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Reaction of pyridine N-oxides with Grignard reagents : a stereodefined synthesis of substituted dienal oximes

Andersson, Hans ; Wang, Xiaoyang ; Björklund, Mikael ; Olsson, Roger LU and Almqvist, Fredrik (2007) In Tetrahedron Letters 48(39). p.6941-6944
Abstract

Rapid addition of Grignard reagents to pyridine N-oxides under mild conditions gave stereodefined dienal oximes in good to excellent yields. This reaction provides an efficient access to substituted olefins with defined stereochemistry that are potentially of interest as bioactives themselves or as versatile synthetic intermediates.

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author
; ; ; and
publishing date
type
Contribution to journal
publication status
published
subject
in
Tetrahedron Letters
volume
48
issue
39
pages
6941 - 6944
publisher
Elsevier
external identifiers
  • scopus:34548230025
ISSN
0040-4039
DOI
10.1016/j.tetlet.2007.07.161
language
English
LU publication?
no
id
aed564ab-0be9-4465-a70a-43dc4715d1cf
date added to LUP
2019-10-02 10:26:08
date last changed
2020-10-07 06:44:04
@article{aed564ab-0be9-4465-a70a-43dc4715d1cf,
  abstract     = {<p>Rapid addition of Grignard reagents to pyridine N-oxides under mild conditions gave stereodefined dienal oximes in good to excellent yields. This reaction provides an efficient access to substituted olefins with defined stereochemistry that are potentially of interest as bioactives themselves or as versatile synthetic intermediates.</p>},
  author       = {Andersson, Hans and Wang, Xiaoyang and Björklund, Mikael and Olsson, Roger and Almqvist, Fredrik},
  issn         = {0040-4039},
  language     = {eng},
  month        = {09},
  number       = {39},
  pages        = {6941--6944},
  publisher    = {Elsevier},
  series       = {Tetrahedron Letters},
  title        = {Reaction of pyridine N-oxides with Grignard reagents : a stereodefined synthesis of substituted dienal oximes},
  url          = {http://dx.doi.org/10.1016/j.tetlet.2007.07.161},
  doi          = {10.1016/j.tetlet.2007.07.161},
  volume       = {48},
  year         = {2007},
}