Short article : Presence, extent and location of pancreatic necrosis are independent of aetiology in acute pancreatitis
Verdonk, Robert C. ; Sternby, Hanna LU ; Dimova, Alexandra ; Ignatavicius, Povilas ; Koiva, Peter ; Penttila, Anne K. ; Ilzarbe, Lucas ; Regner, Sara LU
; Rosendahl, Jonas
and Bollen, Thomas L.
(2018)
In European Journal of Gastroenterology and Hepatology
30(3).
p.342-345
- Abstract
Objective The most common aetiologies of acute pancreatitis (AP) are gallstones, alcohol and idiopathic. The impact of the aetiology of AP on the extent and morphology of pancreatic and extrapancreatic necrosis (EXPN) has not been clearly established. The aim of the present study was to assess the influence of aetiology on the presence and location of pancreatic necrosis in patients with AP. Patients and methods We carried out a post-hoc analysis of a previously established multicentre cohort of patients with AP in whom a computed tomography was available for review. Clinical data were obtained from the medical records. All computed tomographies were revised by the same expert radiologist. The impact of aetiology on pancreatic and EXPN... (More)
Objective The most common aetiologies of acute pancreatitis (AP) are gallstones, alcohol and idiopathic. The impact of the aetiology of AP on the extent and morphology of pancreatic and extrapancreatic necrosis (EXPN) has not been clearly established. The aim of the present study was to assess the influence of aetiology on the presence and location of pancreatic necrosis in patients with AP. Patients and methods We carried out a post-hoc analysis of a previously established multicentre cohort of patients with AP in whom a computed tomography was available for review. Clinical data were obtained from the medical records. All computed tomographies were revised by the same expert radiologist. The impact of aetiology on pancreatic and EXPN was calculated. Results In total, 159 patients with necrotizing pancreatitis were identified from a cohort of 285 patients. The most frequent aetiologies were biliary (105 patients, 37%), followed by alcohol (102 patients, 36%) and other aetiologies including idiopathic (78 patients, 27%). No relationship was found between the aetiology and the presence of pancreatic necrosis, EXPN, location of pancreatic necrosis or presence of collections. Conclusion We found no association between the aetiology of AP and the presence, extent and anatomical location of pancreatic necrosis.
(Less)
- author
- Verdonk, Robert C.
; Sternby, Hanna
LU
; Dimova, Alexandra
; Ignatavicius, Povilas
; Koiva, Peter
; Penttila, Anne K.
; Ilzarbe, Lucas
; Regner, Sara
LU
; Rosendahl, Jonas
and Bollen, Thomas L.
- organization
- publishing date
- 2018
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- acute pancreatitis, alcohol, gallstones, necrosis
- in
- European Journal of Gastroenterology and Hepatology
- volume
- 30
- issue
- 3
- pages
- 4 pages
- publisher
- Lippincott Williams & Wilkins
- external identifiers
-
- scopus:85042367183
- pmid:29280919
- ISSN
- 0954-691X
- DOI
- 10.1097/MEG.0000000000001053
- language
- English
- LU publication?
- yes
- id
- af8ba891-0acf-48b5-87f1-a933bbf30cb3
- date added to LUP
- 2018-03-08 13:58:12
- date last changed
- 2024-05-13 06:37:17
@article{af8ba891-0acf-48b5-87f1-a933bbf30cb3,
abstract = {{<p>Objective The most common aetiologies of acute pancreatitis (AP) are gallstones, alcohol and idiopathic. The impact of the aetiology of AP on the extent and morphology of pancreatic and extrapancreatic necrosis (EXPN) has not been clearly established. The aim of the present study was to assess the influence of aetiology on the presence and location of pancreatic necrosis in patients with AP. Patients and methods We carried out a post-hoc analysis of a previously established multicentre cohort of patients with AP in whom a computed tomography was available for review. Clinical data were obtained from the medical records. All computed tomographies were revised by the same expert radiologist. The impact of aetiology on pancreatic and EXPN was calculated. Results In total, 159 patients with necrotizing pancreatitis were identified from a cohort of 285 patients. The most frequent aetiologies were biliary (105 patients, 37%), followed by alcohol (102 patients, 36%) and other aetiologies including idiopathic (78 patients, 27%). No relationship was found between the aetiology and the presence of pancreatic necrosis, EXPN, location of pancreatic necrosis or presence of collections. Conclusion We found no association between the aetiology of AP and the presence, extent and anatomical location of pancreatic necrosis.</p>}},
author = {{Verdonk, Robert C. and Sternby, Hanna and Dimova, Alexandra and Ignatavicius, Povilas and Koiva, Peter and Penttila, Anne K. and Ilzarbe, Lucas and Regner, Sara and Rosendahl, Jonas and Bollen, Thomas L.}},
issn = {{0954-691X}},
keywords = {{acute pancreatitis; alcohol; gallstones; necrosis}},
language = {{eng}},
number = {{3}},
pages = {{342--345}},
publisher = {{Lippincott Williams & Wilkins}},
series = {{European Journal of Gastroenterology and Hepatology}},
title = {{Short article : Presence, extent and location of pancreatic necrosis are independent of aetiology in acute pancreatitis}},
url = {{http://dx.doi.org/10.1097/MEG.0000000000001053}},
doi = {{10.1097/MEG.0000000000001053}},
volume = {{30}},
year = {{2018}},
}