Advanced

Velocity and asymmetry of optokinetic nystagmus in the evaluation of vestibular lesions

Magnusson, M LU and Pyykkö, I. (1986) In Acta oto-laryngologica 102(1-2). p.65-74
Abstract

Optokinetic nystagmus (OKN) at a constant stimulus velocity of 90 degrees/s was studied in 50 healthy subjects and three different groups of patients: 10 with vestibular neuritis (VN), 17 with unilateral infratentorial lesion (UI) and 13 patients with bilateral infratentorial lesion (BI). Among healthy subjects, OKN decreased with age in those over 42 and 44 years for maximum and mean velocity, respectively. The maximum velocity of OKN discriminated between the healthy subjects and the groups of patients rather better than did mean velocity of OKN. Asymmetry of either mean or maximum velocity contributed only marginally to correct group assignment. By subjecting test data on velocity and asymmetry variables to linear discriminant... (More)

Optokinetic nystagmus (OKN) at a constant stimulus velocity of 90 degrees/s was studied in 50 healthy subjects and three different groups of patients: 10 with vestibular neuritis (VN), 17 with unilateral infratentorial lesion (UI) and 13 patients with bilateral infratentorial lesion (BI). Among healthy subjects, OKN decreased with age in those over 42 and 44 years for maximum and mean velocity, respectively. The maximum velocity of OKN discriminated between the healthy subjects and the groups of patients rather better than did mean velocity of OKN. Asymmetry of either mean or maximum velocity contributed only marginally to correct group assignment. By subjecting test data on velocity and asymmetry variables to linear discriminant function analysis, 80% of subjects could be correctly classified as healthy/not healthy, and 64% assigned to the correct group according to diagnosis. Analysis of OKN data satisfactorily discriminated BI and UI patients from VN patients and healthy subjects, and is thus useful in assessing infratentorial vestibular lesions.

(Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Adolescent, Adult, Aged, Electrooculography, Humans, Middle Aged, Neuritis, Nystagmus, Physiologic, Reference Values, Regression Analysis, Vestibular Nerve, Vestibulocochlear Nerve Diseases, Comparative Study, Journal Article
in
Acta oto-laryngologica
volume
102
issue
1-2
pages
10 pages
publisher
Taylor & Francis
external identifiers
  • scopus:0022878403
ISSN
0001-6489
language
English
LU publication?
yes
id
ae770162-9332-446f-b794-1f17101f0b01
date added to LUP
2017-05-03 13:06:01
date last changed
2017-05-07 04:53:08
@article{ae770162-9332-446f-b794-1f17101f0b01,
  abstract     = {<p>Optokinetic nystagmus (OKN) at a constant stimulus velocity of 90 degrees/s was studied in 50 healthy subjects and three different groups of patients: 10 with vestibular neuritis (VN), 17 with unilateral infratentorial lesion (UI) and 13 patients with bilateral infratentorial lesion (BI). Among healthy subjects, OKN decreased with age in those over 42 and 44 years for maximum and mean velocity, respectively. The maximum velocity of OKN discriminated between the healthy subjects and the groups of patients rather better than did mean velocity of OKN. Asymmetry of either mean or maximum velocity contributed only marginally to correct group assignment. By subjecting test data on velocity and asymmetry variables to linear discriminant function analysis, 80% of subjects could be correctly classified as healthy/not healthy, and 64% assigned to the correct group according to diagnosis. Analysis of OKN data satisfactorily discriminated BI and UI patients from VN patients and healthy subjects, and is thus useful in assessing infratentorial vestibular lesions.</p>},
  author       = {Magnusson, M and Pyykkö, I.},
  issn         = {0001-6489},
  keyword      = {Adolescent,Adult,Aged,Electrooculography,Humans,Middle Aged,Neuritis,Nystagmus, Physiologic,Reference Values,Regression Analysis,Vestibular Nerve,Vestibulocochlear Nerve Diseases,Comparative Study,Journal Article},
  language     = {eng},
  month        = {07},
  number       = {1-2},
  pages        = {65--74},
  publisher    = {Taylor & Francis},
  series       = {Acta oto-laryngologica},
  title        = {Velocity and asymmetry of optokinetic nystagmus in the evaluation of vestibular lesions},
  volume       = {102},
  year         = {1986},
}