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Correspondence between clinical diagnoses of depressive and anxiety disorders and diagnostic screening via the Hopkins Symptom Check List-25 in the Lundby Study.

Mattisson, Cecilia LU ; Bogren, Mats LU and Horstmann, Vibeke LU (2013) In Nordic Journal of Psychiatry 67(3). p.204-213
Abstract
Aim:

To compare clinical assessments of mental disorders with the Hopkins Symptom Check List-25 (HSCL-25) in a population-based sample consisting of middle-aged and elderly subjects.



Background:

The Lundby Study is a prospective cohort study that evaluated mental disorders and personality traits in an unselected Swedish population. The study commenced in 1947, with follow-ups in 1957, 1972 and 1997 (n = 3563).



Method:

Psychiatrists evaluated participants for mental disorders at several field investigations. In 1997, participants were also asked to complete the HSCL-25. Subjects with diagnoses of schizophrenia, dementia and certain other conditions were excluded leaving... (More)
Aim:

To compare clinical assessments of mental disorders with the Hopkins Symptom Check List-25 (HSCL-25) in a population-based sample consisting of middle-aged and elderly subjects.



Background:

The Lundby Study is a prospective cohort study that evaluated mental disorders and personality traits in an unselected Swedish population. The study commenced in 1947, with follow-ups in 1957, 1972 and 1997 (n = 3563).



Method:

Psychiatrists evaluated participants for mental disorders at several field investigations. In 1997, participants were also asked to complete the HSCL-25. Subjects with diagnoses of schizophrenia, dementia and certain other conditions were excluded leaving 1189 subjects aged 40-96 years. Diagnostic assessments by psychiatrists were compared with the results of the HSCL-25. Sensitivity and specificity were calculated at two cut-off levels of the HSCL-25 (1.55 and 1.75), and receiver operating characteristic (ROC) curves were plotted. The performance of the HSCL-25 was analysed with regard to anxiety and depression subscales.



Results:

The concordance of HSCL-25 with clinical best-estimate diagnoses was low. The anxiety subscale discriminated better than the depressive subscale.



Conclusions:

The correspondence between the clinical diagnoses made by psychiatrists and the HSCL-25 was not acceptable at a cut-off level 1.55. The HSCL-25 is limited in its ability to identify clinical syndromes. The HSCL-25 should be applied only as a preliminary screen for emotional distress and anxiety syndromes. (Less)
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author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Nordic Journal of Psychiatry
volume
67
issue
3
pages
204 - 213
publisher
Informa Healthcare
external identifiers
  • wos:000319077800010
  • pmid:22906095
  • scopus:84878076691
  • pmid:22906095
ISSN
1502-4725
DOI
10.3109/08039488.2012.711856
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Division of Occupational Therapy (Closed 2012) (013025000), Psychiatry (Lund) (013303000)
id
af229d08-3d56-482d-b6cf-0d3c30d2dd1b (old id 3047366)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/22906095?dopt=Abstract
date added to LUP
2016-04-01 09:48:03
date last changed
2022-04-03 23:24:54
@article{af229d08-3d56-482d-b6cf-0d3c30d2dd1b,
  abstract     = {{Aim: <br/><br>
To compare clinical assessments of mental disorders with the Hopkins Symptom Check List-25 (HSCL-25) in a population-based sample consisting of middle-aged and elderly subjects. <br/><br>
<br/><br>
Background: <br/><br>
The Lundby Study is a prospective cohort study that evaluated mental disorders and personality traits in an unselected Swedish population. The study commenced in 1947, with follow-ups in 1957, 1972 and 1997 (n = 3563). <br/><br>
<br/><br>
Method: <br/><br>
Psychiatrists evaluated participants for mental disorders at several field investigations. In 1997, participants were also asked to complete the HSCL-25. Subjects with diagnoses of schizophrenia, dementia and certain other conditions were excluded leaving 1189 subjects aged 40-96 years. Diagnostic assessments by psychiatrists were compared with the results of the HSCL-25. Sensitivity and specificity were calculated at two cut-off levels of the HSCL-25 (1.55 and 1.75), and receiver operating characteristic (ROC) curves were plotted. The performance of the HSCL-25 was analysed with regard to anxiety and depression subscales. <br/><br>
<br/><br>
Results: <br/><br>
The concordance of HSCL-25 with clinical best-estimate diagnoses was low. The anxiety subscale discriminated better than the depressive subscale. <br/><br>
<br/><br>
Conclusions: <br/><br>
The correspondence between the clinical diagnoses made by psychiatrists and the HSCL-25 was not acceptable at a cut-off level 1.55. The HSCL-25 is limited in its ability to identify clinical syndromes. The HSCL-25 should be applied only as a preliminary screen for emotional distress and anxiety syndromes.}},
  author       = {{Mattisson, Cecilia and Bogren, Mats and Horstmann, Vibeke}},
  issn         = {{1502-4725}},
  language     = {{eng}},
  number       = {{3}},
  pages        = {{204--213}},
  publisher    = {{Informa Healthcare}},
  series       = {{Nordic Journal of Psychiatry}},
  title        = {{Correspondence between clinical diagnoses of depressive and anxiety disorders and diagnostic screening via the Hopkins Symptom Check List-25 in the Lundby Study.}},
  url          = {{http://dx.doi.org/10.3109/08039488.2012.711856}},
  doi          = {{10.3109/08039488.2012.711856}},
  volume       = {{67}},
  year         = {{2013}},
}