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Evaluation of a flat fielding method for simultaneous DBT and MI acquisition

Bakic, Predrag R. LU ; Dustler, Magnus LU ; Lau, Kristen C. ; Maidment, Andrew D.A. ; Zackrisson, Sophia LU and Tingberg, Anders LU (2020) 15th International Workshop on Breast Imaging, IWBI 2020 In Proceedings of SPIE - The International Society for Optical Engineering 11513.
Abstract

We are developing a prototype system for simultaneous digital breast tomosynthesis (DBT) and mechanical imaging (MI). MI maps the local pressure distribution during clinical exams, to distinguish breast abnormalities from the normal tissue. Both DBT alone, and MI when combined with digital mammography, have demonstrated the ability to reduce false positives; however, the benefit of combining DBT with MI has not been investigated. A practical limitation in simultaneous DBT and MI is the presence of the MI sensor in DBT images. Metallic elements of the sensor generate noticeable artifacts, which may interfere with clinical analysis. Previously, we shown that the sensor artifacts can be reduced by flat fielding, which combines projections... (More)

We are developing a prototype system for simultaneous digital breast tomosynthesis (DBT) and mechanical imaging (MI). MI maps the local pressure distribution during clinical exams, to distinguish breast abnormalities from the normal tissue. Both DBT alone, and MI when combined with digital mammography, have demonstrated the ability to reduce false positives; however, the benefit of combining DBT with MI has not been investigated. A practical limitation in simultaneous DBT and MI is the presence of the MI sensor in DBT images. Metallic elements of the sensor generate noticeable artifacts, which may interfere with clinical analysis. Previously, we shown that the sensor artifacts can be reduced by flat fielding, which combines projections of the sensor acquired with and without the breast. In this paper we evaluate the flat fielding by assessing artifact reduction and visibility of breast abnormalities. Images of a physical anthropomorphic breast phantom were acquired using a clinical wide-angle DBT system. Visual evaluation was performed by experienced medical physicists. Image quality descriptors were calculated in images with and without flat fielding. To evaluate the visibility of abnormalities we estimated the full width at half maximum (FWHM) for calcifications modeled in the phantom. Our preliminary results suggest a substantial reduction of artifacts by flat fielding (on average 83%). Few noticeable artifacts remain near the breast edge, in the reconstructed image with the sensor in focus. We observed a 17% reduction in the FWHM. Future work would include a detailed assessment, and method optimization using virtual trials as a design aid.

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Please use this url to cite or link to this publication:
author
; ; ; ; and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Artifact reduction, Digital breast tomosynthesis, Flat fielding, Image quality evaluation, Mechanical imaging, Multimodality breast imaging
host publication
15th International Workshop on Breast Imaging, IWBI 2020
series title
Proceedings of SPIE - The International Society for Optical Engineering
editor
Bosmans, Hilde ; Marshall, Nicholas and Van Ongeval, Chantal
volume
11513
article number
115130U
publisher
SPIE
conference name
15th International Workshop on Breast Imaging, IWBI 2020
conference location
Leuven, Belgium
conference dates
2020-05-25 - 2020-05-27
external identifiers
  • scopus:85086138999
ISSN
0277-786X
1996-756X
ISBN
9781510638310
DOI
10.1117/12.2564377
project
Simultaneous Digital Breast Tomosynthesis and Mechanical Imaging
language
English
LU publication?
yes
id
aec89b91-4b77-4980-bd20-ae2a5b7d3528
date added to LUP
2021-01-11 12:21:05
date last changed
2024-03-20 23:09:04
@inproceedings{aec89b91-4b77-4980-bd20-ae2a5b7d3528,
  abstract     = {{<p>We are developing a prototype system for simultaneous digital breast tomosynthesis (DBT) and mechanical imaging (MI). MI maps the local pressure distribution during clinical exams, to distinguish breast abnormalities from the normal tissue. Both DBT alone, and MI when combined with digital mammography, have demonstrated the ability to reduce false positives; however, the benefit of combining DBT with MI has not been investigated. A practical limitation in simultaneous DBT and MI is the presence of the MI sensor in DBT images. Metallic elements of the sensor generate noticeable artifacts, which may interfere with clinical analysis. Previously, we shown that the sensor artifacts can be reduced by flat fielding, which combines projections of the sensor acquired with and without the breast. In this paper we evaluate the flat fielding by assessing artifact reduction and visibility of breast abnormalities. Images of a physical anthropomorphic breast phantom were acquired using a clinical wide-angle DBT system. Visual evaluation was performed by experienced medical physicists. Image quality descriptors were calculated in images with and without flat fielding. To evaluate the visibility of abnormalities we estimated the full width at half maximum (FWHM) for calcifications modeled in the phantom. Our preliminary results suggest a substantial reduction of artifacts by flat fielding (on average 83%). Few noticeable artifacts remain near the breast edge, in the reconstructed image with the sensor in focus. We observed a 17% reduction in the FWHM. Future work would include a detailed assessment, and method optimization using virtual trials as a design aid.</p>}},
  author       = {{Bakic, Predrag R. and Dustler, Magnus and Lau, Kristen C. and Maidment, Andrew D.A. and Zackrisson, Sophia and Tingberg, Anders}},
  booktitle    = {{15th International Workshop on Breast Imaging, IWBI 2020}},
  editor       = {{Bosmans, Hilde and Marshall, Nicholas and Van Ongeval, Chantal}},
  isbn         = {{9781510638310}},
  issn         = {{0277-786X}},
  keywords     = {{Artifact reduction; Digital breast tomosynthesis; Flat fielding; Image quality evaluation; Mechanical imaging; Multimodality breast imaging}},
  language     = {{eng}},
  publisher    = {{SPIE}},
  series       = {{Proceedings of SPIE - The International Society for Optical Engineering}},
  title        = {{Evaluation of a flat fielding method for simultaneous DBT and MI acquisition}},
  url          = {{http://dx.doi.org/10.1117/12.2564377}},
  doi          = {{10.1117/12.2564377}},
  volume       = {{11513}},
  year         = {{2020}},
}