Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Sacrificial polymers for nanofluidic channels in biological applications

Li, Wanli ; Tegenfeldt, Jonas O. ; Chen, Lei ; Austin, Robert H. ; Chou, Stephen Y. ; Kohl, Paul A. ; Krotine, Jeff and Sturm, James C. (2003) In Nanotechnology 14(6). p.578-583
Abstract

Chip based bio/chemical analysis relies on networks of fluidic channels that are connected to reaction chambers and sensors. For sensitive detection it is important to scale down the size of the channels so that they approach the relevant length scales of the molecules of interest. Here we have made sealed channels on the 100 nm scale using nanoimprinting to pattern the sacrificial polymer polynorbornene over areas of several square centimetres. We have combined channels of different cross sections and we have shown that the nanochannels can be made hydrophilic with DNA transported electrophoretically in these self-sealed channels.

Please use this url to cite or link to this publication:
author
; ; ; ; ; ; and
publishing date
type
Contribution to journal
publication status
published
in
Nanotechnology
volume
14
issue
6
pages
6 pages
publisher
IOP Publishing
external identifiers
  • scopus:0037529339
ISSN
0957-4484
DOI
10.1088/0957-4484/14/6/302
language
English
LU publication?
no
id
b030fbe9-a320-4b6b-b33f-10ab1ff2dde1
date added to LUP
2018-10-20 10:37:13
date last changed
2022-01-31 06:19:35
@article{b030fbe9-a320-4b6b-b33f-10ab1ff2dde1,
  abstract     = {{<p>Chip based bio/chemical analysis relies on networks of fluidic channels that are connected to reaction chambers and sensors. For sensitive detection it is important to scale down the size of the channels so that they approach the relevant length scales of the molecules of interest. Here we have made sealed channels on the 100 nm scale using nanoimprinting to pattern the sacrificial polymer polynorbornene over areas of several square centimetres. We have combined channels of different cross sections and we have shown that the nanochannels can be made hydrophilic with DNA transported electrophoretically in these self-sealed channels.</p>}},
  author       = {{Li, Wanli and Tegenfeldt, Jonas O. and Chen, Lei and Austin, Robert H. and Chou, Stephen Y. and Kohl, Paul A. and Krotine, Jeff and Sturm, James C.}},
  issn         = {{0957-4484}},
  language     = {{eng}},
  month        = {{06}},
  number       = {{6}},
  pages        = {{578--583}},
  publisher    = {{IOP Publishing}},
  series       = {{Nanotechnology}},
  title        = {{Sacrificial polymers for nanofluidic channels in biological applications}},
  url          = {{http://dx.doi.org/10.1088/0957-4484/14/6/302}},
  doi          = {{10.1088/0957-4484/14/6/302}},
  volume       = {{14}},
  year         = {{2003}},
}