pdf}},
  volume       = {{98}},
  year         = {{2001}},
}